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41.
42.
Jason L. Anthony Jeffrey M. Williams Rachel G. Aghara Martha Dunkelberger Barbara Novak Anuja Divatia Mukherjee 《Reading and writing》2010,23(8):969-994
Individual differences in abilities to form, access, and hone phonological representations of words are implicated in the development of oral and written language. This study addressed two important gaps in the literature concerning measurement of individual differences in phonological representation. First, we empirically examined the dimensionality of phonological representation abilities. Second, we empirically compared how well typical measures index various representation-related phonological processing abilities. Specifically, nine measures of accessibility to and distinctness of phonological presentations were administered to 175 3-, 4-, and 5-year-old children. Confirmatory factor analysis validated three separate but correlated phonological processing abilities, i.e., efficiency of accessing phonological codes, precision of phonological codes as reflected in speech production, and precision of phonological codes as reflected in speech perception. The named phonological processing abilities were equally good measures of a second-order phonological representation factor. While most prototypic measures were excellent indicators of first-order phonological abilities, they were only modest indicators of phonological representation. 相似文献
43.
The phrases ‘transient growth’ and ‘non-normality’ have become common parlance in fluid mechanics nowadays. We present these
ideas with a simple two-dimensional system, to enable the reader to look for transient growth, as a trigger for nonlinear
behaviour to set in, in a variety of situations probably having nothing to do with fluid mechanics. The article is aimed at
undergraduate students of science, engineering, finance, etc., and the material is based completely on the excellent books
of Trefethen and Embree, and Schmid and Henningson [1,2]. 相似文献
44.
Mobile payment technology continues to spread across the globe, but its diffusion has not been uniform. Its low usage in developing economies is of particular concern to policymakers since this technology has the potential to enable financial inclusion. In this study, in order to develop policy interventions for greater usage, we comparatively analyze factors impacting actual usage and future use intention. India, with its uneven trajectory of mobile payments, gives us an appropriate field to investigate citizens’ usage behaviour. Considering users’ perceptions of both positive and negative attributes of the technology, we develop research models under the umbrella of the valence framework. We utilize technology affordances and constraints theory (TACT) to refine the research models through an understanding of various innovative uses. To test the valence-TACT models, we collect survey responses of 551 citizens across four Indian cities. The results from the models show how certain factors, such as convenience, reflection, and security, have different impacts on actual usage and future use intention, respectively. These findings have implications for critical issues like security, risk, and digital literacy, and can help in the design of policy recommendations for enhancing the use of mobile payments, thereby impacting financial inclusion for all. The valence-TACT model provides a theoretical contribution to mobile payment and innovation literature and also offers several policy insights. 相似文献
45.
Rahul Siddharthan 《Resonance》1999,4(5):61-70
In the earlier part of this article, an introduction to musical scales, counterpoint and harmony was given. In this part these
themes are developed further with reference to Bach’s music and the emergence of the equally tempered scale. 相似文献
46.
Rani James G. Ramesh Lakshmi Krishnamoorthy Rahul Bhagat Shilpa Chadaga Vijayalaxmi Deshmane Girija Ramaswamy 《Indian journal of clinical biochemistry : IJCB》2014,29(1):21-28
Vascular endothelial growth factor (VEGF) plays an important role in the development of Breast Cancer. The aim of this study was to investigate the association of polymorphisms in the VEGF gene on prognosis of Breast Cancer patients. This study comprised 200 patients with histologically confirmed cases of Breast cancer and 200 controls. Genotyping of the VEGF gene polymorphisms at +405G>C,−1154G>A, were performed by PCR-RFLP analysis. Preoperative plasma VEGF levels were determined by ELISA. Amongst both cases and controls, the genotypic distribution of the individual SNPs were all in Hardy–Weinberg equilibrium. Mean VEGF level was significantly elevated in cases compared to controls (t = 8.248; P < 0.001). No significant association was found between +405G>C,−1154G>A VEGF polymorphism and Breast Cancer. Logistic regression analysis revealed that 405GG & 1154GG were associated with higher levels of VEGF. 相似文献
47.
Technological progress in an industry is enabled by the collective R&D efforts of suppliers, users and research organizations. In this study, we explore how the pattern of R&D collaboration within the industry community evolves over the technology life cycle. We propose that as the technology evolves from an initial emergence stage to subsequent stages of growth and maturity, there is a corresponding change in the opportunities and challenges confronting industry participants. This results in a shift not only in the relative propensities for internal and collaborative R&D, but also in the distribution of the different types of collaborative interactions involving research organizations, suppliers and users. The context for the study is the global semiconductor manufacturing industry from 1990 to 2010. During this period, the industry experienced exponential technological progress that was fueled by the deep ultraviolet (DUV) manufacturing technology. We draw upon a comprehensive archival dataset of more than 12,000 articles presented in industry technical conferences to analyze the pattern of collaborative R&D during the emergence, growth and maturity stages of the DUV technology. The observed trends in the semiconductor manufacturing industry point to intriguing shifts in the efforts and interactions among suppliers, users and research organizations as they collectively push the technology envelope forward. 相似文献
48.
49.
Mukherjee Manjari Rajashree A. Mokal Anagha A. Malur Chandra S Choksi Meena P. Desai 《Indian journal of clinical biochemistry : IJCB》1992,7(1):41-43
Urinary iodine was estimated chemically by the kinetic method, after mineralisation of the organic iodide by alkaline ashing. The experimental conditions were optimised. The methodological modifications of an existing technique are highlighted. Urinary iodine levels were determined in 349 school children of Bombay, of whom 163 had Grade IA/IB/II goitre and the remaining 186 did not have goitre. Urinary iodine concentration (Mean±SEM) of the control (n=186) and the goitre (n=163) groups were 76.47±4.97 and 71.09±6.23 μg/g creatinine respectively. The difference in the means was statistically not significant. Urinary iodine exhibited a log-normal distribution. It is concluded that the presence of goitre in the clinically euthyroid group of children was not caused by iodine deficiency. 相似文献
50.
V. Thakur A. K. Anand U. Mukherjee D. Ghosh 《Indian journal of clinical biochemistry : IJCB》2003,18(2):27-33
Appropriate therapeutic measures can improve the life expectancy of patients with ovarian malignancy. There has been a pressing
need for serodiagnostic assays to enable, the close patient monitoring. Cancer Antigen 125 (CA125) has been described as a
useful marker in patient monitoring for ovarian malignancy. Keeping this in view, the present study was planned. 40 consecutive
female patients of ovarian carcinoma (mean age 52.4±10.7 years) were selected for serum CA125 analysis during the period of
year 1995–2001. The tumour marker concentration was compared with histologic types of ovarian tumour and the FIGO staging
of the disease. 25 healthy females (mean age 35.2–10.4 years) served as control. Mean serum CA125 concentrations in patients
with papillary serous adenocarcinoma(Mean±%CV 1571±121.5 U/ml) was much higher than patients with mucinous adenocarcinoma(775±78U/ml).
Mean serum CA125 concentration in endometrioid carcinoma was very high(2853±136 U/ml). The patient with clear cell carcinoma
however had shown moderate increase(60 U/ml). No correlation was found between serum CA125 concentration and the FIGO staging
of disease.
Quantitation of CA125 was most helpful in monitoring the response of treatment and followup of the patients after completion
of their treatment. Posttherapeutically its concentration showed more than 50% reduction in almost all (91.4%) patients (P<0.001).
Importantly these patients had also shown significant regression of the disease clinically and radiologically. 8.6% of patients
had shown static or increase in serum CA125 concentration which was associated with either clinically static or progressive
disease. Recurrence of the disease was noted in patients who had shown increase in serum CA125 concentration (biochemical
recurrence) in the followup
However, in our test population biochemical recurrence(increase in serum marker concentration) preceded the clinical or radiological
recurrence by an average of 6.5 months.
Kaplan meier survival analysis for evaluation of overall survival in our test subjects showed an overall survival of 32% at
one year and median survival of 9 months with confidence interval of 6.34 to 11.66. We conclude that serum CA125 is a useful
marker for monitoring the treatment and predicting an early recurrence of the disease in ovarian carcinoma patients. A study
in larger number of patients is needed to define its exact role in the management of the carcinoma ovary. 相似文献