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11.
Rajat Arora 《Performance Improvement》2016,55(1):23-35
This article describes a performance improvement project undertaken in the manufacturing unit of a multinational company in India that specializes in the business of engineering, procurement, and construction (EPC). The article includes a brief introduction to the company's business (leaving out the name of the company due to a clause of confidentiality). The objective of the article is to describe a set of performance problems and how various performance theories, models, and tools were used to identify root causes and to implement design solutions for improvement. The article describes how the author as an internal consultant employed various consulting principles to establish a strong platform of understanding and to build a partnership with the clients. In addition, the different stages used in analyzing the problem, applying performance models, and designing solutions are presented. The article concludes with the author's sharing his personal experiences and the feedback he received from project stakeholders. 相似文献
12.
Alex Livy Sayhean Lye Chahil K. Jagdish Nurul Hanis Velapasamy Sharmila Lian Wee Ler Bagali Pramod 《Indian journal of clinical biochemistry : IJCB》2012,27(1):28-33
Buccal cell usage has been shown by many to be a cost effective and safe method to isolate DNA for various biological experiments
especially large epidemiological studies (Garcia-Closas et al. Cancer Epidemiol Biomarkers Prev 10:687–696, 2001). Non-invasive DNA collection methods are preferred over phlebotomy in order to increase study participation and compliance
in research centers and for sick patients in hospital settings. There have been conflicting reports about the methodology
and results obtained from using buccal DNA. It is not very clear if phlebotomy can be confidently replaced by buccal cell
DNA. It is often left for the user to take an intelligent decision. To address this issue, we compared the performance of
buccal and blood DNA from same subjects in a genotyping experiment and this paper reports the results. Cotton swab derived
buccal cells were scraped from the inner side of cheeks from 16 subjects, and blood was also drawn from the same 16 subjects
participating in a genotypic association study of a lipid disease. The DNA quality was assessed by resolving on agarose gels,
checking purity (A260/A280) and finally by microarray hybridization. This study showed that DNA degradation affects the total
yield and performance of the buccal DNA when compared to the blood DNA in microarray based genotyping. Genotyping results
can be seriously compromised if care is not taken to check the quality and yields of such specimens. 相似文献
13.
ABSTRACT‘Disability’; the ‘D’ word generally speaks its own meaning, as anyone who is different from others in terms of physical and mental impairment. There are various types of disabilities; broad categories such as physical and communication disability, mental illness and mental retardation, learning disabilities and so forth. In this article, an attempt has been made to describe the term ‘visual impairment’ which falls under the category of physical and communication disability. The next section of the article presents activities of the National Institute for the Visually Handicapped, Dehradun, India to make the visually impaired self-sufficient and to recognize the role played by the Institute in disseminating information to them. 相似文献
14.
Payal Arora 《亚洲交流杂志》2013,23(4):337-352
In designing digital literacy content for marginalized demographics, we need to garner local resources to structure engaging and meaningful media experiences. This paper examines the socio-cognitive implications of a novel edutainment product in rural India on learning, stemming from an e-development initiative funded by Hewlett-Packard. This product encapsulates a multiplicity of media forms: text, audio and visual, with social-awareness folk themes endemic to the locality. It uses the karaoke ‘same language subtitling’ feature that won the World Bank Development Marketplace Award in 2002 due to its simple yet innovative application that has proven to have an impact on reading skills. The product strives to combine cultural regeneration, value-based education, incidental literacy and language practice through entertainment. The paper investigates how this product addresses engagement and empowerment simultaneously, based on elements such as emotional appeal, multimodal stimulation, interactivity, contextual content and local representation. This is useful for practitioners and scholars interested in the design of novel edutainment content for international, underrepresented demographics. 相似文献
15.
Kavita K. Shalia Manoj R. Mashru Jagdish B. Vasvani Rajashree A. Mokal Shilpa M. Mithbawkar Priti K. Thakur 《Indian journal of clinical biochemistry : IJCB》2009,24(4):388-397
Hypertension causes complications such as coronary atherosclerosis and thrombosis wherein inflammatory factors play significant
role. In the present study inflammatory molecules such as cell adhesion molecules (CAMs); endothelial (E)-selectin, platelet
(P)-selectin, intercellular CAM-1 (ICAM-1), vascular CAM-1 (VCAM-1) and platelet endothelial CAM-1 (PECAM-1) were analysed
in subjects newly diagnosed with hypertension with no secondary cause against normotensive healthy individuals. In each group
57 subjects were recruited and soluble (s) levels of CAMs were analysed by ELISA. As compared to controls median of sE-selectin
(49.2%, P=0.001), sP-selectin (54.3%, P=0.001), and sICAM-1 (18.9%, P=0.012) were significantly elevated in hypertensive subjects.
Significant negative correlation was observed of sP-selectin (spearman rank correlation coefficient (rs) =−0.345, p=0.027)
and sPECAM-1 (rs =−0.446, p=0.003) with age in hypertension group. Hypertension may increase expression of certain CAMs while
younger hypertensives in addition are also at increased risk of atherothrombosis. 相似文献
16.
Ravjit Kaur Sabharwal Parduman Singh M. M. Arora B. L. Somani Vivek Ambade 《Indian journal of clinical biochemistry : IJCB》2008,23(1):71-75
The prevalence of microalbuminuria was assessed in 174 albustix negative hypertensive patients by estimating albumin in the
morning random urine samples by immunoturbidimetric method within four hours of voiding of urine. The urine samples were not
stored and collected without any preservatives. The urinary albumin was calculated in terms of ratio with respect to urinary
creatinine and expressed as albumin creatinine ratio (mg/g). Out of 174 albustix negative hypertensives, 58 (33.3%) patients
were found to have microalbuminuria. The prevalence of microalbuminuria in males and females was found to be 34% and 30.7%
respectively. No correlation was found between the Body Mass Index (BMI) and albumin excretion (r2 = 0.0271) and between duration of hypertension and urinary albumin excretion (r2 = 0.0042). Prevalence of microalbuminuria in nonsmokers and non-alcoholic hypertensives was 20%. The prevalence in alcoholics,
smokers and both smokers and alcoholics was found to be 35%, 42% and 41% respectively. The high prevalence of microalbuminuria
than the various reported studies on the subject demands establishment of a screening programme for microalbuminuria, implementation
of specific intervention methods and education of hypertensive patients about the consequences of smoking and alcohol on possible
involvement of renal system. 相似文献
17.
H. K. Jassi A. Jain Sarika Arora R. Chitra 《Indian journal of clinical biochemistry : IJCB》2010,25(2):201-207
Soy isoflavones and soy proteins are being considered as possible alternatives to postmenopausal hormone replacement therapy.
This study was undertaken to evaluate effects of these two preparations on symptoms and lipid profile in postmenopausal women.
The study was done in 75 postmenopausal women with FSH levels = 30 mIU/ml. These women were randomly divided into 3 groups
(n=25). Study group I was given soy proteins 30gm/day containing 60 mg soy isoflavones. Study group II was given soy isoflavones
(60 mg/day). The control group was given casein protein 30 gm/day. The menopausal symptoms were assessed by Kupperman Index.
Fasting blood samples were analyzed for serum lipid profile, apolipoprotein A1 and B, Leutenizing Hormone (LH) and Follicle-Stimulating
Hormone (FSH) at the beginning of therapy, 4 and 12 weeks after initiation of therapy. A highly significant improvement in
postmenopausal symptoms was observed in both the study groups. A highly significant improvement was seen in serum lipid profile
and Apolipoprotein A1 and B in women taking soy proteins whereas women taking soy isoflavones demonstrated significant improvement
in serum triglycerides only. Both soy proteins and soy isoflavones are helpful in alleviating postmenopausal symptoms but
soy proteins offer a greater health advantage due to their beneficial effect on serum lipid profile. 相似文献
18.
Tiny Arora 《Pastoral Care in Education》2013,31(3):11-15
James Park, the director of Antidote, criticizes those who believe that the most important task of education is to develop cognitive abilities, without any particular regard for emotional development. He argues that such an approach leaves individuals ill equipped to engage with the challenges that life throws in their path. He feels that, in spite of the recognition in the new National Curriculum Guidance of the significance of emotional processes on learning, government policy as a whole does not always appear to acknowledge this. In his view, ‘feeling and thinking, are engaged in a continuous dance. Individuals who can gracefully glide between the two modes bring energy to the task of learning and thinking’. He goes on to outline the key competencies that individuals require to achieve this, and suggests that these are most effectively achieved through dialogue ‘talking together in ways that allow individuals to understand the thoughts, feelings and values of each other’. The paper concludes with an explanation of the work and aims of Antidote. 相似文献
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20.
Neelima Verma Shaloo Kapoor Deepa Rao Siddhartha Sharma Anita Arora 《Indian journal of clinical biochemistry : IJCB》2014,29(1):107-111
Procalcitonin (PCT) is an innovative and highly specific marker for diagnosis of clinically relevant bacterial infection and sepsis. PCT supports early diagnosis and Clinical decision making. A retrospective study of two classical cases of neutropenic sepsis with elevated PCT levels in cardiac ICU was done. PCT was analyzed using Elecsys Brahms PCT kit. Serum PCT levels <0.5 ng/ml and ANC <1,000/mm3 was taken as cutoff. The first patient had initial high levels of PCT 100 ng/ml, TLC 13,600/mm3 and ANC 12,250/mm3. It was followed by drop with subsequent rise in PCT levels and drop in TLC 1,000/mm3 and ANC 70/mm3. The second patient had normal PCT 0.116 ng/ml, TLC 5,600/mm3 and ANC 4,420/mm3 levels followed with sharp increase in all the values with subsequent drop in TLC 2,000/mm3 and ANC 880 cells/mm3. Both the patients died of neutropenic sepsis with multiorgan failure. The case reports showed the correlation of PCT with TLC and ANC levels in predicting the mortality of patients with neutropenic sepsis in cardiac ICU. 相似文献