The angiogenetic effect of intramuscular administration of b-FGF and a-FGF on cardiac muscle: the influence of exercise on muscle angiogenesis     

Efthimiadou A  Asimakopoulos B  Nikolettos N  Giatromanolaki A  Sivridis E  Lialiaris TS  Papachristou DN  Kontoleon E 《Journal of sports sciences》2006,24(8):849-854

Although angiogenetic therapy using recombinant growth factors holds much hope for the treatment of ischaemic diseases, there are still many unanswered questions, including the method of administration, the correct dose of these factors, and the duration of the therapeutic approach. Exercise has also been suggested to induce neovascularizaiton in muscles. We evaluated the angiogenetic effects of the intramuscular administration of basic-fibroblast growth factor (b-FGF) and acidic-fibroblast growth factor (a-FGF) in rat heart, compared with rats who exercised daily. In conclusion, both the intramuscular administration of b-FGF and exercise increased significantly angiogenesis in the heart in contrast to the intramuscular administration of a-FGF, which was ineffective.  相似文献   

Meta-analysis: a tool for medical and scientific discoveries.     

C L Schell  R J Rathe 《Bulletin of the Medical Library Association》1992,80(3):219-222

Medicine has made increasing use of meta-analysis, largely as a quantitative procedure for combining results of clinical trials. Meta-analysis begins with a comprehensive review of the literature. The next step is a systematic analysis of the quality and content of each study. Finally, results are combined statistically and conclusions are drawn from this new overview of the data. This paper presents a brief historical perspective on the use of meta-analysis in medicine with emphasis on the medical library. The authors conclude that in the future, medical librarians will play a significant role in the application of this useful technique.  相似文献   

Chaos theory, informational needs, and natural disasters   总被引：2，自引：0，他引：2  

Timothy L. Sellnow  Matthew W. Seeger  Robert R. Ulmer 《Journal of Applied Communication Research》2002,30(4):269-292

This study applies chaos theory to a system-wide analysis of crisis communication in a natural disaster. Specifically, we analyze crisis communication during the 1997 Red River Valley flood in Minnesota and North Dakota. This flood, among the worst in modern American history, consumed entire metropolitan areas, displacing thousands of people. The conditions and decisions leading to the disaster, and the subsequent reactions are retraced. Communication related to river crest predictions (fractals), the shock at the magnitude of the crisis (cosmology episode), novel forms of reorganizing (self-organization), and agencies that aided in establishing a renewed order (strange attractors) are evaluated. Ultimately, we argue that preexisting sensemaking structures favoring rationalized, traditional views of a complex system led officials to make inappropriately unequivocal predictions and ultimately diminished the effectiveness of the region's crisis communication and planning.  相似文献   

The reliability of distance run tests for children in grades K-4.     

R E Rikli  C Petray  T A Baumgartner 《Research quarterly for exercise and sport》1992,63(3):270-276

The purpose of this study was to determine test-retest reliability for the 1-mile, 3/4-mile, and 1/2-mile distance run/alk tests for children in Grades K-4. Fifty-one intact physical education classes were randomly assigned to one of the three distance run conditions. A total of 1,229 (621 boys, 608 girls) completed the test-retests in the fall (October), with 1,050 of these students (543 boys, 507 girls) repeating the tests in the spring (May). Results indicated that the 1-mile run/walk distance, as recommended for young children in most national test batteries, has acceptable intraclass reliability (.83 less than R less than .90) for both boys and girls in Grades 3 and 4, has minimal (fall) to acceptable (spring) reliability for Grade 2 students (.70 less than R less than .83), but is not reliable for children in Grades K and 1 (.34 less than R less than .56). The 1/2 mile was the only distance meeting minimal reliability standards for boys and girls in Grades K and 1 (.73 less than R less than .82). Results also indicated that reliability estimates remained fairly stable across gender and age groups from the fall to spring testing periods, with the exception of the noticeably improved values for Grade 2 students on the 1-mile run/walk test. Criterion-referenced reliability (P, percent agreement) was also estimated relative to Physical Best and Fitnessgram run/walk standards. Reliability coefficients for all age group standards were acceptable to high (.70 less than P less than .95), except for Fitnessgram standards for 5-year-old girls on the 1-mile test for both fall and spring and for 6-year-old boys and girls on the 1-mile test administered in the spring.  相似文献   

For sale, by degrees: Overseas students and the commodification of higher education in Australia and the United Kingdom     

Anthony R. Welch 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》1988,34(3):387-395

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Diagnosing dyslexia: IQ regression plus cut-points.     

R A Dykman  P T Ackerman 《Journal of learning disabilities》1992,25(9):574-576

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Book reviews     

Louise L. Stevenson  Albert N. Greco  Ann Okerson  Beth Luey 《Publishing Research Quarterly》1991,7(1):85-91

Association of Research Libraries  相似文献   

Marketing the hospital library to physicians: one approach     

E R Cooper 《Bulletin of the Medical Library Association》1991,79(1):86-87

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Teacher perceptions of temperament characteristics of children classified as learning disabled     

C D Cardell  R S Parmar 《Journal of learning disabilities》1988,21(8):497-502

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Morphological proportionality in elite age group North American divers.     

D Sovak  M R Hawes  K Plant 《Journal of sports sciences》1992,10(5):451-465

The purpose of this investigation was to describe the morphological parameters that characterize elite age group divers. Comparisons are made to normative age group data from the Coquitlam Growth Study and the constancy of important characteristics from age group to age group is examined. Data were collected on 27 male and 28 female elite divers who participated in the 1990 North American Age Group Diving Championships. Body build, body composition and skinfold corrected diameters were determined from 36 anthropometric parameters and analysed by ANOVA, t-test and Phantom z-scores procedures. All age groups except the 14- to 15-year-old males were significantly (P < or = 0.05) shorter than their norms but recorded higher androgyny index values. The estimated relative muscle mass increased significantly (P < or = 0.05) with age for males at all ages (40.8-46.3%). The 16- to 18-year-old females had a significantly (P < or = 0.05) larger relative muscle component compared to the younger age groups (40.1-38.4%). When normalized for height, active tissue development of the extremities was comparable between the sexes except in the forearm. The results indicate that at all age levels short stature is an important characteristic for divers. Analysis of regional active tissue development provides further insight into sport-specific prerequisites for success at elite levels.  相似文献