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Who borrows laptop computers in an academic health sciences library? Why do they choose to check out laptops? In a survey, laptop computer users responded that the laptops were used most frequently to do class-related work. Laptops were most often checked out because they could be taken to a quiet area of the library or to where the user had more room to work. The majority of such borrowers were satisfied or very satisfied with the laptops and the service from the library. The majority of those completing the survey were medical school students and graduate students. The circulation of laptop computers at this academic health sciences library is a very successful and popular program.  相似文献   
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Pangolins are among the most critically endangered animals due to heavy poaching and worldwide trafficking. However, their demographic histories and the genomic consequences of their recent population declines remain unknown. We generated high-quality de novo reference genomes for critically endangered Malayan (Manis javanica, MJ) and Chinese (M. pentadactyla, MP) pangolins and re-sequencing population genomic data from 74 MJs and 23 MPs. We recovered the population identities of illegally traded pangolins and previously unrecognized genetic populations that should be protected as evolutionarily distinct conservation units. Demographic reconstruction suggested environmental changes have resulted in a population size fluctuation of pangolins. Additionally, recent population size declines due to human activities have resulted in an increase in inbreeding and genetic load. Deleterious mutations were enriched in genes related to cancer/diseases and cholesterol homeostasis, which may have increased their susceptibility to diseases and decreased their survival potential to adapt to environmental changes and high-cholesterol diets. This comprehensive study provides not only high-quality pangolin reference genomes, but also valuable information concerning the driving factors of long-term population size fluctuations and the genomic impact of recent population size declines due to human activities, which is essential for pangolin conservation management and global action planning.  相似文献   
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Afforestation in China provides carbon sequestration and prevents soil erosion, but its remote impacts on climate in other regions via the coupling of forest energy fluxes with atmospheric circulation are largely unknown. Here, we prescribe inventory-based forest cover change and satellite-observed leaf area index from 1982 to 2011 in a coupled land-atmosphere model to simulate their biophysical climate effects. Both local and global surface air temperatures show a seasonal contrast in response to past vegetation cover expansion over China: a phenomenon we primarily attribute to a variation of seasonality of vegetation greening. A large cooling in spring results in concurrent decreases in geopotential height over China and zonal wind over Mongolia, causing a dipole structure in the upper troposphere over the Arctic. This accounts for ∼58% of simulated spring warming over the Russian Arctic and ∼61% of simulated spring cooling over the Canadian Artic. Our results imply that spring vegetation dynamics in China may affect climate in northern high latitudes.  相似文献   
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This study explored the relationship between metacognition and intelligence in a group of normal adolescents. The relationship has strong theoretical support in current conceptions of intelligence. For the purposes of this study metacognition was assessed across three different cognitive problem sets. Correlational analyses indicated a nonsignificant relationship between intelligence and metacognition. These results suggest that tests of metacognition and intelligence may tap unrelated aspects of cognition and that additional research will be required to understand the relationship between these two constructs.  相似文献   
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IntroductionTwo new formulas, the Martin-Hopkins and the Sampson formula, were recently developed to overcome shortcomings of the Friedewald formula for calculating LDL-cholesterol. We aimed to compare the concordance of the two formulas with apolipoprotein B (apoB), a surrogate marker of the number of LDL particles.Materials and methodsIn a study of serum lipid data of 1179 patients who consulted the AZ St-Jan Hospital Bruges for cardiovascular risk assessment, the correlation and concordance of the Friedewald, Martin-Hopkins and Sampson formulas with apoB concentration, measured by immunonephelometry, were determined and compared.ResultsThe Martin-Hopkins formula showed significantly higher correlation coefficient than the Friedewald formula with apoB in the entire dataset and in patients with low LDL-cholesterol < 1.8 mmol/L. Both Martin-Hopkins and Sampson formulas yielded > 70% concordance of LDL-cholesterol with regard to treatment group classification based on population-equivalent thresholds of apoB in hypertriglyceridemic patients (2-4.5 mmol/L), with the highest concordance (75.6%) obtained using Martin-Hopkins formula vs. 60.5% with Friedewald formula.ConclusionThe Martin-Hopkins (and, to a lesser extent, Sampson) formula is more closely associated with the number of LDL particles than Friedewald formula. This, in combination with literature evidence of lesser accuracy of the Friedewald formula, is an argument to switch from Friedewald to a modified, improved formula.  相似文献   
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The aim of present study was to examine the relationships between serum and salivary values of free testosterone, dehydroepiandrosterone, and cortisol before and after a session of resistance exercise. Twenty-eight healthy men (mean age 40 years, s = 4) participated in the present study. Serum and salivary samples were collected at rest and after a multiple-sets resistance exercise protocol, of approximately 25 minutes duration. Concentrations of free testosterone, dehydroepiandrosterone, and cortisol were measured using radioimmunoassay kits. No significant correlation was observed between serum free testosterone and salivary testosterone (r = 0.22 to 0.26, P > 0.05). Serum cortisol was significantly correlated with salivary cortisol before (r = 0.52, P = 0.005) and after (r = 0.62, P = 0.001) the exercise protocol. Serum and salivary concentrations of dehydroepiandrosterone were significantly correlated before (r = 0.68, P < 0.001) and after (r = 0.7, P < 0.001) exercise. The results of the present study suggest that even under exercise conditions, the salivary values of cortisol and dehydroepiandrosterone can reflect the behaviour of these hormones in blood. However, further studies are necessary to verify if salivary testosterone reflects the behaviour of serum free testosterone during resistance exercise.  相似文献   
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This study compared heart rate recovery (HRR) after incremental maximal exercise performed at the same external power output (Pext) on dry land ergocycle (DE) vs. immersible ergocycle (IE). Fifteen young healthy participants (30?±?7 years, 13 men and 2 women) performed incremental maximal exercise tests on DE and on IE. The initial Pext on DE was 25?W and was increased by 25?W/min at a pedalling cadence between 60 and 80?rpm, while during IE immersion at chest level in thermoneutral water (30°C), the initial Pext deployment was at a cadence of 40?rpm which was increased by 10?rpm until 70?rpm and thereafter by 5?rpm until exhaustion. Gas exchange and heart rate (HR) were measured continuously during exercise and recovery for 5?min. Maximal HR (DE: 176?±?15 vs. IE 169?±?12?bpm) reached by the subjects in the two conditions did not differ (P?>?.05). Parasympathetic reactivation parameters (ΔHR from 10 to 300?s) were compared during the DE and IE HR recovery recordings. During the IE recovery, parasympathetic reactivation in the early phase was more predominant (HRR at Δ10–Δ60?s, P?<?.05), but similar in the late phase (HRR at Δ120–Δ300?s, P?>?.05) when compared to the DE condition. In conclusion, incremental maximal IE exercise at chest level immersion in thermoneutral water accelerates the early phase parasympathetic reactivation compared to DE in healthy young participants.  相似文献   
19.
Abstract

This article discusses the application of digital video to multimedia, and looks at the pros and cons of two different approaches. It also considers the standards of equipment for various uses.  相似文献   
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