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51.
ABSTRACT

The past decade has seen an increase in anti-counterfeiting practices, especially in the pharmaceutical field. These practices aim at reducing the number of bad medicines available on the market, especially in countries where pharmaceutical regulation is still weak. But they have been accused of serving the interests of Big Pharma by reinforcing intellectual property instead of promoting better quality medicines. Based on a study of the controversies provoked by anti-counterfeiting laws and devices, this paper analyses anti-counterfeiting politics and shows: (a) the aim of this mode of government is to discriminate between medicines in order to regulate the value attached to distribution processes and (b) the tensions and contradictions which characterize anti-counterfeiting discourses and practices. As such, a central characteristic of pharmaceutical markets is the shift of value conflicts towards circulation and distribution rather than production. The securitization of pharmaceutical flows, rather than being in addition to the production of pharmaceuticals, emerges as a new disputed way of producing economic value, legality and social legitimacy for globalized technical commodities such as medicines.  相似文献   
52.
This study investigated end-game and transient changes in running activities and whether these were concomitantly associated with reductions in skill-related performance in senior international rugby union match-play. Altogether, 18 official matches were analysed (322 individual observations) using computerised video-based tracking and event coding (Amisco Pro®, SUP, Nice, France). In forwards and backs, trivial to small reductions (% difference: ?2.1, ±1.3 to ?10.0, ±4.0%) in total distance and that covered at high speeds (>18.0?km?h?1) occurred in the second- versus the first-half while there were trivial differences in skill-related performance measures (?2.3, ±4.5 to 7.5, ±14.0%). In both positions, small to moderate declines (?42, ±10 to ?21, ±7%) occurred in high-speed running in the final 10-min and 5-min periods versus mean values for all other 10-min and 5-min periods throughout the game while only small changes (?18, ±51 to 13, ±41%) in skill-related performance were observed. Trivial changes in running and skill-related performance (?11, ±74 to 7, ±39%) were observed in the 5-min period immediately following the most intense 5-minute periods of play compared to mean performance over the other 5-min periods. These findings suggest that international rugby union players were generally able to maintain skill-related performance over the course of match-play even when declines in running performance occurred.  相似文献   
53.
Abstract

The article discusses general structure and dynamics of the sports science research content as obtained from the analysis of 21998 European College of Sport Science abstracts belonging to 12 science topics. The structural analysis showed intertwined multidisciplinary and unifying tendencies structured along horizontal (scope) and vertical (level) axes. Methodological (instrumental and mode of inquiry) integrative tendencies are dominant. Theoretical integrative tendencies are much less detectable along both horizontal and vertical axes. The dynamic analysis of written abstracts text content over the 19 years reveals the contextualizing and guiding role of thematic skeletons of each sports science topic in forming more detailed contingent research ideas and the role of the latter in stabilizing and procreating the former. This circular causality between both hierarchical levels and functioning on separate characteristic time scales is crucial for understanding how stable research traditions self-maintain and self-procreate through innovative contingencies. The structure of sports science continuously rebuilds itself through use and re-use of contingent research ideas. The thematic skeleton ensures its identity and the contingent conceptual sets its flexibility and adaptability to different research or applicative problems.  相似文献   
54.
In this study, we examined the effectiveness of auditory concurrent feedback on body segmental alignment during the circle movement performed on a pommel horse. Eighteen gymnasts were assigned to one of two groups: a concurrent auditory feedback group (experimental) or a control group that received no concurrent feedback. After 2 weeks of training (300 circles), the body segmental alignment (BSA) of the experimental group had improved by 2.3% between the pre test (85.7 +/- 4.8% BSA(max)) and the post test (87.7 +/- 4.0% BSA(max)). Furthermore, the results of a retention test administered 2 weeks after the post test revealed no decline in performance for the experimental group. No gains in body segmental alignment were found for the control group. It was concluded that augmented auditory feedback made available in real time can be used to correct complex movements, such as the circle movement on a pommel horse, and does not appear to lead to information-dependence despite the frequent administration of feedback. The auditory signal available in real time could help gymnasts to become more objective about their own intrinsic information necessary for the refinement of the circle movement.  相似文献   
55.
In this study, we examined the effect of rapidly increased training volume and intensity on hormonal responses (salivary cortisol [C] and urinary dehydroepiandrosterone sulphate [DHEA-S]) and recovery-stress state perceived by 12 female cyclists. Over the 4-day experimental period, there was an average increase in training load of approximately 122% compared with that during the previous 12 days. Scores on subscales of the Recovery Stress Questionnaire for Athletes increased for the somatic component of stress (Fatigue, Emotional Stress and Social Stress; P<0.05) and decreased the factor indicating recovery (General Well Being; P<0.05) after the heavy training period. The training programme increased resting concentrations of salivary cortisol (P<0.05) and decreased the DHEA-S/C ratio (P<0.05). The increase in training load of cyclists was correlated with this hormonal ratio (r=-0.48, P<0.05). Changes in resting cortisol concentration as a result of heavy training stress were positively related to the change in Physical Complaints (r=0.69, P<0.01). Negative relationships were also found between changes in the DHEA-S/C ratio and changes in the somatic component of stress. The present results suggest that there is a dose-response relationship between increased training load, resting DHEA-S/C ratio and subjective assessment of stress and recovery, implying that this ratio could be used as an indicator of training status in female athletes.  相似文献   
56.
Tertiary Education and Management - The global trend of increasing participation rates, coupled with regional goals to increase participation in higher education, such as the...  相似文献   
57.
In this study, we assessed arm coordination in the backstroke over increasing speeds by adapting the index of coordination originally used in the front crawl. Fourteen elite male backstroke swimmers swam four trials of 25 m at the speeds corresponding to the 400-m, 200-m, 100-m, and 50-m events. The six phases of the arm stroke were identified by video analysis and then used to calculate the index of coordination, which corresponded to the time between the propulsive phases of the two arms. With increases in speed, the elite swimmers increased the stroke rate, the relative duration of their arm pull, and their index of coordination, and decreased the distance per stroke (P < 0.05). Arm coordination was always in catch-up (index of coordination of -12.9%) because the alternating body-roll and the small shoulder flexibility did not allow the opposition or superposition coordination seen in the front crawl. This new method also quantified the relative duration of the hand's lag time at the thigh, which did not change ( approximately 2%) with increasing speed for the elite swimmers. The index of coordination enables coaches to assess mistakes in backstroke coordination, particularly in the hand's lag time at the thigh.  相似文献   
58.
The purpose of this study was to determine whether the Index of Coordination (IdC) and the propulsive phase durations can differentiate performance level during a maximal 400-m front crawl swim trial. Sixteen male swimmers constituted two groups based on performance level (G1: experts; G2: recreational). All participants swam the 400-m front crawl at maximal speed. Video analysis determined the stroke (swimming speed, stroke length, stroke rate) and coordination (IdC) parameters for every 50 m. Both stroke and coordination parameters discriminated performance level. The expert group had significantly higher values for speed and stroke length and lower values for the relative propulsive phase duration and IdC (p < .05). However there was no significant change in coordination parameters for either group throughout the trial. This suggests that, when associated with greater stroke length, catch-up coordination can be an efficient coordination mode that reflects optimal drag/propulsion adaptation. This finding provides new insight into swimmers' adaptations in a middle-distance event.  相似文献   
59.
In 1963, the Nobel Prize-winning ethologist Niko Tinbergen proposed a framework for the scientific study of animal behaviour by outlining four questions that should be answered to have a complete understanding: causation, ontogeny, function and evolution. At present, Tinbergen’s framework is still considered the best way to guide animal behavioural research. Given the importance in science instruction of demonstrating how scientists work and ask questions, we investigated to what extent Tinbergen’s questions are addressed in biology textbooks in secondary education in Flanders, Belgium, and represented in upper-secondary and first-year university students’ explanations of behaviour in general and of specific animal behaviours. Our results revealed that teaching of animal behaviour mainly addresses ontogeny and causation, and that Tinbergen’s framework is not explicitly referred to. Students typically addressed only one or two questions, with the majority addressing causation or both causation and ontogeny when explaining behaviour in general, but function or causation and function when explaining specific animal behaviours. This high prevalence of function may be due to teleological thinking. Evolution was completely neglected, even in university students who had recently completed an evolution course. Our results revealed that transfer of the concepts of ontogeny and evolution was (almost) absent. We argue why Tinbergen’s framework should be an integral part of any biology curriculum.  相似文献   
60.
Abstract

In this study, we examined the effect of rapidly increased training volume and intensity on hormonal responses (salivary cortisol [C] and urinary dehydroepiandrosterone sulphate [DHEA-S]) and recovery-stress state perceived by 12 female cyclists. Over the 4-day experimental period, there was an average increase in training load of approximately 122% compared with that during the previous 12 days. Scores on subscales of the Recovery Stress Questionnaire for Athletes increased for the somatic component of stress (Fatigue, Emotional Stress and Social Stress; P < 0.05) and decreased the factor indicating recovery (General Well Being; P < 0.05) after the heavy training period. The training programme increased resting concentrations of salivary cortisol (P < 0.05) and decreased the DHEA-S/C ratio (P < 0.05). The increase in training load of cyclists was correlated with this hormonal ratio (r = ?0.48, P < 0.05). Changes in resting cortisol concentration as a result of heavy training stress were positively related to the change in Physical Complaints (r = 0.69, P < 0.01). Negative relationships were also found between changes in the DHEA-S/C ratio and changes in the somatic component of stress. The present results suggest that there is a dose–response relationship between increased training load, resting DHEA-S/C ratio and subjective assessment of stress and recovery, implying that this ratio could be used as an indicator of training status in female athletes.  相似文献   
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