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Julien Caunter Stanley J. Solomon Jerry Lewis William Bayer Alan Rosenthal 《Communication Booknotes Quarterly》2013,44(4):4-6
Julien Caunter's How to Make Movie Magic in Amateur Films (Philadelphia: Chilton Books, 1971---price not known) Stanley J. Solomon The Film Idea (New York: Harcourt, Brace, Javanovich, March 1972---$4.95 paper) Jerry Lewis' The Total Filmmaker (New York: Random House, 1971---$6.95) William Bayer's Breaking Through, Selling Out, Dropping Dead, and Other Notes on Film Making (New York: Macmillan, 1971---$5.95) Alan Rosenthal (ed.) The New Documentary in Action: A Casebook in Film Making (Berkeley: University of California Press, 1971---$11.95) 相似文献
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BackgroundPuberty is a critical time in the development of overweight and obesity. The aim of this study was to examine relationships between measures of adiposity, cardiovascular fitness, and biomarkers of cardiovascular disease risk in adolescents.MethodsIn a cross-sectional study design, 129 girls and 95 boys aged 12.9–14.4 years at various stages of puberty were included, along with their mothers (n = 217) and fathers (n = 207). Anthropometric assessments of adiposity were made, along with cardiovascular physical fitness, using the 20-m shuttle run test, and biomarkers associated with cardiovascular risk, including glucose, insulin, triglyceride, fibrinogen, and C-reactive protein (CRP) concentrations.ResultsWaist-to-height ratio values were similar in boys and girls and correlated positively with diastolic blood pressure, insulin, triglyceride, fibrinogen, and CRP concentrations, and inversely with cardiovascular fitness scores. Skinfold thickness measurements were higher in girls. High-molecular-weight adiponectin concentrations were lower in boys than girls, particularly in late puberty, and CRP levels were higher. Cardiovascular fitness, maternal body mass index (BMI), and paternal BMI contributed independently to the variance in waist measurements in girls and boys. Gender, triceps skinfold thickness, and weight-to-height ratio, but not parental BMI, contributed independently to the variance in cardiovascular fitness.ConclusionThere is a relationship between measures of adolescent adiposity and parental weight that involves factors other than cardiovascular fitness. Adolescent boys have relatively more abdominal fat than girls and a tendency to have a proinflammatory profile of biomarkers. These observations suggest that family and social environmental interventions are best undertaken earlier in childhood, particularly among boys. 相似文献
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Julien Marchalot Jean-Fran?ois Chateaux Magalie Faivre Hichem C. Mertani Rosaria Ferrigno Anne-Laure Deman 《Biomicrofluidics》2015,9(5)
Enrichment of rare cell populations such as Circulating Tumor Cells (CTCs) is a critical step before performing analysis. This paper presents a polymeric microfluidic device with integrated thick Carbon-PolyDimethylSiloxane composite (C-PDMS) electrodes designed to carry out dielectrophoretic (DEP) trapping of low abundance biological cells. Such conductive composite material presents advantages over metallic structures. Indeed, as it combines properties of both the matrix and doping particles, C-PDMS allows the easy and fast integration of conductive microstructures using a soft-lithography approach while preserving O2 plasma bonding properties of PDMS substrate and avoiding a cumbersome alignment procedure. Here, we first performed numerical simulations to demonstrate the advantage of such thick C-PDMS electrodes over a coplanar electrode configuration. It is well established that dielectrophoretic force (FDEP) decreases quickly as the distance from the electrode surface increases resulting in coplanar configuration to a low trapping efficiency at high flow rate. Here, we showed quantitatively that by using electrodes as thick as a microchannel height, it is possible to extend the DEP force influence in the whole volume of the channel compared to coplanar electrode configuration and maintaining high trapping efficiency while increasing the throughput. This model was then used to numerically optimize a thick C-PDMS electrode configuration in terms of trapping efficiency. Then, optimized microfluidic configurations were fabricated and tested at various flow rates for the trapping of MDA-MB-231 breast cancer cell line. We reached trapping efficiencies of 97% at 20 μl/h and 78.7% at 80 μl/h, for 100 μm thick electrodes. Finally, we applied our device to the separation and localized trapping of CTCs (MDA-MB-231) from a red blood cells sample (concentration ratio of 1:10). 相似文献
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Matthias Gilgien Jörg Spörri Julien Chardonnens Josef Kröll Philippe Limpach Erich Müller 《Journal of sports sciences》2015,33(9):960-969
In the sport of alpine skiing, knowledge about the centre of mass (CoM) kinematics (i.e. position, velocity and acceleration) is essential to better understand both performance and injury. This study proposes a global navigation satellite system (GNSS)-based method to measure CoM kinematics without restriction of capture volume and with reasonable set-up and processing requirements. It combines the GNSS antenna position, terrain data and the accelerations acting on the skier in order to approximate the CoM location, velocity and acceleration. The validity of the method was assessed against a reference system (video-based 3D kinematics) over 12 turn cycles on a giant slalom skiing course. The mean (± s) position, velocity and acceleration differences between the CoM obtained from the GNSS and the reference system were 9 ± 12 cm, 0.08 ± 0.19 m · s-1 and 0.22 ± 1.28 m · s-2, respectively. The velocity and acceleration differences obtained were smaller than typical differences between the measures of several skiers on the same course observed in the literature, while the position differences were slightly larger than its discriminative meaningful change. The proposed method can therefore be interpreted to be technically valid and adequate for a variety of biomechanical research questions in the field of alpine skiing with certain limitations regarding position. 相似文献
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The rapid rise of MOOCs (Massive Open Online Courses) signals a shift in the ways in which digital teaching and learning are engaged in and understood. Drawing upon a comprehensive search of nine leading academic databases, this paper examines the initial phase of MOOC scholarship (2009–2013), and offers an analysis of these empirical studies that conceptualizes themes in MOOC scholarship and locates them within a chronological framework. Two key phases of scholarship about MOOCs are identified, each with associated research imperatives and themes. Phase One: Connectivist MOOCs, Engagement and Creativity 2009–2011/2012. Themes of Phase One include: development of Connectivism as a learning theory, and technological experimentation and innovation in early cMOOCs. Phase Two: xMOOCs, Learning Analytics, Assessment, and Critical Discourses about MOOCs 2012–2013. Themes of Phase Two include: the rise of xMOOCs, further development of MOOC pedagogy and platforms, growth of learning analytics and assessment, and the emergence of a critical discourse about MOOCs. 相似文献
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We discuss the ability to perform fluorescent immunocytochemistry, following cell fixation, using a microfluidic array of primary, nonadherent, single CD34+ stem cells. The technique requires small cell samples and proceeds with no cell loss, making it well-suited to monitoring these rare patient-derived cells. The chip allows us to correlate live cell dynamics across arrays of individual cells with post-translational modifications of intracellular proteins, following their exposure to drug treatments. Results also show that due to the microfluidic environment, the time scale of cell fixation was significantly reduced compared to conventional methods, leading to greater confidence in the status of the protein modifications studied. 相似文献
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A Canadian national survey of 788 library staff doing instructional work revealed that most participants expected to be doing some teaching in their workplaces, and the largest proportion of participants have been teaching for more than 10 years. Most instruction continues to take the form of short presentations to groups of learners. On the whole, preparatory experiences are informal—on-the-job experience, reading professional literature, and attending workshops. The majority of respondents identify instructional work as integral to their professional identity, but nearly one-third see this work as a duty or expectation, and a small proportion view it as an imposition. The study results have implications for design of programs that prepare library staff for the workplace, and for library managers who need to support effective instructional practice. 相似文献
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The concept of spreading activation describes how retrieval of one memory cues retrieval of other memories that are associated with it. This study explored spreading activation in 6‐, 12‐, and 18‐month‐old infants. Infants (n = 144) learned two tasks within the same experimental session; one task, deferred imitation (DI), is typically remembered longer than the other task, visual recognition memory (VRM). At all ages, retrieval of the DI memory facilitated retrieval of the VRM memory, but the conditions under which this spreading activation occurred changed as a function of age. The implications of these findings are discussed in relation to the development of mnemonic networks during infancy and the value of studying infants for our understanding of memory more generally. 相似文献
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