Mathematical models of canine right and left atria cardiomyocytes     

Ling Xia  Ying-lan Gong  Xiu-wei Zhu  Yu Zhang  Qi Sun  Heng-gui Zhang 《Journal of Zhejiang University. Science. B》2010,11(6):402-416

The aim of this study is to build two mathematical models of canine ionic currents specific to right atria and left atria.The canine left atria mathematical model was firstly modified from the Ramirez-Nattel-Courtemanche(RNC) model using the recently available experimental data of ionic currents and was further developed based on our own experimental data.A model of right atria was then built by considering the differences between right atria and left atria.The two developed models well reproduced the exper...  相似文献   

Neurochip based on light-addressable potentiometric sensor with wavelet transform de-noising     

Qing-jun Liu  Wei-wei Ye  Hui Yu  Ning Hu  Li-ping Du  Ping Wang 《Journal of Zhejiang University. Science. B》2010,11(5):323-331

Neurochip based on light-addressable potentiometric sensor(LAPS),whose sensing elements are excitable cells,can monitor electrophysiological properties of cultured neuron networks with cellular signals well analyzed.Here we report a kind of neurochip with rat pheochromocytoma(PC12) cells hybrid with LAPS and a method of de-noising signals based on wavelet transform.Cells were cultured on LAPS for several days to form networks,and we then used LAPS system to detect the extracellular potentials with signals d...  相似文献   

Congenital atresia of the left main coronary artery in an infant     

Su Ye Sohn  Gi Young Jang  Byung Min Choi 《Journal of Zhejiang University. Science. B》2010,11(7):539-541

Congenital atresia of the left main coronary artery is a rare occurrence, and surgical revascularizationbypass graft is required. We here report a rare case of congenital coronary anomaly in an infant. A 10-month-old male infant was admitted to the hospital with heart failure symptoms. Echocardiographic examinations revealed mitral valve regurgitation and ischemic changes of the anterolateral papillary muscle and chordae. Coronary angiography showed atresia of the left main coronary artery with a severe hypoplastic left anterior descending artery and a circumflex coronary artery. Unfortunately, sudden cardiac arrest occurred after catheterization and the infant did not recover despite of immediate cardiopulmonary resuscitation. Further studies are needed to find a newer diagnostic method to detect coronary anomaly in an infant, and coronary angiography, if necessary, has to be performed very carefully.  相似文献   

Electromagnetic effects on the biological tissue surrounding a transcutaneous transformer for an artificial anal sphincter system     

Zan P  Yang BH  Shao Y  Yan GZ  Liu H 《Journal of Zhejiang University. Science. B》2010,11(12):931-936

This paper reports on the electromagnetic effects on the biological tissue surrounding a transcutaneous transformer for an artificial anal sphincter. The coupling coils and human tissues, including the skin, fat, muscle, liver, and blood, were considered. Specific absorption rate (SAR) and current density were analyzed by a finite-length solenoid model. First, SAR and current density as a function of frequency (10–10⁷ Hz) for an emission current of 1.5 A were calculated under different tissue thickness. Then relations between SAR, current density, and five types of tissues under each frequency were deduced. As a result, both the SAR and current density were below the basic restrictions of the International Commission on Non-Ionizing Radiation Protection (ICNIRP). The results show that the analysis of these data is very important for developing the artificial anal sphincter system.  相似文献   

Carbon steel slag as cementitious material for self-consolidating concrete     

Yu-Chu Peng  Chao-Lung Hwang 《浙江大学学报(A卷英文版)》2010,11(7):488-494

This study deals with the recycling of carbon steel slag （CSS） to produce self-consolidating concrete （SCC）. Since the chemical composition of CSS is similar to that of Portland cement or blast furnace slag （BFS）, it is expected to behave similarly. In the current study, the pozzolanic activity index of CSS is examined. Furthermore, the use of CSS as a pozzolanic material to partially replace Portland cement in the production of SCC is tested. We designed concrete mixtures with different water-to- cementitious material ratios （w/cm） keeping water and superplasticizer （SP） contents constant. Results showed that the design and performance of all the concrete mixtures used in this investigation were comparable to those of SCC and high performance con- crete （HPC）. However, compared to ordinary plain concrete （OPC）, the additional CSS content increases the setting time. In the CSS mixtures set for 90 d, compressive strengths of 86%, 134% and 121% were attained as compared to the control concrete; the corresponding w/cm ratios were 0.28, 0.32 and 0.40, respectively. Verifying the soundness of the SCC for meeting the criteria for HPC, the ultrasonic pulse velocity （UPV） of CSS was found to be comparable to that of ordinary concrete. In conclusion, the recycling of CSS can be advantageously employed in the production of SCC.  相似文献   

Green’s functions for infinite planes and half-planes consisting of quasicrystal bi-materials     

Yang Gao 《浙江大学学报(A卷英文版)》2010,11(10):835-840

This paper deals with the combination of point phonon and phason forces applied in the interior of infinite planes and half-planes of 1D quasicrystal bi-materials. Based on the general solution of quasicrystals, a series of displacement functions are adopted to obtain Green＇s functions for infinite planes and bi-material planes composed of two half-planes in the closed form, when the two half-planes are supposed to be ideally bonded or to be in smooth contact. Since the physical quantities can be readily calculated without the need of performing any transform operations, Green＇s functions are very convenient to be used in the study of point defects and inhomogeneities in the quasicrystal materials.  相似文献   

Dynamics of a prestressed Timoshenko beam subject to arbitrary external load     

Ji-qing Jiang  Gui-ru Ye 《浙江大学学报(A卷英文版)》2010,11(11):898-907

The free vibration and transient wave in a prestressed Rayleigh-Timoshenko beam subject to arbitrary transverse forces are analyzed by the newly developed method of reverberation-ray matrix （MRRM）. The effects of shear deformation and rotational inertia are taken into consideration. With a Fourier transform technique, the general wave solutions with two sets of unknown amplitude coefficients are obtained in the transformed domain for an unbonded prestressed beam under the action of arbitrary external excitations. From the coupling at joints and the compatibility of displacements in each member, the free and forced vibration responses of a beam with various boundary conditions are finally evaluated through certain numerical algorithms, Results are presented for a simply-supported beam subject to either a point fixed load or moving load. Good agreement with the finite element method （FEM） is obtained. The present work is instructive for high-speed railway bridge design and structural health monitoring.  相似文献   

Tool wear criterion,tool life,and surface roughness during high-speed end milling Ti-6Al-4V alloy     

Song Zhang  Jian-feng Li 《浙江大学学报(A卷英文版)》2010,11(8):587-595

The objective of the present research is to investigate the relationship among tool wear, surface topography, and surface roughness when high-speed end milling Ti-6Al-4V alloy, and also to define an optimal flank wear criterion for the cutting tool to integrate tool life and the surface roughness requirements of the finish milling process. An annealed Ti-6Al-4V alloy was selected as the workpiece material, undergoing end milling with uncoated carbide inserts. The flank wear of the insert was observed and measured with the toolmaker＇s microscope. To examine machined surfaces, 3D surface topography was provided by the white light interferometer, and the arithmetical mean roughness （Ra） was calculated with the WYKO Vision32 software. The flank wear increases with cutting time, and the maximal flank wear is set as the flank wear criterion. As the cutting process progresses, tool wear is the predominant factor affecting the variation of surface roughness. According to the plots for the tool wear propagation and surface roughness variation, an optimal flank wear criterion can be defined which integrates the tool life and the surface roughness requirements for the finish milling process.  相似文献   

Numerical computations of the flow in a finite diverging channel     

Zhao-sheng Yu  Xue-ming Shao  Jian-zhong Lin 《浙江大学学报(A卷英文版)》2010,11(1):50-60

The flow in a finite diverging channel opening into a large space and resembling the experimental prototype of Putkaradze and Vorobieff （2006） was numerically investigated. The effects of the Reynolds number, initial condition, intersection angle, length of the wedge edges, and the outer boundary condition were examined. The numerical results showed that the flow in the wedge undergoes a change from symmetrical flow to unsymmetrical flow with a weak backflow, then a vortical （circulation） flow and finally an unsteady jet flow as the Reynolds number is increased for an intersection angle of 32° and a wedge edge of length 30 times the width of the inlet slit. For the unsteady flow, the jet attached to one side of the wedge constantly loses stability and rolls up into a mushroom-shaped vortex-pair near the outlet of the wedge. As the intersection angle is increased to 50°, a stable jet flow is observed as a new regime between the vortex and unsteady regimes. Both the intersection angle and the wedge length have negative effects on the stability of the flow, although the effect of the wedge length on the critical Reynolds number for the symmetry-breaking instability is not pronounced. The outer boundary condition was found not to affect the flow patterns inside the wedge significantly. At a certain Re regime above the onset of symmetry-breaking instability, the flows evolve into steady state very slowly except for the initial stage in the case of decreasing flow flux. Two different solutions can be observed within the normal observation time for the experiment, providing a possible explanation for the hysteresis phenomenon in the experiment.  相似文献   

Effect of a semi electro-mechanical engine valve on performance and emissions in a single cylinder spark ignited engine     

Bülent 《浙江大学学报(A卷英文版)》2010,11(2):106-114

In this study, an electro-mechanical valve （EMV） system for the intake valve ofa fottr stroke, single cylinder, overhead valve and spark ignition （SI） engine was designed and constructed. An engine with the EMV system and a standard engine were tested to observe the effects of the EMV on engine performance and emissions at different speeds under full load. The EMV engine showed improved engine power, engine torque and break specific fuel consumption （BSFC）. A 66% decrease in CO emissions was also obtained with the EMV system, but hydrocarbons （HC） and NOx emissions increased by 12% and 13% respectively.  相似文献