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With increasing concerns in the UK about the positive mental well-being and flourishing of children, this research, using drama and creative writing with primary school teachers, children and a theatre company, looks at the links between creative processes and children's well-being. This pedagogy applies a capability approach and we use this lens to examine children's critical reflections on the project. Interview data highlight the link between agency, social imagination and subjective well-being. The study offers some concrete examples of the ways in which creative processes can move beyond an outcome-based understanding of the curriculum by offering a legitimate space for children to explore their values and develop competencies which are crucial for well-being in the 21st century.  相似文献   
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The remediation of language skill deficits has a positive impact on school success. Thus, intervention methods that contribute to the acquisition maintenance and generalisation of language skills during the preschool years are of value. Researchers have studied learning from modelled behaviour for some time. The more like the individual the model was perceived to be, the more effective the results. It may be logical to assume that if an individual were to observe him/herself being successful at a task, self-efficacy would increase. This appears to be the case in this study, in which video self-modelling was used with a preschooler with language delays.  相似文献   
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A sodium copper formate, first described in 2002, can also form on copper alloys with sodium originating from soda glass hydrolysis. The frequent occurrence (50% of 250 cases of glass-induced metal corrosion) is due to the presence of formaldehyde emissions in storage and its direct reaction to formate in the alkaline surface films. The compound can be produced without the presence of acetate when chalconatronite or metal coupons immersed in soda solution are exposed to formaldehyde vapours. The crystal structure, derived from X-ray powder diffraction, yielded the sum formula Cu4Na4O(HCOO)8(OH)2·4H2O. Except for the absence of acetate in the structure, this is in good agreement with the 2002 publication. To assess which kind of combined glass/metal objects are affected, a number of large museum collections were surveyed. Sodium copper formate was detected as a corrosion product using mainly micro-Raman spectroscopy, for instance, on 18 painted Limoges enamels, eight glass vessels with metal mountings, glass beads on metal wire from 11 bridal crowns, nine Christmas tree balls with wire decoration, 40 pieces of jewellery with glass gems, three daguerreotypes, and one miniature with cover glasses.  相似文献   
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Introduction

Nowadays, on-a-chip capillary electrophoresis is a routine method for the detection of PCR fragments. The Agilent 2100 Bioanalyzer was one of the first commercial devices in this field. Our project was designed to study the characteristics of Agilent DNA 1000 kit in PCR fragment analysis as a part of circulating tumour cell (CTC) detection technique. Despite the common use of this kit a complex analysis of the results from a long-term project is still missing.

Materials and methods

A commercially available Agilent DNA 1000 kit was used as a final step in the CTC detection (AdnaTest) for the determination of the presence of PCR fragments generated by Multiplex PCR. Data from 30 prostate cancer patients obtained during two years of research were analyzed to determine the trueness and precision of the PCR fragment size determination. Additional experiments were performed to demonstrate the precision (repeatability, reproducibility) and robustness of PCR fragment concentration determination.

Results

The trueness and precision of the size determination was below 3% and 2% respectively. The repeatability of the concentration determination was below 15%. The difference in concentration determination increases when Multiplex-PCR/storage step is added between the two measurements of one sample.

Conclusions

The characteristics established in our study are in concordance with the manufacturer’s specifications established for a ladder as a sample. However, the concentration determination may vary depending on chip preparation, sample storage and concentration. The 15% variation of concentration determination repeatability was shown to be partly proportional and can be suppressed by proper normalization.Key words: lab-on-a-chip devices, capillary electrophoresis, multiplex PCR, circulating tumour cells, Agilent DNA 1000 kit  相似文献   
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小黑猩猩,亦称为倭黑猩猩(pygmychimpangee).外形及生话习性酷似黑猩猩,但上肢更长更细,身体细长,面部不那么向前突出.小黑猩猩在野生环境中的数量在减少,主要原因是人类破坏其森林栖息地以及非法捕猎.  相似文献   
160.
The paper delineates and explains an emerging, but significant, form of digital information seeking behaviour among information consumers, which the authors have called ‘bouncing’. The evidence for this behaviour has emerged from five years of deep log analysis studies – an advanced form of transaction log analysis – of a wide range of users of digital information resources. Much of the evidence and discussion provided comes from the scholarly communication field. Two main bouncing metrics were applied in the log studies: site penetration, which is the number of items or pages viewed in a session, and return visits. The evidence shows that (1) a high proportion of people view just a few items or pages during a visit to a site and, (2) a high proportion of visitors either do not come back to the site or they did so infrequently. Typically those who penetrated a site least tended to return the least frequently. These people are termed ‘bouncers’. They bounce into the site and then bounce out again, presumably, to another site, as a high proportion of them do not appear to come back again. Possible explanations – negative and positive, for the form of behaviour are discussed.  相似文献   
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