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The ascendency of neoliberal ideas in education and social policy in the 1980s and 1990s was succeeded in the new millennium by a ‘new’ social democratic commitment with emphases on community empowerment, building social capital and a ‘whole of government’ approach to partnering with civil society to meet community needs. In Australia, this approach has resulted in the development of partnerships between schools and community organisations formed as part of a targeted, holistic approach to service delivery to meet the settlement and educational needs of refugee youth. Drawing on interviews conducted with community workers and government officers involved in the school–community partnerships, we document how these partnerships are working ‘on the ground’ in Queensland schools. We analyse our findings against the international literature on changing notions of neoliberal governance, and discuss the implications of the shift to the ‘partnering state’ for schools and community organisations working with refugee young people. 相似文献
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Parvinder Kaur Sheenu Mathur Meenakshi Sharma Manisha Tiwari K. K. Srivastava Ramesh Chandra 《Indian journal of clinical biochemistry : IJCB》2001,16(2):195-198
In Ayurvedic medicine,Withania somnifera (Ashwagandha) is well known for its anti-stress activity. A passive rat experimental model, where the animals are subjected
to multiple stress of cold, hypoxia, restraint (C-H-R) has been developed to evaluate adaptogenic properties of various fractions
of W. somnifera root extracts. We have carried out extraction of roots of W. somnifera with water and further isolated one
of the active constituents called compound X and also tested its anti-stress activity in C-H-R model. The effect of administration
of W. somnifera water suspension (360 mg/Kg bw) and compound X (20mg/Kg bw) on the fall and recovery of colonic temperature
was noted. There was an increase of ≈38% and ≈54% in the time taken to attain Trec 23°C by rats given a single dose of fresh aqueous suspension and biologically active constituent (Compound X) respectively,
where as decrease in the recovery time to attain Trec 37°C is ≈13% and ≈33% respectively, as compared to control group. It is clear that rats treated with the fresh aqueous suspension
and compound X ofWithania somnifera, could withstand the multiple stress of C-H-R better than control group. 相似文献
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Harbans Lal Kiran Chugh Varinder Saini Jasbinder Kaur A. S. Saini 《Indian journal of clinical biochemistry : IJCB》1992,7(2):143-146
Activities of antioxidant enzymes involved oxygen free radical metabolism in the liver and lung were investigated in 2,4, and 30 months old Wistar albino rats. The levels of SOD, GSH-Px, GSH and protein-SH were decreased whereas MDA increased, in the liver as well as the lung of the old rats (30 months old) compared to the young rats (2 and 4 months old). The data suggests that the failure of the free radical protective mechanism may be one of the important contributors to the process of ageing. 相似文献
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Maedeh Roushan Parminder Kaur Alena Karpusenko Preston J. Countryman Carlos P. Ortiz Shuang Fang Lim Hong Wang Robert Riehn 《Biomicrofluidics》2014,8(3)
We present an analytic technique for probing protein-catalyzed transient DNA loops that is based on nanofluidic channels. In these nanochannels, DNA is forced in a linear configuration
that makes loops appear as folds whose size can easily be quantified. Using this technique, we study
the interaction between T4 DNA ligase and DNA. We find that T4 DNA ligase binding changes the physical characteristics of the DNA
polymer, in particular
persistence length and effective width. We find that the rate of DNA fold unrolling is significantly reduced
when T4 DNA ligase and ATP
are applied to bare DNA.
Together with evidence of T4 DNA ligase bridging two different segments of DNA based on AFM imaging, we thus conclude that ligase
can transiently stabilize folded
DNA configurations by coordinating genetically distant DNA stretches. 相似文献
88.
Vikram Thakkar Purvi Patel Neelam Prajapati Ranjit Kaur Mukesh Nandave 《Indian journal of clinical biochemistry : IJCB》2014,29(3):345-350
Identification of reliable biomarkers for detection and staging of cancer and monitoring the outcome of anticancer therapy has been considered to be of high importance. We aimed to estimate the levels of serum glycoproteins, protein bound-hexose, protein bound hexosamine, protein bound fucose, protein bound sialic acid and protein bound carbohydrate in 32 ovarian cancer patients and compared them with the levels that found in 25 normal subjects. As compared to the normal subjects, all the four fractions of glycoproteins level were significantly elevated in ovarian cancer patients (p < 0.05). Chemotherapy in these patients significantly decreased the levels of serum glycoproteins (p < 0.05). Thus, high levels of serum glycoproteins in ovarian cancer patients could be due to abnormal protein glycosylation indicating malignant transformation of the cells. 相似文献
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Indu Verma Satinder Kaur Subash Goyal Shweta Goyal J. S. Multani A. P. S. Narang 《Indian journal of clinical biochemistry : IJCB》2014,29(3):382-385
The supply of oxygen is limited in certain intra abdominal conditions due to direct vascular invasion or inflammatory process, resulting in high lactate levels. Aim of this study was to find the predictive value of lactate levels in the peritoneal fluid (PF) and blood of patients with acute abdomen. The study comprised of fifty patients with acute abdominal conditions, admitted in emergency ward of tertiary care hospital, thirty patients were with surgical abdomen (group I) and twenty patients with non surgical abdomen (group II). Lactate was estimated in PF and blood on Blood Gas Analyzer (NOVA, M-7). The mean lactate levels in PF were significantly higher in group I as compared to group II (14.65 ± 1.195 vs. 5.92 ± 0.97 mmol/L, p < 0.001). There was no significant difference in blood lactate levels in both the groups. When PF and blood lactate levels were compared within groups, we found that PF levels were significantly higher than blood in group I (14.65 ± 1.195 vs. 3.85 ± 0.54 mmol/L, p < 0.001) but not in group II (5.92 ± 0.97 vs. 4.36 ± 0.95 mmol/L). Diagnostic value was obtained using ROC curve. Cut off values obtained for PF lactate, difference and ratio of PF and blood lactate (≥6.4 mmol/L, ≥3.3 and ≥2.1 respectively) are at very high degree of sensitivity and specificity. So it can be useful marker of surgical emergency in patients with acute intra abdominal pathology, especially in clinically ill patients or in whom physical examination is not yielding because of neurologic disorders or unresponsiveness. 相似文献
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