International comparison and educational policy learning: looking north to Finland     

Jennifer Chung 《Compare》2015,45(3):475-479

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Improving the dielectric properties of an electrowetting-on-dielectric microfluidic device with a low-pressure chemical vapor deposited Si3N4 dielectric layer     

Hsien-Hua Shen  Lung-Yuan Chung  Da-Jeng Yao 《Biomicrofluidics》2015,9(2)

Dielectric breakdown is a common problem in a digital microfluidic system, which limits its application in chemical or biomedical applications. We propose a new fabrication of an electrowetting-on-dielectric (EWOD) device using Si₃N₄ deposited by low-pressure chemical vapor deposition (LPCVD) as a dielectric layer. This material exhibits a greater relative permittivity, purity, uniformity, and biocompatibility than polymeric films. These properties also increase the breakdown voltage of a dielectric layer and increase the stability of an EWOD system when applied in biomedical research. Medium droplets with mouse embryos were manipulated in this manner. The electrical properties of the Si₃N₄ dielectric layer—breakdown voltage, refractive index, relative permittivity, and variation of contact angle with input voltage—were investigated and compared with a traditional Si₃N₄ dielectric layer deposited as a plasma-enhanced chemical vapor deposition to confirm the potential of LPCVD Si₃N₄ applied as the dielectric layer of an EWOD digital microfluidic system.  相似文献   

Traceable clonal culture and chemodrug assay of heterogeneous prostate carcinoma PC3 cells in microfluidic single cell array chips     

Jaehoon Chung  Patrick N. Ingram  Tom Bersano-Begey  Euisik Yoon 《Biomicrofluidics》2014,8(6)

Cancer heterogeneity has received considerable attention for its role in tumor initiation and progression, and its implication for diagnostics and therapeutics in the clinic. To facilitate a cellular heterogeneity study in a low cost and highly efficient manner, we present a microfluidic platform that allows traceable clonal culture and characterization. The platform captures single cells into a microwell array and cultures them for clonal expansion, subsequently allowing on-chip characterization of clonal phenotype and response against drug treatments. Using a heterogeneous prostate cancer model, the PC3 cell line, we verified our prototype, identifying three different sub-phenotypes and correlating their clonal drug responsiveness to cell phenotype.  相似文献   

Parameter Estimation in Rasch Models for Examinee‐Selected Items          下载免费PDF全文

Chen‐Wei Liu  Wen‐Chung Wang 《Journal of Educational Measurement》2017,54(4):518-549

The examinee‐selected‐item (ESI) design, in which examinees are required to respond to a fixed number of items in a given set of items (e.g., choose one item to respond from a pair of items), always yields incomplete data (i.e., only the selected items are answered and the others have missing data) that are likely nonignorable. Therefore, using standard item response theory models, which assume ignorable missing data, can yield biased parameter estimates so that examinees taking different sets of items to answer cannot be compared. To solve this fundamental problem, in this study the researchers utilized the specific objectivity of Rasch models by adopting the conditional maximum likelihood estimation (CMLE) and pairwise estimation (PE) methods to analyze ESI data, and conducted a series of simulations to demonstrate the advantages of the CMLE and PE methods over traditional estimation methods in recovering item parameters in ESI data. An empirical data set obtained from an experiment on the ESI design was analyzed to illustrate the implications and applications of the proposed approach to ESI data.  相似文献   

Community‐Based Art Education in China: Practices,Issues and Challenges     

Ning Luo  Chung‐Yim Lau 《The International Journal of Art & Design Education》2020,39(2):445-460

Art educators have been promoting Community‐Based Art Education (CBAE) in schools in order to enhance students’ sense of socio‐cultural identity and contextual learning about local art and culture. It cannot only bridge the gap between the students’ daily lives and the communities and art, but can also enhance their inquiry, discovery and meaning‐making abilities. In China, the community‐based approach plays a significant role in the National Standards for Visual Arts, and Chinese art educators have been applying CBAE in school art education for decades. However, Western art educators are still unfamiliar with the issues, practices and challenges related to CBAE in China owing to language constraints. In light of the above, this article aims to initiate a dialogue between Western and Chinese CBAE researchers through discourse and discussions on the main issues related to CBAE in Chinese art education. It outlines current practices of, and issues related to, CBAE from the perspective of Chinese art education. It also discusses the three major challenges to the implementation of CBAE in China, namely the conflict between indigenous knowledge and official knowledge in the school art curriculum, lack of motivation among teachers, and neglect of context in the practice of local art in schools. It is hoped that this article it will enrich our overall knowledge of CBAE and contribute to the understanding of CBAE from a global perspective.  相似文献   

A Cognitive Learning Account of the Avoidance,Omission and Exaggerated Phenomena and Expressions in Young Adolescents’ Drawings of the Human Figure in the Visual Culture Art Education Context     

Chung‐yim Lau 《The International Journal of Art & Design Education》2020,39(3):686-703

It is common in the everyday art class to find many examples of avoidance, omission and exaggeration in young adolescents’ depictions of the human figure. When students depict sophisticated human images, they make every effort to avoid the difficult parts, and some students tend to exaggerate the size or distort the shape of the human image. Art educators see these types of behaviour and modes of expression as unnatural, and claim that they may hinder the development of the creativity of young adolescents. Relevant discussions in the literature from a psychological perspective are mainly concerned with the negative impact of such behaviour and modes of expression on the formation of young adolescents’ identities. However, in the context of popular visual culture, the findings of recent studies on young adolescents’ comic drawings have suggested that when young adolescents draw comic characters, they use their everyday life experiences in their drawings. This article reports on a five‐year qualitative longitudinal study conducted in a Hong Kong secondary school. The aim of the study was to deepen our understanding of this behaviour on the part of adolescents in art classes. The findings of the study confirmed the view that these aspects should be interpreted from a cognitive learning perspective. It is suggested that art educators reconsider these types of behaviour and modes of expression as a potential means for improving secondary students’ learning of the art of popular visual culture.  相似文献   

Long-term inhibition of Na+/H+ exchange attenuates cardiac remodeling after myocardial infarction in rats     

Xia Qin-gui  Oliver Chung  Heidi Spitznagel  Thomas Unger 《浙江大学学报(A卷英文版)》2001,2(4):439-444

Objective: In addition to pH regulation, Na⁺/H⁺ exchange (NHE) has been shown to facilitate cell growth and proliferation. However, the effects of long-term inhibition of Na⁺/H⁺ exchange on cardiac structural and functional remodeling post myocardial infarction (MI) are still controversial. The present study was therefore carried out to further investigate the effects of long-term treatment with cariporide, a specific inhibitor of NHE-1, on cardiac remodeling after MI in rats; Methods: Male Wistar rats that underwent coronary ligation were randomly selected for cariporide treatment starting 6 h after induction of MI or no treatment. Treatment was continued up to 6 weeks post MI, after which, the arterial, venous and left ventricular catheters were chronically implanted. Twenty-four h later, after hemodynamic signals were recorded in conscious rats, they were sacrificed and hearts were taken out for morphological examinations; Results: Cariporide treatment decreased the heart weight and heart weight to body weight ratio (bothP<0.05), decreased left ventricular end-diastolic pressure (P<0.001), improved myocardial contractility (dP/dt _max) (P<0.05) and tended to increase the survival of treated rats compared to that of untreated infarct rats; Conclusion: The results of the present study indicate that the long-term inhibition of NHE with cariporide can attenuate cardiac structural remodeling and improve left ventricular dysfunction in infarcted rats, and suggest that Na⁺/H⁺ exchange inhibition could be an effective therapeutic strategy for myocardial infarction-induced heart failure.  相似文献   

Gender Differences in Social Mastery Motivation and Its Relationships to Vocabulary Knowledge,Behavioral Self-Regulation,and Socioemotional Skills     

Wing-kai Fung  Kevin Kien-hoa Chung  Rebecca Wing-yi Cheng 《Early education and development》2019,30(2):280-293

The present study investigated gender differences in social mastery motivation, vocabulary knowledge, behavioral self-regulation, and socioemotional skills and examined the relationships among this knowledge and these skills by gender. Participants were 134 Chinese children (68 boys, M age = 3.80; 66 girls, M age = 3.89) and their parents recruited through local kindergartens’ parent groups. The children were administered measures of social mastery motivation, vocabulary knowledge, behavioral self-regulation, and nonverbal intelligence. Parents reported their education level and children’s socioemotional skills. Research Findings: Results revealed that boys exhibited more social mastery interactions than girls, and girls showed better behavioral self-regulation and socioemotional skills than boys. Girls with higher social mastery interaction frequency demonstrated better vocabulary knowledge and socioemotional skills, whereas boys with higher social mastery interaction frequency showed lower behavioral self-regulation. Boys, who showed more positive affect during social mastery interactions, tended to have better expressive vocabulary, which facilitated their behavioral self-regulation. Practice or Policy: Findings highlight social mastery motivation as a potential factor that facilitates children’s early development, but it may contribute to boys and girls in different ways.  相似文献   

Performance effects of partnership between manufacturers and suppliers for new product development: the supplier’s standpoint     

Seungwha Chung  Gyeong Mook Kim 《Research Policy》2003,32(4):587-603

This study analyzes the effects of supplier involvement in a manufacturer’s new product development on the supplier’s financial performance, innovation, and product quality with data from 128 suppliers in the Korean automobile and electronics industries. The results indicate that a higher level of supplier’s involvement positively influences innovation and financial performance. The results generally indicate that a higher level of supplier involvement, especially in the form of involvement in the design stage significantly increases suppliers’ innovation and cash-flow rate. However, the positive effect of supplier involvement on quality was observed only in the electronics industry.  相似文献   

The effect of multimedia instruction for Chinese learning     

Chung‐ping Lee  Chung‐wei Shen 《Learning, Media and Technology》2008,33(2):127-138

In Taiwan, lectures are commonly used for younger students to learn their own language, which is traditional Chinese. Passively listening to lectures has led to this group of students making such mistakes as forgetting strokes and word meanings, combining phrases to create incomprehensible blurs of information, and switching radicals with phonetic characters. Thus, the rationale of this study is that better and longer lasting Chinese learning results will occur when a combination of well‐designed texts, audio, graphics, animation, and hands‐on practice are employed. A multimedia system with computer‐based courseware in combination with added, assistive technologies including sound equipment, digital boards, and pens was developed based on this rationale. This study used a treatment group who used the system and a comparison group who received lectures. The subjects were 41 second graders in a southern city in Taiwan and all of them received the same pretest, immediate posttest, and the delayed posttest. Even though some of the differences between the two groups did not reach statistical significance, the results revealed that the treatment group consistently performed better than the comparison group in almost all the areas of competencies in both posttests.  相似文献