Neutrophil CD64 as a sepsis biomarker     

Hoffmann JJ 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2011,21(3):282-290

Neutrophilic granulocytes express their Fcgamma receptor, also known as the CD64 antigen, predominantly when they are activated. This makes neutrophil CD64 a potential biomarker for infection and sepsis. Indeed there is ample literature on the diagnostic utility of neutrophil CD64 in a variety of diseases. This review summarizes the literature on its application as a sepsis biomarker, in adults as well as in neonates and infants. The available data indicate that neutrophil CD64 seems to have high sensitivity (86%) and specificity (87%), but the methodological quality of most studies is questionable. Nevertheless, neutrophil CD64 appears to be a better diagnostic test than traditional hematological assays, C-reactive protein and probably even procalcitonin. Application of neutrophil CD64 in other conditions than sepsis is briefly presented. Finally, future clinical studies are discussed which are needed in order to confirm the diagnostic performance of this promising biomarker.  相似文献   

Children's Increased Emotional Egocentricity Compared to Adults Is Mediated by Age‐Related Differences in Conflict Processing          下载免费PDF全文

Ferdinand Hoffmann  Tania Singer  Nikolaus Steinbeis 《Child development》2015,86(3):765-780

This study investigated the cognitive mechanisms underlying age‐related differences in emotional egocentricity bias (EEB) between children (aged 7–12 years, n = 30) and adults (aged 20–30 years, n = 30) using a novel paradigm of visuogustatory stimulation to induce pleasant and unpleasant emotions. Both children and adults showed an EBB, but that of children was larger. The EEB did not correlate with other measures of egocentricity. Crucially, the developmental differences in EEB were mediated by age‐related changes in conflict processing and not visual perspective taking, response inhibition, or processing speed. This indicates that different types of egocentricity develop independently of one another and that the increased ability to overcome EEB can be explained by age‐related improvements in conflict processing.  相似文献   

Needs of learning disabled adults   总被引：2，自引：0，他引：2  

F J Hoffmann  K L Sheldon  E H Minskoff  S W Sautter  E F Steidle  D P Baker  M B Bailey  L D Echols 《Journal of learning disabilities》1987,20(1):43-52

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Preliminary development of a questionnaire to assess peer athlete mentoring functions: the Athlete Mentoring Questionnaire (AMQ)     

Matt D. Hoffmann  Todd. M. Loughead 《Measurement in physical education and exercise science》2019,23(1):10-25

Using a multiphase approach, the purpose of the present study was to develop a psychometrically sound questionnaire to measure protégés’ perceptions of peer athlete mentoring functions. Phase 1 consisted of three stages: (a) item development, (b) assessment of content validity via think-aloud interviews with peer mentored athletes, and (c) assessment of content validity via an expert rating panel. In phase 2, 377 Canadian National team and varsity athletes who were peer mentored completed an initial 42-item version of the Athlete Mentoring Questionnaire (AMQ) and its factor structure was examined using confirmatory factor analysis (CFA), exploratory structural equation modeling (ESEM), and hierarchical ESEM (ESEM-within-CFA). Measurement invariance testing was also performed in phase 2. The final version of the AMQ contains 34 items that measure six peer athlete mentoring functions. It is hoped that the development of the AMQ will spur research in the emerging area of peer athlete mentoring.  相似文献   

List of Reviewers 2006     

Iven Schad  Regina Roessler  Andreas Neef  Anne Valle Zárate  Volker Hoffmann 《The Journal of Agricultural Education and Extension》2013,19(1):85-87

ASCTRACT

This study aims to analyze the potential and constraints of group-based extension approaches as an institutional innovation in the Vietnamese agricultural extension system. Our analysis therefore unfolds around the challenges of how to foster this kind of approach within the hierarchical extension policy setting and how to effectively shape and enable learning groups. The analysis draws on qualitative data from case studies of five newly established extension groups in Son La province, collected between 2007 and 2008. Content analysis was applied as the main analytical tool. The basic principles of group-based learning approaches are still underdeveloped, mainly due to a non-supportive institutional environment and a command-and-follow mentality. Extension groups suffer from an insufficient distinction between social processes and technical procedures. Finding an appropriate balance between enhancing leadership and supporting collective responsibility is identified as key to sustain groups. The research identified room for adjustments in group-organizational issues since the external institutional environment is hard to change. The particular value of this paper lies in addressing how to organize group-extension approaches in the context of reformed extension systems in a transitional socialist setting.  相似文献   

Book reviews     

John Klapp  Cindy A. Strickland  Patricia A. Haensly  Jess Hoffmann  Christiane Kendrick 《Roeper Review》2013,35(1):47-50

Streznewski, M. K. (1999). Gifted grownups: The mixed blessings of extraordinary potential . New York: John Wiley & Sons (292 pp., $24.95 hb, ISBN‐0–471–29580–9).

Johnson, N.G., Roberts, M.C., & Worell, J., Eds.(1999). Beyond appearance: A new look at adolescent girls . Washington, DC: American Psychological Association (464 pp., ISBN‐1–55798–582–0).

Smutny, J.F. (1998). The young gifted child: Potential and promise, an anthology . Cresskill, NJ: Hampton Press, Inc. (582 pp. $35.00, paperback, ISBN 1–57273–108–7).

Elias, M. J., Zins, J. E., Weissberg, R. P., Frey, K. S., Green‐berg, M. T., Haynes, N. M., Kessler, R., Schwab‐Stone, M. E., & Shriver, T. P. (1997). Promoting social and emotional learning . Alexandria, VA: Association for Supervision and Curriculum Development. (164 pp., $22.95 pb, ISBN‐0–87120–288–3).

Friedman, R. C., & Rogers, K. B. (Eds.). (1998). Talent in context: Historical and social perspectives on giftedness . Washington, DC: American Psychological Association (218 pp., $29.95 Hardback, ISBN 1–55798–493).  相似文献   

Flow experience and positive affect during hypermedia learning     

Udo Konradt  Regina Filip  Svenja Hoffmann 《British journal of educational technology : journal of the Council for Educational Technology》2003,34(3):309-327

In this study positive affective states, experienced by users of a one-hour learning program, in a hypermedia learning environment were assessed. It was expected that a positive mood would occur during learning that would be correlated with high training/learning success. Furthermore, the experience of flow was used to indicate whether the challenges and skills were balanced. The results showed that the users of the training program were put into a positive mood. About a quarter of the users experienced flow. Positive moods were associated with higher training success and positive affect was correlated with total knowledge and content knowledge. An association between flow and training success was not observed. The perceived probability of success did not influence learning but a high perceived probability of success was considered as comparably more pleasant than a low perceived probability of success. The results are discussed in the context of self-directed learning.  相似文献   

Group tests for distinguishing formal from concrete thinkers     

J. A. Rowell  P. J. Hoffmann 《科学教学研究杂志》1975,12(2):157-164

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Non-Didactic, a Culture of Peace, and “Some Cat from Brazil”: A Case Study of Negotiating a Dialogic Curriculum with Incarcerated Girls     

Robert J. Helfenbein  Shanna M. Stuckey  Thomas J. Fennewald  Robert P. Hoffmann 《The Urban Review》2011,43(4):507-527

HIPP Indy is a collaborative effort between the Indiana Department of Correction, the Peace Learning Center, and program facilitators in pursuit of implementing curriculum in peace education, conflict resolution, and self-efficacy with incarcerated, juvenile girls. The Center for Urban and Multicultural Education embarked on a program to partner a reservice teaching candidate with an urban social justice initiative in the hopes of reciprocal benefits for all involved. This study represents both qualitative data from multiple partners in designing and implementing the project, as well as the reflections of the participant-observer and co-author. The authors purport that listening to the stories of the diverse individuals involved in making the program possible offers an opportunity to understand curriculum in-the-making and the complexity of collaborative work. Revealed in this collaboration are new insights into the complexities of working with incarcerated students, attempts at creating a dialogic curriculum, and the ways in which academic discourse (i.e. Freirean praxis) gets translated into practical community-based, social justice work.  相似文献   

OTseeker helps library and allied health professionals to find quality evidence efficiently     

Annie McCluskey  Sally Bennett  Tammy Hoffmann  Leigh Tooth 《Health information and libraries journal》2010,27(2):106-113

Background: Research is essential for evidence‐based practice yet many health professionals do not have enough time to find research. Studies relevant to occupational therapists can be particularly difficult to find. Most search engines are broad and return a large number of irrelevant articles. Occupational Therapy Systematic Evaluation of Evidence (OTseeker) is an occupational therapy database available at http://www.otseeker.com . Developed by Australian occupational therapists, the resource aims to increase access to research and support clinical decision making. This discipline‐specific database contains pre‐appraised information from a variety of sources and decreases the time required to locate best evidence. Objectives: The aims of this paper are to: (i) describe how health librarians can use OTseeker to help allied health students, researchers and practitioners, particularly in occupational therapy, to find quality evidence; (ii) provide a teaching resource for health librarians based around the OTseeker evidence database; and (iii) highlight new features contained on the OTseeker database. Methods: A case study is provided which focuses on searching for evidence on the effectiveness of upper limb rehabilitation after stroke using OTseeker. Conclusion: This paper may increase the knowledge, skills and competencies of health librarians, helping them to access evidence‐based databases, and educate other professionals.  相似文献