Abstracts of 42nd National Conference of Association of Clinical Biochemists of India (ACBICON 2015)     

Praveen Sharma  Shailja Chambial  Kamla Kant Shukla 《Indian journal of clinical biochemistry : IJCB》2015,30(1):1-131

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Blood Lead Level (BLL) in the Adult Population of Jodhpur: A Pilot Study     

Shailja Chambial  Kamla Kant Shukla  Shailendra Dwivedi  Pankaj Bhardwaj  Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2015,30(3):357-359

Lead interferes with a variety of body processes and is toxic to many organs and tissues including the heart, bones, intestines, kidneys, and reproductive and nervous systems. Routes of exposure to lead include contaminated air, water, soil, food, and consumer products. The possibility of lead exposure in humans is therefore of great significance from health point of view. Occupational exposure is a common known cause of lead poisoning in adults but current status of adults exposed otherwise is not known. School teachers representing wide local population were selected and asked to furnish information regarding possible lead exposure. Blood lead level (BLL) was estimated using anodic stripping voltammetry. The mean BLL was 6.89 ± 9.5 μg/dl (<3.5–>65 μg/dl) in representative adult population. Out of the total 16 % were found to be having BLL >10 μg/dl which has significantly decreased from leaded gasoline era. Those with increased BLL (>10 μg/dl) were found to have common determinants like usage of old metallic pipes for plumbing, water consumption without any purification system, usage of cosmetics and Ayurvedic/herbal medicines.  相似文献   

A metric measure for direct comparison of competing models in covariance structure analysis     

Ajith Kumar  Subhash Sharma 《Structural equation modeling》2013,20(2):169-197

Comparing the fit of alternative models has become a standard procedure for analyzing covariance structure analysis. Comparison of alternative models is typically accomplished by examining the fit of each model to sample data. It is argued that rather than using this indirect approach, one should do direct comparisons of the similarities and differences among competing models. It is shown that among the existing good‐ness‐of‐fit indexes, the root mean square residual (RMSR) is the only one that can be used for this purpose. However, the RMSR fails to satisfy some important statistical desiderata. Rao's Distance (RD), an alternate measure, is shown to overcome this limitation of RMSR. The preference for RD over RMSR for model comparisons is illustrated through a detailed analysis of a particular sample of multitrait‐multimethod data. A simulation study conducted to empirically investigate the sampling behavior of RD reveals that the true orderings of intermodel proximities are recovered (on average) with a fair degree of accuracy.  相似文献   

澳大利亚的融合教育支持体系——维多利亚州的模式     

刘鲲  杨广学  Umesh Sharma 《中国特殊教育》2012,(9):13-17

本文以维多利亚州为例,概括、分析了澳大利亚融合教育的法律、政策框架和发展趋势,分析了维多利亚州以“教和学”为核心的服务体系、“一体化”的融合教育服务模式和跨学科的专业服务模式,讨论了融合教育发展与普通教育体系变革之间的深刻联系.  相似文献   

Effect of Growth Hormone on Plasminogen Activator and Inhibitor Activity in Rat     

P. Bubber  A. Sharma  A. Chauhan  D. D. Bansal 《Indian journal of clinical biochemistry : IJCB》2013,28(2):193-196

Growth retardation is one of the significant changes in chronic kidney disease (CKD) and is associated with increased morbidity and mortality. Disturbances in growth hormone (GH) are held responsible for several complications in CKD. GH is a protein based peptide hormone which directly or indirectly regulates renal functions to ensure homeostasis. We investigated the effects of growth hormone on plasminogen activators (PA) in rat kidney, PA and plasminogen activator inhibitor (PAI), glucose and fibrinogen in plasma and serum lipid profile. Rats were injected daily with 250 mU GH kg-1 body weight subcutaneously for one week. Growth hormone treatment increased PA activity significantly in rat kidneys as compared to controls. No changes were seen in PA, PAI and fibrinogen levels in the plasma of two groups of rats. There was significant decrease in plasma glucose, total cholesterol and LDL-cholesterol levels in serum of treated group resulting in the decrease of HDL/LDL and total cholesterol/cholesterol ratios. However, triglycerides and VLDL showed significant higher activity in the serum of treated group as compared to controls. Our data suggests that GH administration might improve renal function by increasing PA activity in kidney as well as by reducing the cholesterol content in blood. GH may be effective in improving growth failure as it helps to maintain the normal homeostatic balance.  相似文献   

Diagnostic Value of PCR in Genitourinary Tuberculosis     

Narotam Sharma  Veena Sharma  Prem Raj Singh  Shivani Sailwal  Rajeev S. Kushwaha  Rajesh K. Singh  Satish C. Nautiyal  Pankaj Mishra  Tariq Masood  R. K. Singh 《Indian journal of clinical biochemistry : IJCB》2013,28(3):305-308

Genitourinary tuberculosis is a disease of the genitourinary system which includes the entire urinary tract and reproductive system. Genital tuberculosis is an important cause of female infertility, especially in developing nations like India. In the present study, a total of 257 clinical specimens comprising of endometrial biopsy (109), endometrial curetting (42), menstrual blood (8), semen (17), placenta (11) and urine (70) were collected from patients and subjected for PCR, Culture and AFB detection. The endometrial biopsy, endometrial curetting, menstrual blood, semen, placenta, urine showed 30.2, 45.2,12.5, 5.8, 27.2, 31.4 %, positivity rate for tuberculosis by PCR, 7.3, 9.5, 25.0, 0, 9, 8.5 % by culture and 1.8, 2.3, 0, 0, 0, 2.8 % respectively by AFB smear. Being a novel, rapid technique, PCR is the method of choice for rapid diagnosis and management of genitourinary tuberculosis shared with the other concerned tests. This study reveals that genital tuberculosis can occur in any age group, however, the majority of patients were from reproductive age (nearly 75 % of them were from 20–45 years of age) group.  相似文献   

Standardized testing – By Richard P Phelps     

Ramesh C. Sharma 《British journal of educational technology : journal of the Council for Educational Technology》2009,40(3):590-591

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Pittendrigh: The darwinian clock-watcher     

Vijay Kumar Sharma 《Resonance》2006,11(5):32-41

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Neural network approach to predict mobile learning acceptance     

Hafedh Al-Shihi  Sujeet Kumar Sharma  Mohamed Sarrab 《Education and Information Technologies》2018,23(5):1805-1824

The proliferation of mobile computing technologies is playing major role in the growth of mobile learning (M-learning) market around the globe. The purpose of this paper is to develop a research model in the lines of commonly used models the Unified Theory of Acceptance and Use of Technology (UTAUT) and Technology Acceptance Model (TAM) by incorporating constructs namely flexibility learning, social learning, efficiency learning, enjoyment learning, suitability learning, and economic learning that can predict M-learning adoption in a developing country. The data were collected from 388 students from all major universities/colleges in the capital city (Muscat) of Oman. The neural network modeling was employed to predict M-learning adoption. The neural network modeling results showed that flexibility learning, social learning, efficiency learning, enjoyment learning, suitability learning, and economic learning variables have significant influence on the intention of students to accept mobile learning. The key outcomes of this study suggest important determinants that can assist academic administrators and telecommunication service providers to enhance the adoption of M-learning with the help of suitable strategy.  相似文献   

Studies on the management of root-knot nematode, Meloidogyne incognita -wilt fungus, Fusarium oxysporum disease complex of green gram, Vigna radiata cv ML-1108     

Haseeb Akhtar  Sharma Anita  Shukla Prabhat Kumar 《Journal of Zhejiang University. Science. B》2005,6(8):736-742

Studies were conducted under pot conditions to determine the comparative efficacy of carbofuran at 1 mg a.i./kg soil, bavistin at 1 mg a.i./kg soil, neem (Azadirachta indica) seed powder at 50 mg/kg soil, green mould (Trichoderma harzianum) at 50.0 ml/kg soil, rhizobacteria (Pseudomonas fluorescens) at 50.0 ml/kg soil against root-knot nematode,Meloidogyne incognita-wilt fungus,Fusarium oxysporum disease complex on green gram,Vigna radiata cv ML-1108. All the treatments significantly improved the growth of the plants as compared to untreated inoculated plants. Analysis of data showed that carbofuran andA. indica seed powder increased plant growth and yield significantly more in comparison to bavistin andP. fluorescens. Carbofuran was highly effective against nematode, bavistin against fungus,A. indica seed powder against both the pathogens and both the bioagents were moderately effective against both the pathogens.  相似文献