运动对RBP4诱导的脂代谢异常鼠肝脏ACC1 表达和脂肪合成的影响          下载免费PDF全文

张明军 《河北体育学院学报》2017,31(1):54-59

目的:研究运动对RBP4诱导的脂代谢异常鼠肝脏ACC1表达和脂肪合成的影响.方法:重组人RBP4注射建立脂代谢异常鼠模型.设一次性运动组(RBP4 One-time exercise group,ROE 组)、8周有氧运动组(RBP4 aerobic exercise group,RAE组)和安静对照组(RBP4 control group,RC组).结果:ROE组血清RBP4水平与RC组相比显著降低(P＜0.05),血清TG和肝脏TG含量无显著改变(P＞0.05).RAE组血清RBP4、TG和肝脏TG含量与RC组和ROE组相比均显著降低(P＜0.01).与RC组相比,ROE组和RAE组肝脏ACC1mRNA表达均显著降低(P＜0.01).与RC组相比,ROE组ACC1蛋白表达无显著改变(P＞0.05).与RC组和ROE组相比,RAE组ACC1蛋白表达均显著降低(P＜0.01).结论:高RBP4显著增加小鼠肝脏ACC1基因和蛋白表达增加,促进肝脏脂肪合成.8周有氧运动抑制了RBP4在肝脏的脂肪合成促进作用,改善脂代谢,机制涉及降低RBP4水平、减少肝脏ACC1基因和蛋白表达以及TG的合成.  相似文献   

The Saljuq Turks’ Conversion to Islam: The Crusading Sources     

Nicholas Morton 《Al-Masaq: Islam & the Medieval Mediterranean》2015,27(2):109-118

This article contributes to the important debate over the conversion of the Turks to Islam. Previously, it was thought that the Turks abandoned their former steppe faith and customs very swiftly to become staunch Sunni Muslims, but this view has recently been challenged by a number of studies. The current consensus seems to be that the Turks’ adoption of Islam was a process of far longer duration, spanning many decades. This article broadens this discussion by demonstrating that the chronicles written by the First Crusaders contain much useful information that is pertinent to this question. It works through these texts, showing that they can shed new light on this point.  相似文献   

基于负样本多通道优化SSD网络的钢铁厂提取     

卢凯旋  李国清  陈正超  昝露洋  李柏鹏  高建威 《中国科学院大学学报》2020,37(3):352-359

准确提取钢铁厂对去产能监测和环境保护具有重要意义。传统的人工目视解译方法效率低、成本高,无法满足开展大区域钢铁厂监测的需求。以深度学习目标检测网络SSD为基础,构建面向遥感影像钢铁厂提取的深度学习目标检测网络,提出maxout模块,将负样本通路优化为多分支结构,突出难分负样本特征并提升网络对无用特征的抵制效果。利用国产GF-1数据对京津冀地区的钢铁厂进行快速自动提取实验。与人工解译的钢铁厂点位数据的对比表明,该目标检测方法的提取精度达到80%以上。  相似文献   

Why super sandstorm 2021 in North China?     

Zhicong Yin  Yu Wan  Yijia Zhang  Huijun Wang 《国家科学评论(英文版)》2022,9(3)

Severe sandstorms reoccurred in the spring of 2021 after an absence for more than 10 years in North China. The dust source area, located in Mongolia, suffered destructive cooling and warming in early and late winter, which loosened the land. A lack of precipitation, excessive snow melt and strong evaporation resulted in dry soil and exiguous spring vegetation. A super-strong Mongolian cyclone developed on the bare and loose ground, and easily blew and transported large amounts of sand particles into North China. Furthermore, top-ranking anomalies (sea ice shift in the Barents and Kara Sea, and sea surface temperatures in the east Pacific and northwest Atlantic) were found to induce the aforementioned tremendous climate anomalies in the dust source area. Analyses, based on large-ensemble Coupled Model Intercomparison Project Phase 6, yield results identical to the reanalysis data. Thus, the climate variabilities at different latitudes and synoptic disturbances jointly facilitated the strongest spring sandstorm over the last decade.  相似文献   

Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53     

Min LI  Yidan SU  Xiaoyuan GAO  Jiarong YU  Zhiyong WANG  Xiqiao WANG 《Journal of Zhejiang University. Science. B》2022,23(3):204

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AQP-1和AQP-5在卵巢上皮性肿瘤的表达及临床意义     

杨建华  石一复  周彩云  王国萍 《科技通报》2006,22(6):781-784,791

目的探讨AQP1及AQP5在卵巢上皮性肿瘤的表达及临床意义。方法采用免疫组化法检测105例卵巢上皮性肿瘤和10例正常卵巢组织AQP1和AQP5蛋白的表达。结果AQP1主要表达于毛细血管及小血管内皮细胞．而AQP5表达于卵巢肿瘤细胞。随着卵巢上皮性肿瘤由良性向恶性发展,AQP1和AQP5的表达逐渐增加（P〈0．05）。Ⅲ、Ⅳ期卵巢癌AQP1的表达明显高于Ⅰ、Ⅱ期（P〈0．05）,伴淋巴转移者AQP1明显高于无淋巴转移者（／9〈0．05）;腹水大于1000mL者AQP1和AQP5的表达明显高于小于1000mL者（P〈0．01）：低分化卵巢癌AQP5的表达明显高于高、中分化者（P〈0．05）;AQP1及AQP5的表达与腹水量呈正相关（r分别为0．40,0.31;P〈0．05）。结论AQP1和AQP5高表达与卵巢癌的发生、发展及预后有关,可能是卵巢癌腹水产生的主要原因。  相似文献   

IRON DETERMINATION AFTER ON-LINE SORBENT PRECONCENTRATION BY FI-FASS USING 1,10-PHENANTHROLINE AS A COMPLEXING AGENT     

Akbar Ali  叶映雪  徐光明  张涛  殷学锋  金鑫 《Journal of Zhejiang University. Science. B》2000,(1)

ＩＮＴＲＯＤＵＣＴＩＯＮＯｎ ｌｉｎｅｓｅｐａｒａｔｉｏｎａｎｄｐｒｅｃｏｎｃｅｎｔｒａｔｉｏｎｈａｖｅｒｅｃｅｉｖｅｄｃｏｎｓｉｄｅｒａｂｌｅａｔｔｅｎｔｉｏｎｉｎｆｌｏｗｉｎｊｅｃｔｉｏｎａｎａｌｙｓｉｓｃｏｕｐｌｅｄｗｉｔｈａｔｏｍｉｃａｂｓｏｒｐｔｉｏｎｓｐｅｃ ｔｒｏｍｅｔｒｙｄｕｒｉｎｇｒｅｃｅｎｔｙｅａｒｓａｎｄｉｓｗｉｄｅｌｙａｐ ｐｌｉｅｄｆｏｒｓｅｌｅｃｔｉｖｉｔｙａｎｄｓｅｎｓｉｔｉｖｉｔｙｅｎｈａｎｃｅｍｅｎｔ(Ｆａｎｇ ,1 995 ) .Ａｕｔｏｍａｔｉｏｎｏｆｔｈｅｓａｍｐｌｅｐ…  相似文献   

邢慧娜1 500 m不同运动阶段技术特征的研究     

李美霞  李厚林 《西安体育学院学报》2007,24(6):82-86

运用实验法、文献法、专家访谈法等对邢慧娜参加奥运会预选赛的现场技术资料,通过量化分析获得运动技术指标,结合运动训练实际,对邢慧娜1 500 m不同阶段的动作技术进行分析。结果表明:邢慧娜在加速度阶段表现出步长大、步频低的运动特点,着地腿"扒地"积极、着地角大、进入比赛状态慢的特点;途中跑阶段体现了"低抬摆快"技术特点;髋部轴心大肌肉群发力特点;冲刺阶段缓冲时间短,摆动腿送髋幅度大、"屈蹬"技术特点;全程表现出"步幅-速度型"技术特征。  相似文献   

保密信息传输的数字签名方案研究     

肖长水  高觐悦 《苏州市职业大学学报》2007,18(3):61-63

结合非对称密码体制和对称密码体制的优点,设计了保密信息传输的基于混合密码算法的数字签名方案,并给出了基于Java Applet技术的详细实现过程。通过对该方案的安全性分析可知,该数字签名方案较好地保证了信息传输的机密性、完整性和不可抵赖性。  相似文献   

健美操剪式变身跳转体180°起跳阶段技术分析   总被引：2，自引：0，他引：2  

许春利  赵卓然  范美艳 《北京体育大学学报》2007,30(9):1292-1294

从研究方法和研究内容着手,以剪式变身跳转体180°起跳阶段技术分析为突破口,运用运动生物力学手段对健美操动作进行深入、细致的研究,为综合评价运动员的技术水平提供理论依据.  相似文献