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51.
Vaccines require optimal adjuvants including immunopotentiator and delivery systems to offer long term protection from infectious diseases in animals and man. Initially it was believed that adjuvants are responsible for promoting strong and sustainable antibody responses. Now it has been shown that adjuvants influence the isotype and avidity of antibody and also affect the properties of cell-mediated immunity. Mostly oil emulsions, lipopolysaccharides, polymers, saponins, liposomes, cytokines,ISCOMs (immunostimulating complexes), Freund's complete adjuvant, Freund's incomplete adjuvant, alums, bacterial toxins etc.,are common adjuvants under investigation. Saponin based adjuvants have the ability to stimulate the cell mediated immune system as well as to enhance antibody production and have the advantage that only a low dose is needed for adjuvant activity. In the present study the importance of adjuvants, their role and the effect of saponin in immune system is reviewed.  相似文献   
52.
OBJECTIVE: To conceptualize the underlying causes of the medical neglect of children in a developing country and to provide suggestions for the management of neglect by pediatricians. METHODS: A case history of a 4-year-old boy from Turkey with neglect of the required treatment for acute lymphoblastic leukemia is used to examine the causes and management of medical neglect. Results: Although epidemiological studies on child neglect are lacking, this case exemplifies how in DEVELOPING countries, reasons for neglect or non-compliance with medical recommendations and the roles and actions taken by the health care and the social service systems may differ from western populations. Common to both western and developing countries, the characteristics of the child, family, and society may be reasons for medical neglect. However, cultural fatalistic beliefs profoundly present in the developing world may also contribute to the medical neglect of a child. Identification of the neglect, a comprehensive, multidisciplinary assessment emphasizing the strengths within the family and the society, and the determination of the pediatric team to act in the best interest of the child may result in resolution of the neglect even in circumstances where resources within systems are not sufficient. CONCLUSIONS: In developing countries, increased emphasis on child neglect, its prompt recognition and management within the pediatric profession as well as at a health care and social service system levels are needed to address this prevalent and potentially fatal child health problem.  相似文献   
53.
This article examines how climate change is represented by the mainstream press in a developing country context characterized by long-term avoidance of the issue. Study 1 establishes the issue coverage trends in two mainstream Turkish newspapers (1997–2013). Study 2 focuses on the news sections of these papers that were used for reporting about the issue in the first attention cycle (1997–2009) to summarize the knowledge and meaning dimensions presented to the Turkish public sphere. The findings show that the issue became part of the press agenda only after the mid-2000s, with a peak in 2007 (Study 1), and that climate change is represented as anthropogenic and alarming/uncontroversial, by drawing on dramatic consequences. These are constructed simultaneously as already “out there” in the country, and as to be dealt with globally, that is, from outside (Study 2). We discuss the findings by linking them to findings from other developing countries.  相似文献   
54.
The study examined the role of action research in promoting critical reflective thinking among twenty preservice teachers engaged in a year-long middle level program. Data from collaborative discussions, final written documents, presentations, and follow-up surveys revealed that conducting action research (a) engaged them in inquiry into their own practice, (b) was a means to reflect upon and determine ways to change their teaching practices, and (c) promoted critical reflection in a collaborative learning environment. Results underscore the importance of preservice teachers critically reflecting to gain insights into teaching and student learning as they are engaged in action research.  相似文献   
55.
The purpose of this nationwide survey was to assess young Turkish pupils’ environmental literacy (EL) level by considering six EL components. The sample of the study comprised of 2,412 fifth graders selected from 78 elementary schools (26 private and 52 public) in 26 provinces of Turkey. Data were obtained through the use of an elementary school environmental literacy instrument (ESELI) including five parts and total of 75 items. The results revealed that the composite EL score of the students was found to be 149.66 (SD = 26.19), suggesting a moderate level of EL among 61% percent of the students (n = 1,545). On the other hand, more than a quarter of the participants (27.3%, n = 659) held high level EL, whereas only 22 students (0.9%) showed low level EL. The implications of the results to policy, practice, and further research were discussed at the end of the study.  相似文献   
56.
The aim of this article is to analyse the latest implementations and issues raised in Turkish non‐formal education from a historical perspective in Turkey. The high population rate and lack of adequate educational opportunities for adults and migration from rural areas to urban areas caused many educational, social and cultural problems in non‐formal education. For solving all the problems, Turkey followed the latest developments in the world about the aims and functions of non‐formal adult education and organised several different adult education programs in terms of integration to international bodies such as European Union and so forth. These programs aim to reach a wide range of people from rural and urban settings, the employees, employers, farmers, students, tradesmen, housewives, artisans and many others. The most important educational characteristic of this audience is that they are not regular students. The organisation way of non‐formal education differ from other developed countries in essence. In social terms, the non‐formal education for adults does not only provide professional and technical training; but also provides the learners with basic literacy and helps continue their educational life, contributes to preservation and improvement of national and cultural values, creates an awareness of citizenship and democratic thinking in Turkey.  相似文献   
57.
This study aims to clarify the effect of emotional intelligence (EI) on negative feelings (stress, anxiety, burnout and depression) in a gender specific model. Four hundred and twenty-five primary school teachers (326 males, 99 females) completed the measures of EI, stress, anxiety, burnout and depression. The multi-group analysis was performed using a structural equation approach. The moderated mediation results show that there are gender related differences in the relationships of age, emotional intelligence, stress, anxiety, burnout and depression. The results imply that school managers should take into consideration the teachers’ personal variables such as gender and age in order to assess the use of emotional intelligence in coping with negative feelings at the place of work effectively.  相似文献   
58.
The Internet has become one of the most common instructional tools because of recent developments in telecommunications and Internet technology. Accordingly, educators increasingly support the use of the Internet in the social studies classroom. Thus, the purpose of this study was to investigate pre‐service elementary teachers’ beliefs about the use of the Internet in the social studies classroom. Data were collected through an open‐ended questionnaire from 37 pre‐service elementary teachers in a large Turkish university. An inductive analysis approach was used to analyse the data. Thus, the emergent patterns of the data were used to develop coding categories. The data analysis indicated that the majority of the participants supported the use of the Internet in the social studies classroom, while they acknowledged the disadvantages and negative aspects of the use of the Internet.  相似文献   
59.
User interfaces that utilise human gestures as input are becoming increasingly prevalent in diverse computing applications. However, few designers possess the deep insight, awareness and experience regarding the nature and usage of gestures in user interfaces to the extent that they are able to exploit the technological affordances and innovate over them. We argue that design students, who will be expected to envision and create such interactions in the future, are constrained as such by their habits that pertain to conventional user interfaces. Design students should gain an understanding of the nature of human gestures and how to use them to add value to UI designs. To this end, we formulated an ‘awareness course’ for design students based on concepts derived from mime art and creative drama. We developed the course iteratively through the involvement of three groups of students. The final version of the course was evaluated by incorporating the perspectives of design educators, an industry expert and the students. We present the details of the course, describe the development process, and discuss the insights revealed by the evaluations.  相似文献   
60.
Psoriasis patients are determined to have a high ratio of coronary artery calcification. Fetuin-A and osteoprotegerin are systemic calcification inhibitors and related to vascular calcification and cardiovascular mortality. In this study we investigated the relationship between fetuin-A and osteoprotegerin levels in psoriasis patients. The study included 40 healthy volunteers and 40 psoriasis patients. Venous blood were collected from healthy volunteers and psoriasis patients in order to search the fetuin-A and osteoprotegerin levels. Disease severity were grouped as mild, moderate and severe according to psoriasis area and severity index (PASI). The relationship between fetuin-A and osteoprotegerin levels and clinical features as sex, PASI and presence of psoriatic arthritis were analyzed. Fetuin-A levels in psoriasis patients were statistically lower than the control group (p < 0.001). In serum osteoprotegerin levels, no statistically significant difference was found in two groups (p > 0.05). Serum fetuin-A and osteoprotegerin level differences were not statistically significant between patients with psoriatic arthritis history and those without. When we grouped patients in respect of their sexes fetuin-A and osteoprotegerin levels of males and females were not significantly different (p > 0.05). No correlation was detected between the ages and PASI scores and the fetuin-A and osteoprotegerin levels of patients. As a result fetuin-A levels in psoriasis patients are found to be low but not related to disease severity. In the light of our results we concluded that fetuin-A may have a role in psoriasis pathogenesis and may contribute to the calcification process developed in psoriasis.  相似文献   
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