Differential Susceptibility in Early Literacy Instruction Through Computer Games: The Role of the Dopamine D4 Receptor Gene (DRD4)     

Cornelia A. T. Kegel  Adriana G. Bus  Marinus H. van IJzendoorn 《Mind, Brain, and Education》2011,5(2):71-78

Not every child seems equally susceptible to the same parental, educational, or environmental influences even if cognitive level is similar. This study is the first randomized controlled trial to apply the differential susceptibility paradigm to education in relation to children's genotype and early literacy skills. A randomized pretest–posttest control group design was used to examine the effects of the Intelligent Tutoring System Living Letters. Two intervention groups were created, 1 receiving feedback and 1 completing the program without feedback, and 1 control group. Carriers of the long variant of the dopamine D4 receptor gene (DRD4 7‐repeat) profited most from the computer program with positive feedback, whereas they performed at the lowest level of early literacy skills in the absence of such feedback. Our findings suggest that behind modest overall educational intervention effects a strong effect on a subgroup of susceptible children may be hidden.  相似文献   

Cultural Beliefs and Disability: Implications for Rehabilitation Counsellors     

Quintin Boston  Paige N. Dunlap  Glacia Ethridge  Erin Barnes  Angel R. Dowden  Myshalae J. Euring 《International journal for the advancement of counseling》2015,37(4):367-374

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A Tense Moment     

Adriana LaFayette 《The Educational forum》2013,77(1)

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Cognitive and environmental predictors of early literacy skills     

Davidse NJ  de Jong MT  Bus AG  Huijbregts SC  Swaab H 《Reading and writing》2011,24(4):395-412

Not all young children benefit from book exposure in preschool age. It is claimed that the ability to hold information in mind (short-term memory), to ignore distraction (inhibition), and to focus attention and stay focused (sustained attention) may have a moderating effect on children’s reactions to the home literacy environment. In a group of 228 junior kindergarten children with a native Dutch background, with a mean age of 54.29 months (SD = 2.12 months), we explored therefore the relationship between book exposure, cognitive control and early literacy skills. Parents filled in a HLE questionnaire (book sharing frequency and an author recognition checklist as indicator of parental leisure reading habits), and children completed several tests in individual sessions with the researcher (a book-cover recognition test, PPVT, letter knowledge test, the subtests categories and patterns of the SON, and cognitive control measures namely digit span of the KABC, a peg tapping task and sustained attention of the ANT). Main findings were: (1) Children’s storybook knowledge mediated the relationship between home literacy environment and literacy skills. (2) Both vocabulary and letter knowledge were predicted by book exposure. (3) Short-term memory predicted vocabulary over and above book exposure. (4) None of the cognitive control mechanisms moderated the beneficial effects of book exposure.  相似文献   

Experience of cooperative learning in engineering   总被引：1，自引：1，他引：0  

Rocio Maceiras  Angeles Cancela  Santiago Urréjola  Angel Sánchez 《European Journal of Engineering Education》2011,36(1):13-19

The objective of this work is to share the authors’ experience towards a different mode of teaching/learning method. Cooperative learning (Jigsaw) was employed on the University of Vigo's fourth-year engineering students. The results of the experience show that cooperative learning is quite a viable alternative to the classical way of lecturing at the university when the number of students is not too high. The authors’ observation indicates that students did not show a lot of interest towards the new learning style but their resistance changed once they began the activity. The Jigsaw method has proved to be a useful tool for improving the learning process so that students have the opportunity to participate actively in the learning activities.  相似文献   

Pheromone synthesis in a biomicroreactor coated with anti-adsorption polyelectrolyte multilayer     

Dimov N  Muñoz L  Carot-Sans G  Verhoeven ML  Bula WP  Kocer G  Guerrero A  Gardeniers HJ 《Biomicrofluidics》2011,5(3):34102-3410212

To prepare a biosynthetic module in an infochemical communication project, we designed a silicon/glass microreactor with anti-adsorption polyelectrolyte multilayer coating and immobilized alcohol acetyl transferase (atf), one of the key biosynthetic enzymes of the pheromone of Spodoptera littoralis, on agarose beads inside. The system reproduces the last step of the biosynthesis in which the precursor diene alcohol (Z,E)-9,11-tetradecadienol is transformed into the major component (Z,E)-9,11-tetradecadienyl acetate. The scope of this study was to analyze and implement a multilayer, anti-adsorption coating based on layer-by-layer deposition of polyethylenimine/dextransulfate sodium salt (PEI/DSS). The multilayers were composed of two PEI with molecular weights 750 and 1.2 kDa at pH 9.2 or 6.0. Growth, morphology, and stability of the layers were analyzed by ellipsometry and atomic force microscopy (AFM). The anti-adsorption functionality of the multilayer inside the microreactor was validated. The activity of His(6)-(atf) was measured by gas chromatography coupled to mass spectrometer (GC-MS).  相似文献   

Structural and dynamic properties of linker histone H1 binding to DNA     

Dootz R  Toma AC  Pfohl T 《Biomicrofluidics》2011,5(2):24104

Found in all eukaryotic cells, linker histones H1 are known to bind to and rearrange nucleosomal linker DNA. In vitro, the fundamental nature of H1∕DNA interactions has attracted wide interest among research communities-from biologists to physicists. Hence, H1∕DNA binding processes and structural and dynamical information about these self-assemblies are of broad importance. Targeting a quantitative understanding of H1 induced DNA compaction mechanisms, our strategy is based on using small-angle x-ray microdiffraction in combination with microfluidics. The usage of microfluidic hydrodynamic focusing devices facilitates a microscale control of these self-assembly processes, which cannot be achieved using conventional bulk setups. In addition, the method enables time-resolved access to structure formation in situ, in particular, to transient intermediate states. The observed time dependent structure evolution shows that the H1∕DNA interaction can be described as a two-step process: an initial unspecific binding of H1 to DNA is followed by a rearrangement of molecules within the formed assemblies. The second step is most likely induced by interactions between the DNA and the H1's charged side chains. This leads to an increase in lattice spacing within the DNA∕protein assembly and induces a decrease in the correlation length of the mesophases, probably due to a local bending of the DNA.  相似文献   

Chess Instruction Improves Cognitive Abilities and Academic Performance: Real Effects or Wishful Thinking?     

Blanch  Angel 《Educational Psychology Review》2022,34(3):1371-1398

Educational Psychology Review - In accordance with the outcomes from a number of reports, there are cognitive and academic improvements derived from chess learning and chess playing. This evidence,...  相似文献   

Errors of programming and ownership of the robot concept made by trainee kindergarten teachers during an induction training     

Seckel  María José  Vásquez  Claudia  Samuel  Marjorie  Breda  Adriana 《Education and Information Technologies》2022,27(3):2955-2975

Education and Information Technologies - Computational thinking in the educational environment has awaken a rising interest, having been included as part of the curricula from the very beginnings...  相似文献   

Involving Undergraduates in Assessment: Assisting Peers to Provide Constructive Feedback          下载免费PDF全文

Adriana Signorini 《Assessment Update》2014,26(6):3-13

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