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41.
42.
Mohana Kumari Chidananda Deepy Zohmangaihi Sant Ram Shiv Lal Soni Vikas Suri Pankaj Malhotra Ravjit Singh Jassal Jyotdeep Kaur Indu Verma Sadhna Sharma 《Indian journal of clinical biochemistry : IJCB》2021,36(4):485
Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a global health problem, India being the second most affected country. The kinetics of antibody response to SARS-CoV-2 in Indian population is not studied yet. To understand serological response in relation to age, gender, time period and severity of disease, Roche Elecsys anti-SARS-CoV-2 test was used which analysed both IgM and IgG. One hundred and three COVID-19 patients were enrolled. Seropositivity was seen in 64% of patients, with 33% at ≤ 7 days, 62% between 8 and 15 days and 81% at ≥ 16 days from the time of admission. Men (65%) showed higher antibody response than women (59%), whereas no difference was observed in seropositivity with respect to age of the patients. Dynamics of antibody responses revealed individual variations. Patients in ICU had higher antibody reactivity with 67% positivity as compared to 60% positivity in non-ICU patients. Kinetics of antibody response during COVID-19 disease varied in relation to gender, age, time period and severity and these factors might play an important role in treatment and control of COVID-19. 相似文献
43.
Amritpal Kaur 《International Information and Library Review》2013,45(4):182-193
The article examines academics attitude towards e-journal use. A well structured questionnaire was designed to elicit the opinions of the users. Responses were gathered from 542 faculty members of five universities. The results of the study showed that the characteristics that affect the choice of e-format over print in order of preference are ‘faster access’, ‘available from desktop’, ‘convenience’, ‘remote access’, ‘timeliness’, ‘available at all times’, ‘hyperlinks’, ‘multi-user access’, ‘currency of information’, ‘inclusion of audio–video material’, ‘interactivity’ and ‘animation of graphics’. The characteristics that affect the choice of print format over electronic in order of priority are ‘physical comfort’, ‘portability’, ‘ability to underline’, ‘familiarity with format’ and ‘ability to browse’. A majority of the teachers use e-journals for ‘research’, ‘teaching’, ‘writing reports’, ‘current awareness’, ‘background research’ and ‘internal/external presentations’. The problems faced in accessing e-journals are ‘access difficulties’, ‘discomfort of reading from computer screen’, ‘lack of IT knowledge/skill’, ‘information overload’ etc. A majority of the teachers want future e-journals to have features such as ‘full text index of every article’, ‘searching capability across a wide range of journal articles’, ‘searching capability within an article, display relationship between a wide range of works’ and ‘links to multimedia files’, etc. On the basis of the findings, some suggestions are made for maximizing the use of e-journals. 相似文献
44.
With a focus on the Hindi language superhero comics produced by Raj Comics since the 1980s, this article investigates instances of “modernities in the backyard” and their implications for studying postcolonial popular culture. The graphic narratives in the comic books are neither simply Westernized or transgressive, nor necessarily framed by a mythicized or Orientalised discursive framework. Instead, they register a distinctive heritage combining vernacular and mythic prototypes with hypermodern visions with which to imagine new powers for Indian men and women, even though women may continue to be shaped by the masculinist, desirous gaze and modulated by patriarchal expectations to do with female docility and marriageability. The enquiry provides unique material to chart out the lineaments of postcolonial culture, gender, and power in order to provincialize the scope of cultural studies. 相似文献
45.
Awang-Hashim Rosna Kaur Amrita Yusof Norhafezah Shanmugam S. Kanageswari a/p Suppiah Manaf Nor Aziah Abdul Zubairi Ainol Madziah Voon Angelina Yee Seow Malek Marzura Abdul 《Higher Education》2022,83(3):635-654
Higher Education - The shift in contemporary workplaces has caused higher education institutions to place importance on developing non-academic attributes along with academic success to help... 相似文献
46.
Bineeta Kashyap Nisha Goyal G. K. Das N. P Singh I. R. Kaur 《Indian journal of clinical biochemistry : IJCB》2018,33(4):483-486
TB as the cause of uveitis varies from 0.5 to 10.5%; low sensitivity of confirmatory laboratory investigations and inconsistency of diagnostic criteria leads to paucity of data. Diagnosis requires a high level of suspicion and is often presumptive based on indirect evidences. Interferon gamma, Interleukin-2 and Neopterin are key biomarkers in immuno-regulation of Mycobacterium tuberculosis infection. The relative shift from Interleukin-2 towards Interferon gamma (Interferon gamma/Interleukin-2) is more discriminatory for active tuberculosis. Protein carbonyl and Malondialdehyde, as oxidative stress markers, characterize active tuberculosis. A case of disseminated TB presenting with acute uveitis had a recurrent tubercular lymphadenitis after completing category I treatment under revised national tuberculosis control programme. The present study evaluates the potential utility of above mentioned biomarkers to predict atypical presentation in difficult cases of tuberculosis. Though tuberculous uveitis is amenable to treatment in early course of disease, the delay in diagnosis can have serious consequences for the patient. 相似文献
47.
Mukesh Nandave S K Ojha Ranjit Kaur 《Indian journal of clinical biochemistry : IJCB》2005,20(2):154-157
The present study deals with estimation of levels of fractions of serum glycoproteins, protein bound hexose (PBH), protein
bound hexosamine (PBHex), protein bound fucose (PBF), protein bound sialic acid (PBS) and protein bound carbohydrate (PBC)
in thirty patients of Major Depressive Disorders (MDD) in comparison with thirty normal subjects. In patients of MDD, the
level of PBH, PBHex, PBF, PBS and PBC were significantly higher as compared to the normal subjects (p<0.05). In patients,
of MDD, after one-month treatment with fluoxetine, the levels of PBH, PBHex, PBF, PBS and PBC were significantly decreased
as compared to the levels of these fractions in same patients of MDD before beginning of the treatment (p<0.05). Based on
findings of the present study, it can be concluded that changes in the level of serum glycoproteins level before and after
treatment with fluoxetine can be correlated with clinical status of MDD. 相似文献
48.
Parneet Kaur Manpreet Singh Gurpreet Singh Josan 《Education and Information Technologies》2017,22(3):965-983
Rank Aggregation techniques have found wide applications for metasearch along with other streams such as Sports, Voting System, Stock Markets, and Reduction in Spam. This paper presents the optimization of rank lists for web queries put by the user on different MetaSearch engines. A metaheuristic approach such as Genetic algorithm based rank aggregation technique has been proposed and implemented in MATLAB for Kendall-tau as (GKTu) and Spearman’s foot rule as (GSFD) distance measures. A comparative analysis has been carried out between ranked lists for with and without GA on the basis of simulated results. From the results it has been found that proposed GA optimized rank list (for a particular query on the basis of minimum distance) is better than the conventional methods. In addition, a word association technique i.e., AND-OR operator has been applied on each query. The results are investigated in comparison to non- logic operators for the same query. 相似文献
49.
Jagdish Kaur Chahil Khamsigan Munretnam Nurulhafizah Samsudin Say Hean Lye Nikman Adli Nor Hashim Nurul Hanis Ramzi Sharmila Velapasamy Ler Lian Wee Livy Alex 《Indian journal of clinical biochemistry : IJCB》2015,30(2):134-139
Genome-wide association studies have discovered multiple single nucleotide polymorphisms (SNPs) associated with the risk of common diseases. The objective of this study was to demonstrate the replication of previously published SNPs that showed statistical significance for breast cancer in the Malaysian population. In this case–control study, 80 subjects for each group were recruited from various hospitals in Malaysia. A total of 768 SNPs were genotyped and analyzed to distinguish risk and protective alleles. A total of three SNPs were found to be associated with increased risk of breast cancer while six SNPs showed protective effect. All nine were statistically significant SNPs (p ≤ 0.01), five SNPs from previous studies were successfully replicated in our study. Significant modifiable (diet) and non-modifiable (family history of breast cancer in first degree relative) risk factors were also observed. We identified nine SNPs from this study to be either conferring susceptibility or protection to breast cancer which may serve as potential markers in risk prediction.
Electronic supplementary material
The online version of this article (doi:10.1007/s12291-013-0414-0) contains supplementary material, which is available to authorized users. 相似文献50.
M. Chandra D. R. Maurya S. Kumar H. Basara A. Ghatak B. L. Tekwani G. Kaur M. K. Misra 《Indian journal of clinical biochemistry : IJCB》2003,18(2):150-153
Despite enormous research in the field of hypertension, its pathophysiology still remains largely unresolved and appears to
be multifactorial. In the present communication, we have analyzed the status of nitric oxide (NO) in the patients with essential
hypertension and age matched controls. We have found that the levels of NO are lowered in essential hypertension. The normalization
of blood pressure by administration of antihypertensive therapy causes rise in the NO level indicating that perturbed NO status
in essential hypertension is reversible. Addition of antioxidant to the antihypertensive drugs causes a further, though non
significant, rise in the levels of NO, suggesting that antioxidants may be combined with antihypertensive drugs as adjunct
in the management of essential hypertension. 相似文献