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Nidhi Sharma Veena Garg Arpita Paul 《Indian journal of clinical biochemistry : IJCB》2010,25(2):193-200
Alloxan administration in male Swiss albino mice, induced diabetes by increasing blood glucose concentration and reducing
hepatic glycogen content as compared to normal control group. Besides, serum lipid profile parameters such as total-cholesterol,
triglyceride, low-density lipoprotein and very low-density lipoprotein-cholesterol were also elevated, whereas, the level
of high-density lipoprotein-cholesterol was reduced significantly (P<0.05) in diabetic mice. Treatment of diabetic animals
with crude ethanolic extract of bark of Prosopis cineraria (P. cineraria) for 45 days, significantly lowered blood glucose
level, elevated hepatic glycogen content and maintained body weight and lipid-profile parameters towards near normal range.
Declined activity of antioxidant enzymes and concentration of non-enzymatic antioxidants were also normalized by drug treatment,
thereby reducing the oxidative damage in the tissues of diabetic animals and hence indicating the anti-diabetic and antioxidant
efficacy of the extract. 相似文献
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P. R. Sharma S. Jain R. N. K. Bamezai P. K. Tiwari 《Indian journal of clinical biochemistry : IJCB》2010,25(1):57-63
The present study was carried out in the Sahariya tribe of Central India, which reportedly have high prevalence of pulmonary
tuberculosis. Total serum LDH and its tissue specific isoforms were estimated in TB patients and matched healthy controls
to test the utility of LDH as diagnostic marker for tuberculosis. About 210 sputum positive cases and 328 age and sex matched
sputum negative controls were recruited. The spectrophotometeric and densitometric analysis of each LDH isoform was carried
out in both cases and controls. The mean values of serum LDH were estimated and compared for each class by t-test. The statistical
comparisons were made between sputum negative controls and sputum positive cases by Mann-Whitney’s U test. The spectrophotometric
estimation of serum LDH revealed significant (P=0.0016) increase in its level in cases (290 IU/L) as compared to controls
(248 IU/L). The densitometric analysis of individual LDH isoforms in cases and controls demonstrated significant elevation
in LDH1 (P>0.05), LDH2 (P>0.05) and LDH3 (P<0.005) in sputum positive cases in comparison to sputum negative controls. Our
study revealed a positive correlation between serum LDH level and the presence of mycobacteria and their load, suggesting
utility of LDH as an important diagnostic marker of tuberculosis induced stress, at least in tribal areas lacking access to
modern clinical tests. 相似文献
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Jordan A. Tanner Beeran Jethwa Jeff Jackson Maria Bartanuszova Thomas S. King Arunabh Bhattacharya Ramaswamy Sharma 《Anatomical sciences education》2020,13(5):568-580
The pterygopalatine fossa (PPF) is a bilateral space deep within the skull that serves as a major neurovascular junction. However, its small volume and poor accessibility make it a difficult space to comprehend using two-dimensional illustrations and cadaveric dissections. A three-dimensional (3D) printed model of the PPF was developed as a visual and kinesthetic learning tool for completely visualizing the fossa, its boundaries, its communicating channels, and its neurovascular structures. The model was evaluated by analyzing student performance on pre- and post-quizzes and a student satisfaction survey based on the five-point Likert scale. The first cohort comprised of 88 students who had never before studied the PPF. The second cohort consisted of 30 students who were previously taught the PPF. Each cohort was randomly divided into a control group who were provided with a half skull and an intervention group that were provided with the 3D printed model. The intervention group performed significantly better on the post-quiz as compared to the control group in cohort I (P = 0.001); while not significant, it also improved learning in cohort II students (P = 0.124). Satisfaction surveys indicated that the intervention group found the 3D printed model to be significantly more useful (P < 0.05) as compared to the half skull used by the control group. Importantly, the effect sizes for cohorts I and II (0.504 and 0.581, respectively) validated the statistical results. Together, this study highlights the importance of 3D printed models as teaching tools in anatomy education. 相似文献
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Nimmi Sharma 《Resonance》2011,16(1):38-46
Laser radar, also called lidar, is proving to be a powerful technique for helping us to understand the world in which we live.
It can provide information on topography, vegetation canopies, and on characteristics of Earth’s atmosphere. This article
describes how laser light scattering can be used in lidar systems to help visualize the structure of our atmosphere and to
address a wide variety of important scientific questions from air pollution to climate issues. The article focuses on two
specific examples of ground-based elastic lidar, the Micro Pulse Lidar System and the CLidar system, to provide an introduction
to the methods of atmospheric lidar measurements and their applications. 相似文献
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The University of the South Pacific is owned by 12 nations in the South Pacific Ocean. The institution provides higher education through its 14 campuses, with at least 1 campus per member country. To be able to overcome the geographical divide and isolation, while ensuring high-quality learning and teaching, the university utilizes Internet, satellite, and mobile devices and other Information and Communications Technology (ICT) tools and technologies to provide virtual classroom experience. This article outlines the approaches adopted in offering a first-year chemistry course, in parallel, through face-to-face and distance modes. The novel attributes of bridging the geographical divide are presented. The article concludes with a discussion of new innovations that will further bring the classroom to the student irrespective of where the student is in the world. 相似文献