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81.
[目的]探索医学期刊组织专题的有效途径,为国内医学期刊提供借鉴与参考。[方法]以《放射学实践》杂志为例,介绍其通过与协办单位合作、及时报道重大科研成果、围绕突发公共卫生事件等多种方式进行专题组稿的经验和体会;比较、分析专题论文和非专题论文的质量。[结果]《放射学实践》近3年成功组织了22个专题,极大地扩大了本刊在业内的影响。专题论文的篇均被引频次和篇均下载量均明显高于非专题论文。[结论]医学期刊编辑应该结合自身杂志特点,充分发挥积极性和主动性,勇于探索,敢于创新,不断开拓专题组稿的新方法和新形式,为提高期刊质量不懈努力。  相似文献   
82.
抗生素耐药性的来源与控制对策   总被引:7,自引:0,他引:7       下载免费PDF全文
抗生素除了大量用于人类疾病的治疗外,还作为饲料添加剂被广泛应用于动物养殖业。微生物的抗生素耐药性就是指微生物能够在抗生素存在的情况下生长和繁殖。抗生素耐药性是环境微生物固有的,即所谓的内在抗性,但是人类大量使用抗生素带来的抗生素抗性基因的扩散和传播普遍存在,且已开始威胁到全球人群的健康。微生物对抗生素的抗性主要有3个机制:(1)抗生素的外排;(2)抗生素的降解或修饰;(3)抗生素作用位点的保护。大量研究表明,抗生素的使用和抗生素抗性的蔓延呈现良好的相关性,而且环境微生物的抗性可以通过基因横向转移向人类致病菌扩散,最终可能导致超级细菌的爆发,直接影响人类健康。为了应对全球性的抗生素抗性问题,必须加强:(1)全球抗生素使用和环境排放的监管政策和管理体系;(2)建立快速和透明的抗生素耐药性监测体系,使其涵盖医院、养殖业、污水处理厂等;(3)建立抗生素药物创新基金,通过政府和企业的联合,加快新型药物的研制;同时加强知识产权保护,使新药创制走上可持续之路;(4)加强抗生素耐药性相关的基础与应用研究,包括耐药性发生和传播的生态学机制,消除和缓解耐药性发生和传播的环境技术及其系统解决方案等,包括改进污水处理厂的处理工艺,削减出水中抗性基因和抗性菌的比例;(5)加强抗生素耐药性的科普宣传,提高全社会对耐药性的认知能力,从而在源头上有效控制抗生素在农业和医疗方面的滥用及其环境污染。  相似文献   
83.
Electroosmotic flow (EOF) with two or more fluids is commonly encountered in various microfluidics applications. However, no investigation has hitherto been conducted to investigate the hysteretic or flow direction-dependent behavior during the displacement flow of solutions with dissimilar ionic species. In this investigation, electroosmotic displacement flow involving dissimilar ionic solutions was studied experimentally through a current monitoring method and numerically through finite element simulations. The flow hysteresis can be characterized by the turning and displacement times; turning time refers to the abrupt gradient change of current-time curve while displacement time is the time for one solution to completely displace the other solution. Both experimental and simulation results illustrate that the turning and displacement times for a particular solution pair can be directional-dependent, indicating that the flow conditions in the microchannel are not the same in the two different flow directions. The mechanics of EOF hysteresis was elucidated through the theoretical model which includes the ionic mobility of each species, a major governing parameter. Two distinct mechanics have been identified as the causes for the EOF hysteresis involving dissimilar ionic solutions: the widening/sharpening effect of interfacial region between the two solutions and the difference in ion concentration distributions (and thus average zeta potentials) in different flow directions. The outcome of this investigation contributes to the fundamental understanding of flow behavior in microfluidic systems involving solution pair with dissimilar ionic species.  相似文献   
84.
During the Japanese occupation of British Malaya and Southeast Asia from the years 1942 to 1945 there were reports of POWs being allowed to play cricket, football, rugby and basketball, as told by Kevin Blackburn in The Sportsmen of Changi published in 2012. This research about the sporting lives of a Governor and male European internees at Singapore's Changi prison is likely to be first detailed research on this topic. The authors depended mainly on four published diaries and 262 issues of the men's camp newspaper, Changi Guardian, to account for the male internees' casual and competitive cricket, football, hockey, volleyball, badminton, tennis and boxing matches that were played during internment. The Japanese Military Administration allowed the male internees to organize their daily lives and play games that they indulged in during the pre-War period as the British dominated the Singapore Cricket Club, Penang Cricket Club and Perak Club. The internees were able to play the various games and matches in spite of the limited food and sparse facilities. Many of the cricket and football games that were played were organized as inter-state, inter-club or league matches. These games were played with improvized equipment and rules.  相似文献   
85.
A novel microfluidic device which consists of two stages for particle focusing and separation using a viscoelastic fluid has been developed. A circular capillary tube was used for three-dimensional particle pre-alignment before the separation process, which was inserted in a polydimethylsiloxane microchannel. Particles with diameters of 5 and 10 μm were focused at the centerline in the capillary tube, and the location of particles was initialized at the first bifurcation. Then, 5 and 10 μm particles were successfully separated in the expansion region based on size-dependent lateral migration, with ∼99% separation efficiency. The proposed device was further applied to separation of MCF-7 cells from leukocytes. Based on the cell size distribution, an approximate size cutoff for separation was determined to be 16 μm. At 200 μl/min, 94% of MCF-7 cells were separated with the purity of ∼97%. According to the trypan blue exclusion assay, high viability (∼90%) could be achieved for the separated MCF-7 cells. The use of a commercially available capillary tube enables the device to be highly versatile in dealing with particles in a wide size range by using capillary tubes with different inner diameters.  相似文献   
86.
随着人类社会的发展,在高等教育中加强环境教育成为高等教育发展的趋势。传统的教育思想已不能适应社会发展的需要,必须要有新的适应社会发展需要的教学理念出现。本文结合自己环境教育教学实践经验并借鉴他人的经验,采用案例——实践教学和研究——合作学习的理念与方式,进行了教学改革试验,收到了初步成效。  相似文献   
87.
模糊限制语在交际过程中具有不可或缺的地位。拟就模糊限制语的定义、分类以及在政治语篇中的语用功能做出分析,得出结论:政治语篇中,模糊限制语具有保全面子,增强说服力,赢取认同与支持,避免承担责任,进行自我保护等人际功能。  相似文献   
88.
乔霞 《鸡西大学学报》2011,11(6):119-120
通过黄巾起义发家的曹操,在不断地战争中有了统一天下的愿望。由于曹操的谋略、品行和军事才能,在其周围聚集了一批文臣武将,在他们的协助下,曹操的队伍不断地发展壮大,形成了独立的政权。建安元年,曹操建都许昌,以许昌为基点展开了统一天下的一系列军事征伐。曹魏政权对许昌也进行了一定的开发,一方面促进了许昌经济的发展,另一方面也为曹魏统一北方奠定了基础。  相似文献   
89.
The purpose of this research is to investigate the factors that affect undergraduates' behavioral intention to use digital library among the private universities in Malaysia. The target respondents are undergraduates from Malaysian private universities. Questionnaires were distributed among 500 undergraduates through either online or face-to-face method. Reliability test, normality test, Pearson Correlation Coefficient analysis, and Multiple Linear Regression (MLR) were carried out for data analysis. Performance expectancy, social influence, facilitating conditions, hedonic motivation, habit, and information quality had a positive and significant association with behavioral intention to adopt a digital library except for effort expectancy. This research successfully reinforced that the inspiration to ameliorate Unified Theory of Acceptance and Use of Technology 2 (UTAUT 2) by synthesis of Information Systems Success Model (ISSM). This proposed framework with a combination of ISSM and UTAUT 2 has enhanced the fitness of UTAUT 2. Universities that have yet to implement digital library can comprehend undergraduates' needs better by considering all the significant factors to develop a digital library. The universities with the digital library may also notice the important features of the existing digital library that should be maintained and upgraded constantly so that they can fulfil undergraduates' requirements.  相似文献   
90.
互联网作为当代获取信息的基本手段之一,不仅仅作为通信工具而存在,更重要的是时刻影响着当代大学生的行为处事方式、世界观、人生观、价值观乃至日常生活。然而互联网也是一把“双刃剑”,在给大学生们的生活带来便捷的同时,也占据了大学生的大量时间,在虚拟的世界当中思想处于悬空状态,心无安处,强烈的“孤独感”油然而生。如何利用好网络的优势,完善当代大学生的网络生活,同时减轻他们的“孤独感”,使其身心健康发展是我们亟待解决的问题。  相似文献   
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