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In the last 30 years, numerous studies have sought to define cultural planning. A common theme that emerges is the emphasis on the need to create a planning process for “placemaking” purposes. However, the definition of what a place is remains vague. Using administrative boundaries, this study draws a framework that formulates an operational definition of place that helps to connect spaces to empirical data about their cultural resources and residents. The focus on administrative boundaries is particularly relevant to understand American cities whose territories have a tangled morphology. Using Geographical Information System, this framework is then applied to assess the current situation in Madison, Wisconsin. The results suggest that the use of this framework could help policy makers to assess the texture of their territory in its administrative, cultural and social dimensions.  相似文献   
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Microfluidics is a relatively novel interdisciplinary research area with broad applications in chemistry, physics, material science, and biology. Despite the rapid growth of the field, students'' exposure to microfluidic technologies is still limited and often insufficient to appreciate the advantages over other commonly used technologies. To this end, we designed a five-day course, “Microfluidics for microbial ecology,” in which students with very different backgrounds learn the basics of microfluidic technologies and sample a range of applications in microbial ecology. The course was created for Master and Ph.D. students interested in applying microfluidics to their research and, therefore, followed an application-oriented approach. The presentation of critical aspects of fluid flow phenomena at the microscale and an outline of the advantages and constraints of the technology provide students with the background to design and perform microfluidics-based experiments. In order to improve the effectiveness of learning in a class with diverse interests and backgrounds, two active learning exercises were implemented. The first comprised the design of an individualized microfluidics experiment in parallel with the lectures: students were guided to apply each module to their personalized application and discuss it in groups. The second was a group experimental activity, in which students jointly set up, performed, analyzed, and presented a microfluidics-based experiment. Given the multidisciplinary teaching context, the course was able to foster common conceptual ground and promote discussion among students. This application-oriented approach built upon experimental activities and in-class discussion is well suited to promote learning in a technology-related subject such as microfluidics.  相似文献   
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This study seeks to explain macrolevel drivers of adolescent fertility rate using a panel data set derived from 17 Latin American countries over a period of 16 years (1997–2012). While many studies of adolescent fertility have focused on individual-level explanations, this study explores whether adolescent fertility rate is correlated to country-level determinants, specifically legislation adoption that guarantees access to school-based sexuality education, emergency contraception, and abortion. After controlling for other country-level factors, we find that countries that have adopted legislation on school-based sexuality education and those with legal access to abortion (under one or more restrictions) have lower adolescent fertility rates.  相似文献   
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The cytology of 130 indeterminate nodules (Thy 3) was retrospectively reviewed according to the British Thyroid Association 2014 classification. Nodules were divided into Thy 3a (atypical features) and Thy 3f (follicular lesion) categories. Histology was available as a reference for 97 nodules. Pre-surgical evaluations comprised biochemical tests, color-Doppler ultrasonography (US), semi-quantitative elastography-US (USE), contrast-enhanced US (CEUS), and mutation analysis from cytological slides. Thyroid malignancy was the final diagnosis for 19% of surgically-treated nodules. No statistically significant difference in the risk of malignancy was found between Thy 3a (26%) and Thy 3f (14%) nodules. Histology of the Thy 3a and Thy 3f nodules showed a higher incidence of Hurtle cell adenomas in Thy 3f (29%) than in Thy 3a (3%) nodules (P=0.01). The only pre-surgical difference concerned the BRAF V600E mutation, which was positive in some Thy 3a but not in any Thy 3f nodules (P=0.04). Receiver-operating characteristic (ROC) analysis was used to obtain cut-off values from US (score), USE (ELX 2/1 strain index), and CEUS (time-topeak index and peak index) data. The cut-off values were similar for Thy 3a and Thy 3f nodules. Data showed that malignancy can be suspected if the US score is >2, ELX 1/2 strain index >1, time-to-peak index >1, and peak index <1. In a sub-group of 24 revised nodules (12 Thy 3a and 12 Thy 3f) with histology as a reference, the diagnostic power of cumulative pre-surgical analysis by means of US, USE, and CEUS showed high positive and negative predictive values (83% and 100%, respectively) for the presence of malignancy in Thy 3a and Thy 3f nodules. In conclusion, in our series of revised Thy 3 nodules, malignancy was low and displayed no significant differences between Thy 3a and Thy 3f categories. The use of cut-offs based on histology as a reference could reduce surgery. Our data support the conviction that, in mutation-negative Thy 3a and Thy 3f nodules, observation should be the first choice when not all instrumental results are suspect.  相似文献   
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The paper identifies “defensive instrumentalism” as a main feature that has characterised New Labour's cultural policies, and which constitutes an important aspect of its legacy. Yet, resorting to instrumental arguments to defend the arts and to make a case for their usefulness is hardly an invention of New Labour. However, in the past, such defensive arguments were built into a more constructive and creative attempt to elaborate a coherent theory of art and an intellectually sophisticated view of the effects of the arts on individual and societies. What the paper argues, then, is that instrumentalism under New Labour has retained its longstanding defensive character, but was deprived of the attendant effort to elaborate a positive notion of cultural value.  相似文献   
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The article argues that current methods for assessing the impact of the arts are largely based on a fragmented and incomplete understanding of the cognitive, psychological and socio-cultural dynamics that govern the aesthetic experience. It postulates that a better grasp of the interaction between the individual and the work of art is the necessary foundation for a genuine understanding of how the arts can affect people. Through a critique of philosophical and empirical attempts to capture the main features of the aesthetic encounter, the article draws attention to the gaps in our current understanding of the responses to art. It proposes a classification and exploration of the factors—social, cultural and psychological—that contribute to shaping the aesthetic experience, thus determining the possibility of impact. The ‘determinants of impact’ identified are distinguished into three groups: those that are inherent to the individual who interacts with the artwork; those that are inherent to the artwork; and ‘environmental factors’, which are extrinsic to both the individual and the artwork. The article concludes that any meaningful attempt to assess the impact of the arts would need to take these ‘determinants of impact’ into account, in order to capture the multidimensional and subjective nature of the aesthetic experience.  相似文献   
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We reproduce the article-level, field-independent citation metric Relative Citation Ratio (RCR) using the Scopus database, and extend it beyond the biomedical field to all subject areas. We compare the RCR to the Field-Weighted Citation Impact (FWCI), also an article-level, field-normalised metric, and present the first results of correlations, distributions and application to research university benchmarking for both metrics. Our analyses demonstrate that FWCI and RCR of articles correlate with varying strengths across different areas of research. Additionally, we observe that both metrics are comparably stable across different subject areas of research. Moreover, at the level of universities, both metrics correlate strongly.  相似文献   
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