Circulating thrombotic and haemostatic components in patients with coronary artery disease     

Kavita K. Shalia  V. K. Shah  M. R. Mashru  S. L. Soneji  J. B. Vasvani  S. S. Payannavar  A. P. Walvalkar  R. A. Mokal  S. M. Mithbawkar  K. V. Kudalkar  A. Abraham  P. K. Thakur 《Indian journal of clinical biochemistry : IJCB》2010,25(1):20-28

The study aimed to analyze the circulating levels of thrombotic and haemostatic components; tissue factor, tissue factor pathway inhibitor, tissue plasminogen activator and plasminogen activator inhibitor-1 in patients with acute myocardial infarction at presentation (Group 1, n=49), unstable angina and Non-ST elevated MI after treatment (Group 2, n=22), stable angina (Group 3, n=18) and healthy individuals (Group 4, n=31). Significant finding was increase in tissue factor not only in Group 1 (2.0 fold, P=0.001), Group 2 (2.2 fold, P=0.015) but also in Group 3 (1.8 fold, P=0.018) as compared to controls. In Group 1 Plasminogen activator inhibitor-1 increased significantly (35.8%, P=0.02). Tissue factor pathway inhibitor and tissue plasminogen activator demonstrated increase in Group 1 of age<40 years while insignificant changes in elder patients. Increased thrombotic and decreased fibrinolytic conditions in acute myocardial infarction patients were observed. Increase TF in stable angina demonstrates procoagulant status in these patients as well.  相似文献   

The Inveterate Tinkerer 15. Miscellaneous Fluid Instabilities     

Chirag Kalelkar 《Resonance》2018,23(7):809-819

In this series of articles, the author discusses various phenomena in fluid dynamics, which may be investigated via tabletop experiments using low-cost or home-made instruments. The fifteenth article in this series demonstrates some fluid instabilities.  相似文献   

Maryam Mirzakhani     

Nikita Agarwal  Riddhi Shah  Geetha Venkataraman 《Resonance》2018,23(3):253-262

The article outlines the life and work of Maryam Mirzakhani — the first and the only female winner of the Fields Medal since its inception in 1936. Mirzakhani is an inspiration to young women around the world, to believe in their own abilities and pursue their academic dreams.  相似文献   

Role of HAMP Genetic Variants on Pathophysiology of Iron Deficiency Anemia     

S. Pandey  S. K. Pandey  V. Shah 《Indian journal of clinical biochemistry : IJCB》2018,33(4):479-482

Hepcidin is a 25-amino acid peptide hormone produced by hepatocytes and plays a key role in body iron metabolism. Hepcidin deficiency is the cause of iron overload in hereditary hemochromatosis, iron-loading anemia, and its excess is associated with anemia of inflammation, chronic disease and iron deficiency anemia (IDA). The aims of this study was to evaluate HAMP gene mutation, namely IVS2 + 1(–G) (c.148–150 + 1del) and Gly71 Asp (c.212G > A (rs104894696) association with iron status in IDA conditions. Our study participants were 500 IDA patients and 550 age and sex-matched healthy controls. Hepcidin, ferritin and CRP analysis was done by ELISA method while ESR analysis was done according to Wintrobe method. CBC analysis was done by auto-analyzer. Two mutations in the HAMP genes were analysed by PCR RFLP method. Among the IDA patients, 7 were heterozygous for Met50del IVS2 + 1(–G) mutation. Nine IDA patients were heterozygous for G71D G–A mutation and homozygous were not identified in both mutations.Controls were showing heterozygous frequency 1.8 and 2.1% of Met50del IVS2 + 1(–G) and G71D G–A mutations respectively. Mutation of HAMP (Met50del IVS2 + 1(–G) and G71D G–A) were clinically associated with IDA and act as modulator of disease.  相似文献   

Trends in private higher education in Australia     

Mahsood Shah  Hai Yen Vu  Sue-Ann Stanford 《Perspectives: Policy and Practice in Higher Education》2019,23(1):5-11

The last decade has witnessed a significant growth of private higher education around the world. The growth included the number of private education providers, and also the growing number of students. While some countries are experiencing trend growth, others are witnessing decline. Some of the reasons for the decline include increased regulation and stringent accreditation and reaccreditation of higher education institutions and courses, government policies to encourage the growth of public universities, and acquisition of small providers by large private education institutions. The growth of private higher education has increased competition, and it has also established collaboration with public institutions. The growth of private higher education has also raised concerns about ethical governance, maintenance of academic standards, and mechanisms to plan, review, and improve educational outcomes. This paper focuses on Australia where despite growth, there is limited research about private higher education. This paper reviews literature on the global growth and decline of private higher education. It then analyses the trends in Australia and possible scenarios for the future of private higher education in the country.  相似文献   

Equal Opportunity Issues in the Context of the National Curriculum: a black perspective     

Sneh Shah 《Gender and education》1990,2(3):309-318

This article examines the context and content of the National Curriculum documentation published so far within the framework of educational debates on the education of black children (black referring to non‐white). In particular it focuses on the interpretation of equal opportunities, the proposed strategies for implementation within the National Curriculum, and the prospects for success because of the other changes brought about by the 1988 Education Reform Act (ERA). The main conclusion is that in some respects more appears to have been achieved than would have seemed possible in the early stages of the debates relating to ERA; on the other hand, there is a probability that an education system that provides true equal opportunities for groups and individuals currently being denied that will remain more of a hope than a reality. The article concludes that equality of opportunity is still a long way off, especially from a black perspective.  相似文献   

Goodbye conflict, hello development? Curriculum reform in Timor-Leste     

Ritesh Shah 《International Journal of Educational Development》2012,32(1):31-38

Motivations to reform curriculum in post-conflict, or post-colonial states are often driven by the need to (re) construct a cohesive and publicly legitimated national identity that is starkly different to that which existed prior. This paper explores the context behind such action in the Timor-Leste (East Timor) and some challenges which policy makers and citizens have wrestled with in developing and implementing the country's first post-independence primary curriculum. The author argues that specific aspects of this new curriculum have effectively alienated and/or divided large segments of its population, despite a desire for the reforms to result in a more inclusive, democratic and distinctly “Timorese” educational system. The assertion is that the desire to institute change rapidly after independence has in fact hampered the ability of the reforms to constructively serve the political and social project of nation building. The paper cautions that education's role in promoting human development, and reducing the triggers of conflict in this country hang in the balance as long as this new curriculum fails to deliver on its aspirations.  相似文献   

US news magazine images of black‐Asian American relationships, 1980–1992     

Michael C. Thornton  Hemant Shah 《The Communication Review》2013,16(4):497-519

During the past 20 years, primarily Latinos and Asians have immigranted to these shores and settled in urban areas. Media sources assert that this influx created particularly problematic relations between blacks and Asian Americans. Using Frame theory and textual analysis, we explored the images newsmagazines produced of this relationship. We found that one frame predominated: the nature of group relations had to do with each group's “essential”; qualities. Within this frame there also appeared four media packages: 1) the nature of the urban space, 2) the role of culture in the quality of relationships, 3) the essential qualities of urban residents and 4) the preeminence of class over race. Analysis of black‐Asian American relationships, while not strictly hegemonic, rarely deviated from accepted critiques. The nature of the coverage constrained understanding to personal shortcomings, while poverty and racial strife were rarely associated with historical and structural factors.  相似文献   

The Impact of Quality on Satisfaction,Revenue, and Cost as Perceived by Providers of Higher Education     

Abhay Shah 《Journal of Marketing for HIGHER EDUCATION》2013,23(2):125-141

Researchers have found a strong relationship between improvements in quality and satisfaction, revenue, and cost. However, no study to date investigates the same for higher education. This study investigates whether institutions of higher education have implemented quality improvement programs, and if so, if the results are similar to what has been observed with firms in the private sector. The study proposes and tests five hypotheses, and findings support four of the five hypotheses, with partial support for the fifth hypothesis. The study finds that implementing quality programs leads to an increase in satisfaction among constituent groups, increase in revenue, and a reduction in costs. The findings also show that increased satisfaction (due to improved quality) also leads to increase in revenue and reduction in costs.  相似文献   

Glimpses of a century-old story     

Jasmine M. Shah 《Resonance》2013,18(4):336-344

The story of Agrobacterium has been widely discussed for over a century. Fridiano Cavara in 1897 first described the occurrence of plant-derived tumors with bacterial origin. Detailed molecular analysis of this microbe accelerated in the last 30 years and it gained worldwide acceptance as a ‘natural genetic engineering tool’. This tool has an interesting history starting from the tumors that it makes, nomenclature, genome, pathogenicity and DNA transfer, to its economic importance. This review is a glimpse of some basic and interesting facts of the unique Agrobacterium.  相似文献