首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   693篇
  免费   4篇
  国内免费   2篇
教育   493篇
科学研究   73篇
各国文化   4篇
体育   42篇
文化理论   13篇
信息传播   74篇
  2020年   5篇
  2019年   6篇
  2018年   12篇
  2017年   11篇
  2016年   16篇
  2014年   7篇
  2013年   212篇
  2012年   9篇
  2011年   11篇
  2010年   9篇
  2009年   14篇
  2008年   13篇
  2007年   12篇
  2005年   10篇
  2003年   11篇
  2002年   6篇
  2001年   8篇
  2000年   10篇
  1999年   10篇
  1998年   9篇
  1997年   12篇
  1996年   6篇
  1995年   5篇
  1994年   4篇
  1993年   13篇
  1992年   10篇
  1991年   6篇
  1990年   6篇
  1989年   4篇
  1988年   10篇
  1987年   11篇
  1986年   14篇
  1985年   7篇
  1984年   7篇
  1983年   11篇
  1982年   13篇
  1981年   5篇
  1980年   8篇
  1979年   8篇
  1978年   5篇
  1977年   8篇
  1975年   10篇
  1974年   8篇
  1973年   7篇
  1971年   6篇
  1970年   6篇
  1969年   7篇
  1968年   4篇
  1925年   5篇
  1924年   5篇
排序方式: 共有699条查询结果,搜索用时 140 毫秒
11.
12.
13.
Obesity is a disease that has become an epidemic in economically developed countries,and manifests itself at increasing rates in economically developing countries.Obesity is associated with a variety of comorbidities,such as metabolic disease,diabetes,cardiovascular diseases,and musculoskeletal disorders,all resulting in tremendous costs to health care systems around the world,a reduced capacity for work,and reduced quality of life for people with obesity,coupled with physical inactivity,thereby producing a vicious circle of inactivity-induced diseases that enhances obesity.  相似文献   
14.
Background:Osteoarthritis is one of the leading causes of pain and disability worldwide,and a large percentage of patients with osteoarthritis are individuals who are also obese.In recent years,a series of animal models have demonstrated that obesity-inducing diets can result in synovial joint damage(both with and without the superimposition of trauma),which may be related to changes in percentage of body fat and a series of low-level systemic inflammatory mediators.Of note,there is a disparity between whether the dietary challenges commence at weaning,representing a weanling onset,or at skeletal maturity,representing an adult onset of obesity.We wished to evaluate the effect ofthe dietary exposure time and the age at which animals are exposed to a high-fat and high-sucrose(HFS) diet to determine whether these factors may result in disparate outcomes,as there is evidence suggesting that these factors result in differential metabolic disturbances.Based on dietary exposure time,we hypothesized that rats fed an HFS diet for 14 weeks from weaning(HFS Weanling) would demonstrate an increase in knee joint damage scores,whereas rats exposed to the HFS diet for 4 weeks,starting at 12 weeks of age(HFS Adult) and rats exposed to a standard chow diet(Chow)would not display an increase in knee joint damage scores.Methods:Male Sprague-Dawley rats were fed either an HFS diet for 14 weeks from weaning(HFS Weanling) or an HFS diet for 4 weeks,starting at 12 weeks of age(HFS Adult).At sacrifice,joints were scored using the modified Mankin Criteria,and serum was analyzed for a defined subset of inflammatory markers(Interleukin-6,leptin,monocyte chemoattractant protein-1,and tumor necrosis factorα).Results:When the HFS Weanling and HFS Adult groups were compared,both groups had a similar percent of body fat,although the HFS Weanling group had a significantly greater body mass than the HFS Adult group.The HFS Weanling and HFS Adult animals had a significant increase in body mass and percentage of body fat when compared to the Chow group.Although knee joint damage scores were low in all 3 groups,we found,contrary to our hypothesis,that the HFS Adult group had statistically significant greater knee joint damage scores than the Chow and HFS Weanling groups.Furthermore,we observed that the HFS Weanling group did not have significant differences in knee joint damage scores relative to the Chow group.Conclusion:These findings indicate that the HFS Weanling animals were better able to cope with the dietary challenge of an HFS diet than the HFS Adult group.Interestingly,when assessing various serum proinflammatory markers,no significant differences were detected between the HTS Adult and HFS Weanling groups.Although details regarding the mechanisms underlying an increase in knee joint damage scores in the HFS Adult group remain to be elucidated,these findings indicate that dietary exposure time maybe less important than the age at which an HFS diet is introduced.Moreover,increases in serum proinflammatory mediators do not appear to be directly linked to knee joint damage scores in the HFS Weanling group animals but may be partially responsible for the observed knee joint damage in the adults over the very short time of exposure to the HFS diet.  相似文献   
15.
It has been several years since the concept of performance technology was introduced in the literature. This article describes how the Instructional Systems program at Florida State University has responded to the changes that are required to expand its orientation from instructional technology to performance technology. Gradual changes in several existing courses and the implementation of two new courses in performance systems analysis and electronic performance support systems are described. In the new courses, students interact with clients to determine needs, examine processes, design solutions, and determine returns on investments. Consideration is also given in the article to ways other universities might respond to the changes in the direction of the field.  相似文献   
16.
17.
Public Law 94-142, Education for All Handicapped Children Act, has had a dramatic impact on the schooling of exceptional children. Yet, rather limited attention has been directed to the one section of the law that mandates a particular decision-making approach for both the diagnosis and intervention tasks. The implications for the training and practice of applied psychologists who work with school-age children could be significant. This paper examines three areas of concern that impact the psychologist's role in working with exceptional children: (a) conditions that are considered crucial for the development of teams, (b) the literature regarding psychologists' input to school-based teams, and (c) reactions of school-based team members to such an approach. Related issues of importance to both trainers and practitioners in the field of psychology are then presented.  相似文献   
18.
Eccentric exercise has been associated with an increase in serial sarcomere number in some studies,1 but not in others.2 Similarly,increasing excursion of muscles resulted in sarcomerogenesis in some studies using growing animals,3 but not in others using skeletally mature animals.4 However,chronic elongation and chronic shortening appears to be a strong regulator of sarcomere number increase5,6 and decrease,5,7 respectively,in animal models.Despite an abundance of research on the regulation of sarcomerogenesis under a variety of conditions,the mechanisms underlying in series sarcomere number adaptations in skeletal muscles remain a puzzle,especially in non-invasive human studies where measurements of sarcomerogenesis following interventions have not been possible to date.  相似文献   
19.
Valdivia WD 《Minerva》2011,49(1):25-46
Evaluation studies of the Bayh-Dole Act are generally concerned with the pace of innovation or the transgressions to the independence of research. While these concerns are important, I propose here to expand the range of public values considered in assessing Bayh-Dole and formulating future reforms. To this end, I first examine the changes in the terms of the Bayh-Dole debate and the drift in its design. Neoliberal ideas have had a definitive influence on U.S. innovation policy for the last thirty years, including legislation to strengthen patent protection. Moreover, the neoliberal policy agenda is articulated and justified in the interest of “competitiveness.” Rhetorically, this agenda equates competitiveness with economic growth and this with the public interest. Against that backdrop, I use Public Value Failure criteria to show that values such as political equality, transparency, and fairness in the distribution of the benefits of innovation, are worth considering to counter the “policy drift” of Bayh-Dole.  相似文献   
20.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号