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Effects of competition, exercise, and mental stress on secretory immunity   总被引:2,自引:0,他引:2  
It has been suggested that the psychological stress associated with competitive sports events may help to explain the increased susceptibility to respiratory infections due to reductions in secretory immunity. In the current study, we investigated the influence of competitive exercise and psychological stress on secretory immunoglobulin A (s-IgA). Salivary s-IgA and heart rate were measured in 62 healthy young recreationally active men at rest and, in a between-subjects design, following one of four 8-min tasks: mental arithmetic, cycling at workloads of 60 to 180 W (mean = 146 W), mental arithmetic while cycling, or competitive cycling. Mental arithmetic was associated with significant increases in s-IgA concentration (mean = 49 microg.min(-1)) and s-IgA secretion rate (mean = 25 microg.ml(-1)) compared with rest, while mental arithmetic combined with exercise was associated with a significant increase in s-IgA concentration only (mean = 124 microg.min(-1)). In contrast, competitive exercise and exercise alone did not influence s-IgA concentration or secretion rate. Heart rate increased modestly to mental arithmetic (mean = 7 beats.min(-1)) and substantially, and similarly, to the three exercise tasks (mean = 56(62 beats.min(-1)). The hypothesis that the psychological stress of competitive exercise contributes to increased susceptibility to infection via reductions in s-IgA requires further investigation.  相似文献   
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The British Council is part of Britain's overseas representation and its aim is to promote a wider knowledge of Britain and the English language, and to develop closer cultural ties and better understanding between Britain and other nations. Thus it is concerned with cultural relations in the widest sense, embracing education, science and the arts, and it promotes all kinds of professional and intellectual interchange. In France, as elsewhere in Europe, the Council operates a number of programmes to facilitate these exchanges, and in this article — although it is naturally based on Anglo-French scientific exchanges — I hope to give an idea of the sort of schemes which are also available in other European countries.  相似文献   
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Willmott GR  Platt M  Lee GU 《Biomicrofluidics》2012,6(1):14103-1410315
Tunable pores (TPs) have been used for resistive pulse sensing of 1 μm superparamagnetic beads, both dispersed and within a magnetic field. Upon application of this field, magnetic supraparticle structures (SPSs) were observed. Onset of aggregation was most effectively indicated by an increase in the mean event magnitude, with data collected using an automated thresholding method. Simulations enabled discrimination between resistive pulses caused by dimers and individual particles. Distinct but time-correlated peaks were often observed, suggesting that SPSs became separated in pressure-driven flow focused at the pore constriction. The distinct properties of magnetophoretic and pressure-driven transport mechanisms can explain variations in the event rate when particles move through an asymmetric pore in either direction, with or without a magnetic field applied. Use of TPs for resistive pulse sensing holds potential for efficient, versatile analysis and measurement of nano- and microparticles, while magnetic beads and particle aggregation play important roles in many prospective biosensing applications.  相似文献   
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In this study a method for determining elbow extension and elbow abduction for a cricket bowling delivery was developed and assessed for Jenny Gunn who has hypermobility in both elbows and whose bowling action has been repeatedly queried by umpires. Bowling is a dynamic activity which is assessed visually in real time in a cricket match by an umpire. When the legality of a bowler's action is questioned by an umpire a quantitative analysis is undertaken using a marker based motion analysis system. This method of quantifying elbow extension should agree with a visual assessment of when the arm is "straight" and should minimise the effects of marker movement. A set of six markers on the bowling arm were used to calculate elbow angles. Differences of up to 1° for elbow extension and up to 2° for elbow abduction were found when angles calculated from the marker set for static straight arm trials were compared with measurements taken by a chartered sports physiotherapist. In addition comparison of elbow extension angles at ball release calculated from the markers during bowling trials with those measured from high speed video also showed good agreement with mean differences of 0°±2°.  相似文献   
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