Tandem Biocatalysis by CotA-TJ102@UIO-66-NH2 and Novozym 435 for Highly Selective Transformation of HMF into FDCA     

Chang  Xin  Zhang  Chengyu  Gao  Lan  Liu  Xiao  You  Shengping  Qi  Wei  Wang  Kang  Guo  Xin  Su  Rongxin  Lu  Han  He  Zhimin 《天津大学学报(英文版)》2019,25(5):488-496

2,5-Furandicarboxylic acid(FDCA) is a potential biorenewable chemical for applications including plastics, polyamides, drugs, etc. The selective biosynthesis of FDCA from 5-hydroxymethylfurfural(HMF) by a specific enzyme poses a great challenge. In this study, we reported an efficient strategy to produce FDCA from HMF by the tandem biocatalysis of laccase(Cot A-TJ102@UIO-66-NH_2) and Novozym 435. For the first step, a nanoparticle metal–organic framework was synthesized as a carrier to immobilize Cot A-TJ102@UIO-66-NH_2, which was assigned for the production of 5-formyl-2-furancarboxylic acid(FFCA) and featured an enzyme loading of 255.54 mg/g, specific activity of 135.90 U/mg, and solid loading ratio of 99.65%. Under optimal conditions, an ideal FFCA yield of 98.5% was achieved, and the Cot A-TJ102@UIO-66-NH_2 presented a high recycling capacity after 10 cycles. For the second step, Novozym 435 was applied for the further conversion of FFCA into FDCA, presenting a high FDCA yield of 95.5% under the optimized conditions. Novozym 435 also exhibited a high recyclability after eight cycles. As a result, the tandem biocatalysis strategy provided a 94.2% FDCA yield from HMF, indicating its excellence as a method for FDCA production.  相似文献   

Ecological Mural as Community Reconnection     

Young Imm Kang Song  Jo Ann Gammel 《The International Journal of Art & Design Education》2011,30(2):266-278

Murals are particularly visually captivating forms of public art due to their size and accessibility. Mural images also capture public attention and provoke viewers to explore layers of meaning and find hidden stories. They are often in places that people come to visit, study, play, congregate and discuss matters that may relate to the content of the mural. To this end, murals can be effective tools for helping communities think about their environmental issues. This article discusses the Mystic River mural project in Somerville, Massachusetts, USA. It addresses how the local art councils, mural artists, local students, community members and non‐profit organisations collaborated to carry out this ongoing mural project. The purpose of this research is to examine how Mystic River eco‐murals were created, what challenges and benefits the eco‐murals provided, how local social concerns were represented through the eco‐murals, how eco‐murals can continue to promote environmental awareness and inspire youth about their community and the local environment, and how the mural can continue to reflect or affect the meaning of the place. This process can serve as an example for other communities that seek to address their environmental concerns through public art.  相似文献   

就业、创业教育模式新探——以赛扶教育为例   总被引：2，自引：1，他引：1  

佴康 《扬州大学学报(高教研究版)》2011,15(2):51-54

赛扶又称＂全球大学生企业家联盟＂,是一个全球性的大学生公益创业实践组织,对大学生的创业、就业素质培养和实践教育具有重要作用。探求赛扶组织成功的奥秘,用心理学、教育学的方法配合调查问卷结果分析其利用社会资源,构建就业、创业教育实践平台模式;体验式就业、创业教育的模式;创业精英意识培养的模式,并对现在的就业、创业教育中的瓶颈问题提出可行性方案,可以帮助学生更好地进行创业、就业。  相似文献   

《电力电子学》多媒体交互式虚拟实验的实现技术   总被引：8，自引：0，他引：8  

邓弘  康勇  陈坚 《现代教育技术》2003,13(3):44-47

该文介绍了针对大学本科基础专业课程《电力电子学》教学课件中虚拟实验的实现技术。Flash软件的ActionScript是一种面向对象的编程方法,通过Flash深入编程,该研究实现了由JAVA编程达到的虚拟试验效果,同时探索了严格意义上的交互式虚拟课件的技术实现方法。  相似文献   

非税收入规范化管理研究   总被引：10，自引：0，他引：10  

贾康  刘军民 《华中师范大学学报(人文社会科学版)》2005,44(3):23-32

非税收入是政府收入体系的一个有机组成部分。我国非税收入管理的突出问题是数额大,征收主体多元化,管理规范性差,带来严重负面效应。本文在分析上述问题形成原因的基础上,提出改革和规范我国非税收入管理的思路,即对非税收入的不同种类区别对待,分流归位,依法立项,建立和完善规范化征管体系,并以治本为目的实施财政、行政、法制、投融资等方面的配套改革,文中还就此提出了一系列具体措施建议。  相似文献   

Simple Preparation of Spherical Activated Carbon with Mesoporous Structure from Phenolic Resol and Associated Catalytic Performance in Isobutane Dehydrogenation     

Xitao Wang  Chunyu Xin  Chunjie Shi  Anhua Dong  Kang Wang 《天津大学学报(英文版)》2018,(4)

This study provides a detailed report on the synthesis of spherical activated carbon with mesoporous structure using a soluble low molecular weight phenolic resol precursor through an ammonium alginate assisted sol–gel method. The effects of calcinating temperature and the addition of CaCO_3 as a pore-enlarging agent on texture structure and catalytic performance in isobutane dehydrogenation to isobutene were investigated. Characterization of N_2 sorption,mechanical strength tests,and optical photographs confirmed that the obtained carbon materials had high mechanical strength,a good degree of sphericity,and a large surface area. Introducing CaCO_3 as a pore-enlarging agent during the preparation process promoted the formation of a mesoporous structure of carbon spheres and evidently increased the surface area and oxygen content,which can improve isobutane conversion and isobutene selectivity of these carbon spheres. The conversion of isobutane reached up to 28% for this spherical activated carbon,and the selectivity of isobutene reached up to 96%. Isobutane conversion increased with an increase in calcination temperature due to an increase in the oxygen content,whereas the selectivity of isobutene decreased due to the slight decrease in the specific surface area.  相似文献   

试论区域科技创新体系的构建与推进     

康壮苏 《呼伦贝尔学院学报》2006,14(5):75-77

文章论述了构建区域科技创新体系应遵循的基本原则,并根据相关原则及各子系统的功能和相互关系构筑了区域科技创新体系组织结构的框架模型,即认为:区域科技创新体系包括两个层次、六个子系统。最后提出了推进区域科技创新体系建设的一些对策措施。  相似文献   

浅谈专业英语授课中的同步复习     

曹康 《乌鲁木齐成人教育学院学报》2004,12(2):63-64

随着与国际社会交流机会的增多．英语水平成为衡量学生能力的一个重要方面，英语教学是高等职业技术学院教育中十分重要的一部分。当前，高职生英语基础较差．在专业英语授课过程中要强调同步复习这一环节。  相似文献   

提高思想政治理论课教学实效性的思考     

康小莉 《石家庄学院学报》2005,7(5):99-102,106

思想政治理论课教学是大学生思想政治教育的主渠道和主阵地。为了提高新形势下思想政治理论课教学的实效性，必须通过以下环节和措施来实现：重点提高思想政治理论课教师的政治素养，进一步优化教学内容，改进教学方法，完善实践和考试环节，使思想政治理论课教学在思想道德建设方面起到独特的作用。  相似文献   

高等职业教育专业设置特色分析   总被引：1，自引：0，他引：1  

康礼志  徐莹 《武汉工程职业技术学院学报》2006,18(3):85-88

专业设置是高等职业教育的基础。在教育比较的基础上，分析了高等职业教育专业设置的原则特色、结构特色、层次特色、名称的形式特色和机制特色，并就特色专业建设进行了探讨。力求为高等职业教育建设特色专业提供思路。  相似文献