Japanese Sports A History     

Allen Guttmann  Lee Thompson  Annette R. Hofmann 《Sportwissenschaft》2003,33(3):334-339

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Multimedia learning     

Linda Lohr  James E. Gall 《Educational technology research and development : ETR & D》2004,52(3):87-90

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What do they know?: An assessment of undergraduate library skills     

Lilith R. Kunkel  Library Director  Susan M. Weaver  Library Director  Kim N. Cook  Library Director 《The Journal of Academic Librarianship》1996,22(6):430-434

This article, which examines variables affecting scores on a test of library skills, finds that the frequency with which students receive assignments requiring library research is the best predictor of a score. The unevenness is students' research skills has implications for bibliographic instruction.  相似文献   

Television coverage of international affairs: William C. Adams (Ed.) Norwood,NJ: Ablex, 1982, 253 pp., $17.50 cloth     

Jin Keon Kim 《Int J Intercult Relat》1984,8(2):221-223

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Modulation of an activity response with associative and nonassociative fear in the rat: A lighting differential influences the form of defensive behavior evoked after fear conditioning     

Godsil BP  Blackmore MA  Fanselow MS 《Learning & behavior》2005,33(4):454-463

Rats confronted with the onset of a light gradient display a transient increase in locomotion called theactivity response (AR) and a dark preference (Godsil & Fanselow, 2004). These experiments demonstrate that the magnitude of the AR can be blunted with Pavlovian fear-conditioning procedures via associative and nonassociative fear. Although manifested in decreased locomotion, the blunted AR effect was not due to increased freezing or immobility behaviors. Instead, rats displayed reduced rearing and an increase in a class of behaviors calledstationary activity. These results suggest that the lighting differential supplied by the cue influences the topography of defensive behavior and reduces the expression of freezing. This procedure provides a means by which to examine learned and unlearned defensive responses to the same stimulus.  相似文献   

Rapid and cost-effective fabrication of selectively permeable calcium-alginate microfluidic device using ��modified�� embedded template method     

Amit Asthana  Kwang Ho Lee  Kyeong-Ohn Kim  Dong-Myung Kim  Dong-Pyo Kim 《Biomicrofluidics》2012,6(1):012821-012821-9

In this paper, we have presented a non-lithographic embedded template method for rapid and cost-effective fabrication of a selectively permeable calcium-alginate (Ca-alginate) based microfluidic device with long serpentine delay channel. To demonstrate the versatility of the presented method, we have demonstrated two different strategies to fabricate serpentine long delay channels without using any sophisticated microfabrication techniques, in formal lab atmosphere. The procedure presented here, also, enables the preparation of a multilayered microfluidic device with channels of varying dimensions, in a single device without using any sophisticated micromachining instrumentation. In addition, we have also qualitatively studied the diffusion of small and large molecules from a Ca-alginate based microfluidic device and proposed a method to effectively control the out-flow of macro biomolecules from the crosslinked Ca-alginate matrix to create a selectively permeable matrix required for various biological and biomimetic applications, as mentioned in the Introduction section of this work.  相似文献   

Gravity-oriented microfluidic device for uniform and massive cell spheroid formation     

Lee K  Kim C  Young Yang J  Lee H  Ahn B  Xu L  Yoon Kang J  Oh KW 《Biomicrofluidics》2012,6(1):14114-141147

We propose a simple method for forming massive and uniform three-dimensional (3-D) cell spheroids in a multi-level structured microfluidic device by gravitational force. The concept of orienting the device vertically has allowed spheroid formation, long-term perfusion, and retrieval of the cultured spheroids by user-friendly standard pipetting. We have successfully formed, perfused, and retrieved uniform, size-controllable, well-conditioned spheroids of human embryonic kidney 293 cells (HEK 293) in the gravity-oriented microfluidic device. We expect the proposed method will be a useful tool to study in-vitro 3-D cell models for the proliferation, differentiation, and metabolism of embryoid bodies or tumours.  相似文献   

Adaptive controller design for spacecraft formation flying using sliding mode controller and neural networks     

Jonghee Bae  Youdan Kim 《Journal of The Franklin Institute》2012,349(2):578-603

A spacecraft formation flying controller is designed using a sliding mode control scheme with the adaptive gain and neural networks. Six-degree-of-freedom spacecraft nonlinear dynamic model is considered, and a leader–follower approach is adopted for efficient spacecraft formation flying. Uncertainties and external disturbances have effects on controlling the relative position and attitude of the spacecrafts in the formation. The main benefit of the sliding mode control is the robust stability of the closed-loop system. To improve the performance of the sliding mode control, an adaptive controller based on neural networks is used to compensate for the effects of the modeling error, external disturbance, and nonlinearities. The stability analysis of the closed-loop system is performed using the Lyapunov stability theorem. A spacecraft model with 12 thrusts as actuators is considered for controlling the relative position and attitude of the follower spacecraft. Numerical simulation results are presented to show the effectiveness of the proposed controller.  相似文献   

Study of C-Reactive Protein and Myocardial Infarction in the Indian Population     

Kavita Shalia  Sudha Savant  Vijaya A. Haldankar  Tulip Nandu  Poonam Pawar  Siddhi Divekar  V. K. Shah  Purvi Bhatt 《Indian journal of clinical biochemistry : IJCB》2012,27(1):74-82

To analyse the association of high sensitivity C-reactive (hsCRP) protein levels and −717A/G single nucleotide polymorphism of CRP with acute myocardial infarction (AMI) in the Indian population. Study population included 100 MI cases wherein 32 patients had experienced previous MI (MI-Group-1), 68 MI cases were recruited at presentation (MI-Group-2) and equal number of age and gender matched healthy individuals. hsCRP levels were determined by ELISA and genotyping of −717A/G was carried out by polymerase chain reaction-based restriction digestion method. The −717A/G genotypes did not influence hsCRP level and their distribution did not differ between groups. However, in the present study hsCRP demonstrated significant correlation with BMI in controls of both the genders and with triglycerides in females of AMI at presentation who otherwise are with low risk profile. Identifying traditional risk factors associated with inflammation may help in controlling the acute event.  相似文献   

A Comparative Study of Bone Scan Findings and Serum Levels of Tumor Marker CA15-3 in Patients with Breast Carcinoma     

Meera S. Ghadge  Purva P. Naik  Bijaynath P. Tiwari  Ruprekha M. Hegde  Tanaji J. Matale 《Indian journal of clinical biochemistry : IJCB》2012,27(1):97-99

Breast cancer is one of the most frequent malignancies in the world. Available staging procedures to detect breast cancer are bone scan, chest X-ray, liver ultrasonography, computerized tomography, estimation of tumor markers like carbohydrate antigen (CA15-3) and carcino embryonic antigen. These procedures are expensive and may not be required in all cases. Out of 70 patients studied, 55 had normal CA15-3 and 15 had elevated levels of Ca15-3. Eight (14.5%) of the 55 patients with normal CA15-3 had abnormal bone scan. Fifteen patients had CA15-3 levels above the normal range and among these 9 (60%) had abnormal bone scan. While prime facie it would appear that a high level of CA15-3 correlate with abnormal bone scan, it is also true that the numbers are small at present and conclusions about the validity of CA15-3 as marker of bone metastasis may be premature.  相似文献