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排序方式: 共有104条查询结果,搜索用时 15 毫秒
101.
Hasan Kahveci Cüneyt Tayman Fuat Laloğlu Nazan Kavas Murat Ciftel Osman Yılmaz Esra Laloğlu Abdulah Erdil Hülya Aksoy Salih Aydemir 《Indian journal of clinical biochemistry : IJCB》2016,31(2):231-236
Hemodynamically significant ductus arteriosus (hsPDA) may alter organ perfusion by interfering blood flow to the tissues. Therefore, in infants with hsPDA, hypoxia occurs in many tissues. In this study, we aimed to investigate the diagnostic significance of serum (ischemia-modified albumin) IMA levels as a screening tool for hsPDA, and its relation to the severity of the disease in the preterm neonates. For this purpose, seventy-two premature infants with gestation age <34 weeks were included in the study. Thirty premature infants with hsPDA were assigned as the study group and 42 premature infants without PDA were determined as the control group. Blood samples were collected before the treatment and 24 h after the treatment, and analyzed for IMA levels. IMA levels in the study group (1.26 ± 0.36 ABSU) were found to be significantly higher than control group (0.65 ± 0.12 ABSU) (p < 0.05). In infants with hsPDA, a positive correlation was found between IMA and PDA diameter (ρ = 0.876, p = 0.022), and LA/Ao ratio (ρ = 0.863, p = 0.014). The cut-off value of IMA for hsPDA was measured as 0.78 ABSU with 88.89 % sensitivity, and 90.24 % specificity, 85.71 % positive predictive, 92.5 % negative predictive value [area under the curve (AUC) = 0.96; p < 0.001]. The mean IMA value of the infants with hsPDA before treatment was 1.26 ± 0.36 ABSU, and the mean IMA value of infants after medical treatment was 0.67 ± 0.27 ABSU (p = 0.03). We concluded that IMA can be used as a marker for the diagnosis and monitoring of a successful treatment of hsPDA. 相似文献
102.
Digital broadcast technologies have expanded the virtual capacity of live performing arts venues, but they have also raised concerns about possible cannibalisation of box office revenues. We report the results of a quasi-field experiment involving the Royal National Theatre’s live broadcasts of theatre to digital cinemas in the UK and find that, if anything, live broadcasts generate greater, not fewer, audiences at the theatre. 相似文献
103.
Meysam Ebrahimifar Amir Nili-Ahmadabadi Azim Akbarzadeh Hasan Ebrahimi Shahemabadi Majid Hasanzadegan Hemen Moradi-Sardareh Hassan Madadizadeh Jalal Rezaee-diyan 《Indian journal of clinical biochemistry : IJCB》2017,32(2):230-234
Carboplatin is a chemotherapeutic agent used against various malignancies such as ovarian carcinoma. The aim of this study is to improve the therapeutic efficacy of carboplatin using pegylated liposomal nanocarriers. Nanoparticles were synthesized using thin film hydration technique and characterized for shape morphology, particle size, zeta potential and drug-release properties. In the next step, A2780S and A2780CP ovarian cancer cell lines were used to determine the efficacy of nanodrug by MTT assay. The particle size and zeta potential of nanodrug were measured 244.3 ± 19.6 nm and ?22.9 ± 1.7 mV, respectively. High encapsulation capacity (78.6 ± 3.7 %) confirmed the efficiency of technique. The cytotoxicity results also showed that nanodrug compared to free drug improve the efficacy of carboplatin against both A2780S (P < 0.01) and A2780CP (P < 0.05) cell lines. In conclusion, the findings of our study suggested pegylated liposomal nanocarriers are proper for carboplatin delivery to ovarian cancer cell lines A2780S and A2780CP. 相似文献
104.
Education and Information Technologies - The primary purpose of this study is to examine the effectiveness of presenting animated video prompting (VP) in teaching car wash skills to individuals... 相似文献