单核细胞增多性李斯特菌RsbR抗酸应激机制（英文）     

Ke He  Yong-Ping Xin  Ying Shan  Xian Zhang  Hou-Hui Song  Wei-Huan Fang 《Journal of Zhejiang University. Science. B》2019,(8):660-669

目的:探明单增李斯特菌RsbR的两个保守磷酸化位点是否影响SigB(sigmaB)的表达.创新点:解析了RsbR在单增李斯特菌中SigB网络调控中的作用.方法:通过基因缺失、定点突变和回补技术构建rsbR基因缺失株、回补株和回补突变菌株,进行酸应激条件下的生长能力和强酸条件下的存活能力试验,并检测在酸应激下菌株中的SigB基因和蛋白表达的改变情况.结论:RsbR缺失能够显著降低单增李斯特菌的抗酸应激能力和下调SigB表达,RsbR-175位点是SigB调控途径中RsbT释放的先决条件.  相似文献   

学报创办60期誌言     

《潍坊教育学院学报》编辑部 《潍坊教育学院学报》2006,19(2):103-104

本文认真回顾思考创办院刊学报19年60期来的经验,总结在农村基层办教育学术期刊的特殊规律和做法,并分析此类杂志在新时期所面临的挑战及对策。  相似文献   

中德近代高等教育发展进程比较     

冯超英  丁平 《内蒙古大学学报(人文社会科学版)》2002,34(1):115-118

德国高等教育的近代发展是从大学的革新开发的，各种专门学院是在大学教育发展到一定阶级后才得到显的发展。中国近代高等教育的发展是从专门教育的兴起开始的，大学建立后大学教育成了高等教育的主要组成部分。两国在发展近代高等教育过程中所走的道路，所采取的政策，既存在着某些差别，又有一些相似之处。  相似文献   

提高国民生活质量和国家竞争力——韩国新世纪的人力资源开发战略简析     

孙文正 《外国教育研究》2005,32(10):35-38

韩国政府为了实现在21世纪成为“世界超一流国家”的宏伟目标，在对现存教育与人力资源开发体制进行反省的基础上，决定把强化人力资源开发作为国家发展的核心战略。2001年12月制定出台了《人、知识、跨越：国家人力资源开发基本计划》，确立了“提高国民生活质量和国家竞争力”的人力资源开发目标和一系列政策保障措施。  相似文献   

三层C/S结构报刊发行信息系统的设计实现     

杜冬梅  盖建荣  吴梅娟 《石家庄职业技术学院学报》2007,19(6):37-40

阐述了三层C/S体系结构的优点,Tuxedo中间件的主要功能和特点.介绍了在Linux操作系统下基于Tuxedo的三层C/S体系结构的报刊发行信息系统的设计与实现.  相似文献   

Keeping things different: coexistence within European markets for cleantech and biofuels     

Liliana Doganova  Brice Laurent 《Journal of Cultural Economy》2016,9(2):141-156

Environmental policy increasingly resorts to market-based instruments in order to meet sustainability objectives. The ‘carbon market’ instituted by the European Emissions Trading directive from 2003 is a canonical example, which has been described, and critiqued, as a delegation of policy objectives to market exchanges. In this paper, we examine the complex ways in which the operationalization of policy objectives and the organization of markets are intertwined, focusing on two other examples of European environmental regulation. The first one is the Integrated Pollution Prevention and Control directive from 1996, which defined the ‘best available techniques’ to curb emissions in air, water and soil. The second one is the Renewable Energy Directive from 2009, which introduced criteria for the definition of the sustainability of biofuels. Through the analysis of the design and implementation of these two directives, we identify a central concern for the coexistence of various objects, and various initiatives undertaken by European institutions, member states and private actors. We use the notion of coexistence to describe a European political and economic ordering that is inherently hybrid, and cannot be reduced to a mere delegation of policy objectives to the market, or a legal constraint imposed on all European actors. It grounds its political legitimacy and economic rationality on the distribution of roles and responsibilities across public and private actors, and on the ability to ‘keep things different’ according to local variabilities.  相似文献   

What price evidence? The ethics of office and the ethics of social science in British cultural policy     

Dave O'Brien 《Journal of Cultural Economy》2016,9(2):127-140

This paper considers the use of evidence for government decision-making using ethnographically informed data from the lived experiences of those involved in British cultural policy. It does this in order to engage and extend work that has sought to defend bureaucratic forms of activity. The paper offers an empirical case study of how the civil servants’ ethic of office [DuGay, P. (2008) ‘Max weber and the moral economy of office’, Journal of Cultural Economy, vol. 1, no. 2, pp. 129–144] is reinforced by the identity of the social scientist. The use of social science in policy advice is a moment where the bureaucrats are able to distance themselves from political decision-making, thus reasserting an important aspect of civil service practice and identity. However, as the latter part of the article illustrates, the dynamics of cultural policy-making, in particular the use of economics, situate the role of social science as paradoxical. It is both supportive and corrosive of the bureaucratic ethic. This paradox is the basis for a critical perspective on the ethic of office as deployed in contemporary government.  相似文献   

Re-Envisioning E-Resource Holdings Management     

Marlene van Ballegooie 《期刊图书馆员》2016,70(1-4):135-148

For e-resource librarians, maintaining e-book and e-journal holdings within electronic resource management systems is a labor intensive and often manual process. In 2014, with the aim of saving library staff valuable time and effort, the Online Computer Library Center, Inc. (OCLC) launched a service to provide automated holdings management within the WorldCat knowledgebase. For a select group of content providers, including some of the largest e-book aggregators, holdings information can be populated and updated automatically within the knowledgebase without intervention from library staff. At the University of Toronto Libraries, we conducted a study to assess the accuracy and efficiency of these automated holdings management services. This presentation outlines the results of the study and provides suggestions for further improvement to the current services offered.  相似文献   

中国现代思想史上的"陶胡分歧"     

吴翔 《南京晓庄学院学报》2006,22(5):9-16,56

陶行知与胡适的分歧贯穿了五四之后的近三十年中国现代思想史上的大事。二人之间的最初教育分歧不在教育观点本身,而是“教育界分歧”,始于1926年“庚款风波”;其次是30年代的政治9牾,基于两种基本爱国观的难于兼容,但非以政见分歧为主要内容;其三,双方主要的、根本的分歧是30年代形成的关于基本价值观——五四价值观的分歧。陶推崇一二九“大众”运动,反思并批判五四“小众”运动;由此出发,陶形成了自己的大众教育观,及总的大众价值体系,全面否定了新文化运动及胡在其中的历史地位。  相似文献   

建立健全促进非公有制经济发展的制度支撑体系     

李太淼  张文 《黄河科技大学学报》2007,9(5):77-80

非公有制经济是我国社会主义市场经济的重要组成部分。要谋求中国经济的快速发展,必须在坚持公有制为主体的前提下大力发展非公有制经济,这已成为全党全国人民的共识;而要更好更快地发展非公有制经济,必须建立健全促进非公有制经济发展的制度和政策支撑体系,改进政府管理和服务。  相似文献