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IntroductionTo interpret test results correctly, understanding of the variations that affect test results is essential. The aim of this study is: 1) to evaluate the clinicians’ knowledge and opinion concerning biological variation (BV), and 2) to investigate if clinicians use BV in the interpretation of test results.Materials and methodsThis study uses a questionnaire comprising open-ended and close-ended questions. Questions were selected from the real-life numerical examples of interpretation of test results, the knowledge about main sources of variations in laboratories and the opinion of clinicians on BV. A total of 399 clinicians were interviewed, and the answers were evaluated using a scoring system ranked from A (clinician has the highest level of knowledge and the ability of using BV data) to D (clinician has no knowledge about variations in laboratory). The results were presented as number (N) and percentage (%).ResultsAltogether, 60.4% of clinicians have knowledge of pre-analytical and analytical variations; but only 3.5% of them have knowledge related to BV. The number of clinicians using BV data or reference change value (RCV) to interpret measurements results was zero, while 79.4% of clinicians accepted that the difference between two measurements results located within the reference interval may be significant.ConclusionsClinicians do not use BV data or tools derived from BV such as RCV to interpret test results. It is recommended that BV should be included in the medical school curriculum, and clinicians should be encouraged to use BV data for safe and valid interpretation of test results.  相似文献   
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Physical activity (PA) is important in ensuring a healthy population. It is dependent on various socio-demographic (SD) factors, such as age, gender, employment and marital status. A limited number of studies have investigated the relationship between SD factors and PA but research exploring this relationship from the perspective of gated and non-gated neighbourhoods is scarcer. Therefore, the objective of this study is to investigate the relationship between SD factors and PA variables in gated and nongated neighbourhoods in Karachi Pakistan. Results of the independent sample t-test and Pearson chi-square showed that young and single people do more sports activities in gated neighbourhoods. Women, unemployed people and public transport users walk more in non-gated neighbourhoods. In conclusion, future neighbourhoods should have more pedestrian friendly areas and a larger number of PA facilities, rather than building more walls and gates.  相似文献   
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Assessment is a critical component of educational practices and thus impacts educational reform efforts. This article reviews and considers assessment from 2 perspectives: a focus on accountability and a focus on continuous improvement. A class of preservice and practicing science teachers explored notions of assessment while experiencing peer assessment as part of the class. Their online conversations about the processes of establishing quality criteria for peer assessment and their reflections on the experiences compose the primary data source. Two purposes for assessment, accountability and continuous improvement, arose from the data and created conflicts within the individuals and the class. To resolve this conflict, we propose a framework for viewing assessment as part of an integral model (Wilber, 2004 Wilber, K. 2004. Kosmic consciousness [CD], Boulder, CO: Sounds True..  [Google Scholar]) that includes and transcends the dualities.  相似文献   
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This article aims to provide an overall picture of the use of Twitter as a significant social media tool by mayors in Turkey and to investigate, using content analysis and tweet categorization, whether Twitter is used by mayors in Turkey to offer better public services. Thus, this study focuses on the impact of Twitter in Turkey on transparent, participatory and citizen-oriented local public services. Our analysis has revealed that mayors in Turkey use Twitter especially to share information, send personal messages and share their location and activities. The use of Twitter for transparent, participatory and citizen-oriented public service delivery is not common among mayors. Twitter is adopted and used by mayors mostly for the purposes of self-promotion and political marketing in Turkey.  相似文献   
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Introduction:

Optimal storage of serum specimens in central laboratories for a long period for multicenter reference interval studies, or epidemiologic studies remains to be determined. We aimed to examine the analytical stability of chemistry analytes following numerous freeze-thaw and long term storage.

Materials and methods:

Serum samples were obtained from 15 patients. Following baseline measurement, sera of each subject were aliquoted and stored at −20 °C for two experiments. A group of sera were kept frozen for up to 1, 2 and 3 months and then analyzed for stability. The other experiment consisted of one to ten times of freeze and thaw cycles. Total of 17 chemistry analytes were assayed at each time point. The results were compared with those obtained from the initial analysis of fresh samples. Median or mean changes from baseline (T0) concentrations were evaluated both statistically and clinically according to the desirable bias.

Results:

Of the analytes studied, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase (CK), gamma-glutamyl transferase (GGT), direct bilirubin, glucose, creatinine, cholesterol, triglycerides, high density lipoprotein (HDL) were stable in all conditions. Blood urea nitrogen (BUN), uric acid, total protein, albumin, total bilirubin, calcium, lactate dehydrogenase (LD) were changed significantly (P < 0.005).

Conclusions:

As a result, common clinical chemistry analytes, with considering the variability of unstable analytes, showed adequote stability after 3 months of storage in sera at −20 °C, or up to ten times of freeze-thaw cycle. All the same, such analysis can only be performed for exceptional cases, and this should be taken into account while planning studies.  相似文献   
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目的:本研究旨在测定Scandix pecten-veneris L.的植物素和评价其生物学潜力。方法:测定S.pecten-veneris提取物中植物素的含量,包括生物碱、黄酮、多酚和单宁。使用2,2-二苯基-1-苦肼基(DPPH)测定抗氧化活性;同时通过铁还原/抗氧化能力(FRAP)测定还原能力;使用琼脂扩散测定法评价对七种细菌和四种真菌菌株的抗微生物活性。同时,对脲酶、磷酸二酯酶-Ⅰ和过氧化氢酶-Ⅱ进行酶抑制研究。结论:沙门氏菌显示出适度的抗自由基活性;羟基自由基的潜能降至初始值的20%左右。S.pectenveneris多种提取物的抗氧化活性与总酚含量呈线性相关。S.pecten-veneris叶对金黄色葡萄球菌表现出最高的抑制活性;对白色念珠菌表现出到最高的抗真菌活性。植物提取物对脲酶的活性最有效;对磷酸二酯酶-Ⅰ和碳酸酐酶-Ⅱ显示出中等活性。结果表明,S.pecten-veneris具有良好的药用潜力,可用于治疗一些特定的疾病。  相似文献   
119.
The purpose of this study was to examine factors predictive of college students' academic stress. Three hundred seven undergraduate students (179 men, 128 women) participated in the study. Results indicated that female college students had higher academic stress than did male college students. Bivariate correlations and multiple regression analyses revealed that life satisfaction, locus of control, and gender were significant predictors of academic stress. Directions for future research and implications for counselors are discussed.  相似文献   
120.
ABSTRACT

The purpose of this study is to investigate the relationships between organizational culture and academic performance among higher education institutions. The sample was composed of 647 faculty members working in the colleges of education, health, engineering, law, economics, and administrative sciences in four central research universities in Turkey. The Organizational Culture Assessment Instrument (OCAI) was used to describe organizational culture, whereas University Ranking by Academic Performance (URAP) data were used to investigate academic performance. A multilevel analysis in which one unit of analysis (i.e., faculty member) was nested within another (i.e., college) was performed. The original contribution made to the literature by this research is its examination of the relationships between organizational culture and tangible performance indicators (e.g., the number of academic publications and citations). Results show that three different culture types were observed in the universities: Innovative team culture, competitive culture, and hierarchic culture. Although significant relationships were found between academic performance and both competitive culture and innovative team culture, the sole significant predictor of academic performance was competitive culture. One particularly interesting finding was that whereas competitive culture was effective on quantitative indicators (i.e., number of publications and number of citations), only innovative team culture affected the indicators related to effectiveness (i.e., article impact level and citation impact level).  相似文献   
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