Advances in researches on the immune dysregulation and therapy of severe acute pancreatitis     

Xi-ping Zhang  Han-qing Chen  Fang Liu  Jie Zhang 《Journal of Zhejiang University. Science. B》2009,10(7):493-498

During the development and progression of severe acute pancreatitis (SAP), conspicuous immune dysregulation develops, which is mainly manifested as excessive immune response in the early stage and immunosuppression in the late stage.This process involves complex changes in a variety of immune molecules and cells, such as cytokines, complements, lymphocytes,and leukocytes. With the gradual deepening of studies on the development and progression of SAP, the role of immune dysregulation in the pathogenesis of SAP has attracted more and more attention. In this article, we review the advances in research on the immune dysregulation in SAP and the immunotherapy of this disease through exploring the formation of excessive immune response and immune suppression as well as their mutual transformation.  相似文献   

基于高校篮球训练中学生指关节损伤的调查及应对策略     

刘睿 《中国科教创新导刊》2009,(7):212-213

高校篮球课中学生的手指关节在训练中极容易发生损伤,作者运用问卷调查法、文献资料法、数据分析法、逻辑分析法,对跨省两高校学生在篮球技术课学习过程中手指关节急性损伤的成因和对策进行了分析,最后探求出了一些避免手指关节急性损伤的具体措施,旨为师生提供参考。  相似文献   

Salivary and plasma cortisol and testosterone responses to interval and tempo runs and a bodyweight-only circuit session in endurance-trained men     

Amy Vivien Tanner  Birthe Vejby Nielsen  Judith Allgrove 《Journal of sports sciences》2013,31(7):680-689

Abstract

The aim of this study was to examine the acute response to plasma and salivary cortisol and testosterone to three training protocols. Ten trained endurance athletes participated in three experimental trials, such as interval training (INT), tempo run (TEMP) and bodyweight-only circuit training (CIR), on separate days. Blood and saliva samples were collected pre- and 0, 15, 30 and 60 min post-exercise. Peak post-exercise salivary cortisol was higher than pre-exercise in all trials (P < 0.01). After INT, salivary cortisol remained elevated above pre-exercise than 60 min post-exercise. Salivary testosterone also increased post-exercise in all trials (P < 0.05). Plasma and salivary cortisol were correlated between individuals (r = 0.81, 0.73–0.88) and within individuals (r = 0.81, 0.73–0.87) (P < 0.01). Plasma and salivary testosterone was also correlated between (r = 0.57, 0.43–0.69) and within individuals (r = 0.60, 0.45–0.72), (P < 0.01). Peak cortisol and testosterone levels occurred simultaneously in plasma and saliva, but timing of post-exercise hormone peaks differed between trials and individuals. Further investigation is required to identify the mechanisms eliciting an increase in hormones in response to CIR. Furthermore, saliva is a valid alternative sampling technique for measurement of cortisol, although the complex, individual and situation dependent nature of the hormone response to acute exercise should be considered.  相似文献   

镉对中华蟾蜍蝌蚪毒性的研究   总被引：1，自引：0，他引：1  

张洪  岳兴建  王英 《内江师范学院学报》2006,21(6):58-60

用质量浓度为0.005mg·L-1、0.025mg·L-1、0.050mg·L-1、0.500mg·L-1、1.000mg·L-1、1.350mg·L-1、1.800mg·L-1的镉(Cd2 )和1个对照组(蒸馏水)进行中华蟾蜍蝌蚪的急性毒性试验,观察并记录蝌蚪的活动及反应。结果表明:Cd2 处理蝌蚪12h、24h、48h的LC50分别为1.633mg·L-1、1.202mg·L-1、1.089mg·L-1;在同一时间内随着Cd2 浓度的升高,蝌蚪的死亡率逐渐升高,而在同一Cd2 浓度下随时间的延长蝌蚪死亡率也逐渐升高;显示了在鱼病防治中镉(Cd2 )对蟾蜍蝌蚪有一定的危害。  相似文献   

Study progress in therapeutic effects of traditional Chinese medicine monomer in severe acute pancreatitis   总被引：8，自引：0，他引：8  

ZHANG Xi-ping  LIU Da-ren  SHI Yan 《Journal of Zhejiang University. Science. B》2007,8(2):147-152

INTRODUCTION Severe acute pancreatitis (SAP) is one of the three main acute abdominal problems always ac-companied by multiple-system and multiple-organ impaired function or failure. Its onset and develop-ment are characterized by rapid changes, complicated illness state and difficult treatment. With the con-tinuous development of the traditional Chinese medicine industry in recent years, it is proved that traditional Chinese medicine (TCM) monomers monomers have a marked effect for …  相似文献   

Understanding reforms,school reactions to major changes: the case of Israel     

Khalid Arar  Emanuel Tamir  Jamal Abu-Hussain 《Journal of educational administration and history》2019,51(4):402-418

ABSTRACT

Two major education system reforms were introduced by Israel’s government in collaboration with the teachers’ unions. These reforms redefine principals’ and teachers’ roles, increasing teachers’ work hours, and the scope of their work. School principals absent from the reform negotiations, are expected to apply the reform, although their work conditions were harmed. This research examines how principals cope with those reforms, and why they sometimes apply them in ways that seem to contradict their interests? Semi-structured interviews with 30 school principals, and 10 schoolteachers, indicated that the reforms have encumbered school principals’ complex tasks. They have little time or ability to thoroughly apply the reforms, responding to multiple stakeholders, political pressures, the exam regime, human resource management, etc. They often ignore policy directives, delegating authority to others, refrain from using certain resources provided by the reforms and allow internal forces to lead, while remaining uninvolved. Conclusions are presented.  相似文献   

一堂实践教学观摩课的设计与探索——以“急性左心衰病人的抢救护理”为例     

金莉 《辽宁高职学报》2012,14(9):86-88

本次实践教学观摩课以"急性左心衰病人的抢救护理"为载体,通过确定教学目标、重点难点,进行学生能力分析,进行合理的教学设计,教学过程严格地执行,以解决学生在临床实践中遇到的问题———怎样将多项护理操作综合应用于抢救护理中;对比分析课堂所讲标准操作与临床实践是否存在不同。  相似文献   

四川北部山区尖音和入声的新老差异     

张俊之 《内江师范学院学报》2012,27(11):77-78,81

四川北部山区方言的语音分尖团,同时也有一些入声的痕迹。随着语音的变化,已经出现了老派和新派的分别。  相似文献   

‘Time is not enough.’ Workload in higher education: a student perspective     

Eva Kyndt  Inneke Berghmans  Filip Dochy  Lydwin Bulckens 《高等教育研究与发展》2014,33(4):684-698

Students' workload has been recognised as a major factor in the teaching and learning environment. This paper starts by structuring the different conceptualisations of workload described in the scientific literature. Besides the traditional distinction between objective and subjective or perceived workload, a distinction between conceptualisations focusing on the perception of quantitative and qualitative aspects of workload comes to the fore. This qualitative study investigates what workload means for students in higher education. Forty Civil Engineering and Educational Sciences Master's students were interviewed. The results show that ‘having time’ is a precondition for experiencing a manageable workload. When this precondition is fulfilled, the interest of a student and the ability to plan and set priorities play an important role in the perception of workload. Finally, the results show that several aspects of the learning environment can influence this interest and the perception of workload.  相似文献   

美国高校教师工作量和业绩数据的分析与思考     

秦石乔  王省书  胡春生  战德军 《高等理科教育》2014,(3):59-63,74

文章依据美国NSOPF-93报告中工作量和研究业绩的调查统计数据,对美国全职教师的工作量和研究业绩进行了较为深入的分析与思考,对了解美国高校教师的平均工作精力投入、敬业精神和业绩水平具有重要的参考价值。同时,通过对工作量与研究业绩、业绩各要素之间数量关系的研究,得到了教学计划学时与教学准备、教学工作量与研究工作量、研究业绩(如学术论文)与教学计划学时之间的关系,对均衡教学与科研的关系具有参考性,对推进教师业绩的定量评价具有重要意义。  相似文献