The Superintendent in His Lair     

Nora Collins 《Clearing house (Menasha, Wis.)》2013,86(2):105-106

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Assembly Programs Integrated with the Instructional Activities of the School     

Nora E. Dodson 《Clearing house (Menasha, Wis.)》2013,86(2):109-113

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Efficient capture of circulating tumor cells with a novel immunocytochemical microfluidic device     

Nora Dickson M  Tsinberg P  Tang Z  Bischoff FZ  Wilson T  Leonard EF 《Biomicrofluidics》2011,5(3):34119-3411915

Ability to perform cytogenetic interrogations on circulating tumor cells (CTCs) from the blood of cancer patients is vital for progressing toward targeted, individualized treatments. CTCs are rare compared to normal (bystander) blood cells, found in ratios as low as 1:10⁹. The most successful isolation techniques have been immunocytochemical technologies that label CTCs for separation based on unique surface antigens that distinguish them from normal bystander cells. The method discussed here utilizes biotin-tagged antibodies that bind selectively to CTCs. The antibodies are introduced into a suspension of blood cells intending that only CTCs will display surface biotin molecules. Next, the cell suspension is passed through a microfluidic channel that contains about 9000 transverse, streptavidin coated posts. A CTC making contact with a post has the opportunity to engage in a biotin-streptavidin reaction that immobilizes the cell. Bystander blood cells remain in suspension and pass through the channel. The goal of the present study is to establish the technical performance of these channels as a function of antigen density and operating conditions, especially flow rate. At 18 μL/min, over 70% of cells are captured at antigen densities greater than 30 000 sites/cell while 50% of cells are captured at antigen densities greater than 10 000. It is found that lower flow rates lead to decreasing cell capture probabilities, indicating that some streamlines develop which are never close enough to a post to allow cell-post contact. Future modeling and streamline studies using computational fluid dynamics software could aid in optimization of channel performance for capture of rare cells.  相似文献   

News Selection Within Customer Magazines     

Nora Denner  Thomas Koch  Sascha Himmelreich 《Journalism Practice》2018,12(7):888-900

Customer magazines blur the boundaries between journalistic reporting and organizational information. On the one hand, customer magazines are intended to communicate the interests, brands, products, and services of an organization. On the other hand, their topics, style, and layout resemble those of journalistic publications, from which readers expect independent and objective reporting. While customer magazines are distributed in high numbers throughout different industries and play an increasingly important role in the media landscape, they have hardly been the focus of researchers to date. It is therefore quite unclear how editorial decisions are made within these publications. This study investigated the relevance of journalistic news factors for topic selection in customer magazines and the extent to which these factors differ from those of journalistic publications. We conducted a quantitative survey of customer magazines’ editors-in-chief in Germany (N?=?143). We compared their responses on the relevance of news factors to the findings of a survey of senior journalists. The findings revealed clear differences in the use of news factors between the two groups.  相似文献   

Psychological Benefits of Participation in Three-dimensional Virtual Worlds for Individuals with Real-world Disabilities     

Richard L. Gilbert  Nora A. Murphy  Alice B. Krueger  Ann R. Ludwig  Torri Y. Efron 《International Journal of Disability, Development & Education》2013,60(3):208-224

One hundred and ninety-six individuals with real-world disabilities were administered a battery of psychological adjustment measures soon after joining the three-dimensional virtual world of Second Life^®. After three months, 61 participants who continued to be actively involved in Second Life were re-administered the adjustment measures and completed a survey about their virtual and real-life experiences during the interval between assessments. Participants’ scores significantly improved on measures of affective states (depression, anxiety, positive emotion, life satisfaction, and feelings of loneliness) and self-evaluation (self-esteem). An index of overall change was associated with the number of virtual friends and group affiliations in Second Life, as well as feelings about the self as a result of involvement in the virtual world. The current study provides initial empirical support that three-dimensional virtual worlds can serve as a psychologically beneficial context for individuals with real-life disabilities.  相似文献   

Creating New Identities in Design Education     

Hannah Rose Mendoza  Claudia Bernasconi  Nora M. MacDonald 《The International Journal of Art & Design Education》2007,26(3):308-313

An international education opportunity has been created for design students at West Virginia University. This experience is unique because it takes an interdisciplinary approach to design that exposes students to the idea of a larger design methodology common to design professions. Students take core courses with students from a variety of design fields, including interior design, fashion design, fashion merchandising, landscape architecture, art, and graphic design. Through this interaction, students gain an understanding of the interrelationships among design fields, learn to appreciate new perspectives, and begin to appreciate the place of their field as part of the design community as a whole.  相似文献   

School Leaving: A Longitudinal Perspective Including Neighborhood Effects   总被引：6，自引：0，他引：6  

Margaret E. Ensminger  Rebecca P. Lamkin  Nora Jacobson 《Child development》1996,67(5):2400-2416

Using 1970 and 1980 census data from 202 tracts in the Chicago metropolitan region, we examine whether neighborhoods influence the likelihood of high school graduation for a cohort of African-American children followed from 1966 to 1993. Neighborhood-level variables included percent living below poverty and percent in white-collar occupations. We test for the possible direct, indirect, and interactive effects of these neighborhood indicators on the likelihood of school dropout. Our examination found the advantage of living in a neighborhood characterized by a high percentage of residents who work in white-collar occupations. Male adolescents who lived in a middle-class neighborhood were more likely to graduate from high school, even with family background, early school performance, adolescent family supervision, and adolescent marijuana use controlled. These findings are consistent with findings from three other studies. However, living in a poverty census tract did not seem to influence the likelihood of high school graduation or school leaving over and above the impact of family and individual characteristics. There also were no neighborhood effects for females.  相似文献   

Expanding Dispositions for Literacy: General Educators as Literacy Gatekeepers     

Lesley Nora Siegel  Kristina Marie Valtierra 《Clearing house (Menasha, Wis.)》2017,90(3):93-97

Students with disabilities continue to be denied literacy rich experiences with their non-disabled peers. Throughout this article the authors explore how narrow, ability-focused teacher dispositions can perpetuate low expectations and can preemptively deny students with disabilities access to meaningful literacy experiences. Hence, the development of an inclusive literacy disposition is crucial to providing access to robust learning experiences for students with disabilities. The authors describe a research study that utilizes journal writing and a role-play intervention with pre-service general educators in a graduate literacy methods course. Analysis of post-intervention data suggests it is possible to shift narrow, ability-orientated dispositions to broader and more inclusive conceptualizations that support students with disabilities. Implications for both research and practice are discussed.  相似文献   

Fifth graders metacognitive knowledge: general or domain-specific?     

Nora Neuenhaus  Cordula Artelt  Klaus Lingel  Wolfgang Schneider 《European Journal of Psychology of Education - EJPE》2011,26(2):163-178

The purpose of the present study was to investigate the structure of metacognitive knowledge in fifth grade pupils and its relation to school achievement. Since the structure of metacognitive knowledge is controversially discussed with little empirical evidence for either its domain specificity or its domain transferability, the debate remains somewhat hypothetical up to date. In theory it is assumed that the development of metacognitive knowledge begins highly domain and situation-specific and becomes more flexible and domain-transcending with practice and experience (Borkowski et al. 2000). As standardized measures to assess metacognitive knowledge of students in the age group under investigation were missing, newly developed instruments were applied to assess the domain-specific metacognitive knowledge in reading and mathematics as well as domain-transcending metacognitive knowledge. The influences of domain-specific and general metacognitive knowledge on school achievement in the two domains were analyzed. While findings on the structure of metacognitive knowledge indicate some degree of domain specificity, they also point out a strong relation between general metacognitive knowledge and domain-specific metacognitive knowledge. The cross-sectional relation between metacognitive knowledge and academic achievement were relatively low. Implications for future research will be discussed.  相似文献   

Classroom dimensions predict early peer interaction when children are diverse in ethnicity, race, and home language   总被引：1，自引：0，他引：1  

Carollee Howes  Alison Wishard GuerraAllison Fuligni  Eleanor ZuckerLinda Lee  Nora B. ObregonAsha Spivak 《Early childhood research quarterly》2011,26(4):399

The purpose of this study was to test a model for predicting preschool-age children's behaviors with peers from dimensions of the classroom and teacher-child relationship quality when the children were from diverse race, ethnic, and home language backgrounds. Eight hundred children, (M = age 63 months, SD = 8.1 months), part of the National Evaluation of Early Head Start, participated in this study just prior to entering kindergarten. We observed children with peers in their classrooms and rated classroom peer group size, affective climate for peer interaction, teacher management of the classroom, and materials for dramatic play. Teachers reported on teacher-child relationship quality. Children from Spanish-speaking homes played similarly in classrooms where Spanish was and was not spoken. After control variables and receptive vocabulary scores were entered into the model, classroom dimensions and teacher-child relationship quality significantly predicted pretend play, anxious-withdrawn, aggressive, and victim of peer aggression behaviors with peers. Children engaged in more pretend play and received lower ratings of being the victim of peer aggression when classroom groups were smaller. When teachers perceived teacher-child relationships as lower in conflict and higher in closeness, children's anxious-withdrawn, aggressive, and victim of aggression ratings were lower. Children's ratings of being the victim of peer aggression were higher when ratings of classroom positive peer climate were lower. Child-teacher ethnic or racial match did not moderate these predictions.  相似文献