右归饮对递增负荷运动大鼠睾酮和物质代谢的影响   总被引：1，自引：0，他引：1  

武玉元  常波 《天津体育学院学报》2006,21(2):132-134

目的：探讨长期大运动量训练对血睾酮和物质代谢以及补肾中药复方右归饮对其影响。方法：30只雄性SD大鼠，随机平均分为3组，分别为对照组（C）、训练组（T）和服药组（M，补肾法），进行8周递增负荷游泳。采用放免法和分光光度法观察8周递增负荷游泳和补肾中药复方对睾酮及肌糖元、肝糖元、血红蛋白和尿素氮的影响。结果：与对照组相比。训练后肌糖元和肝糖元的含量增加（P〉0．05；P〈0．05），血红蛋白降低而尿素氮升高（P〈0．01；P〈0．05）；训练组血睾酮较对照组显著降低（P〈0．05）。而补肾中药复方组（M组）能显著提高血睾酮水平（P〈0．05）。并可提高肌糖元和肝糖元的含量（P如＜0．05；P〈0.05）。结果提示，长时间大运动量训练可引起下丘脑-垂体-性腺轴产生抑制，造成运动性低血睾酮。负反馈调节作用受到不同程度的抑制，导致机体运动能力下降，恢复过程延长；而采用补肾中药复方可改善运动性低血睾酮，减缓对HPG轴负反馈的抑制作用，可以改善HPG轴的功能，增加肌糖元和肝糖元的含量，有利于大运动量训练后机体的恢复。  相似文献   

核糖对大强度耐力训练大鼠血清酶活性和血清尿素、血糖、肌肝糖原含量的影响   总被引：1，自引：0，他引：1  

熊正英  曲洪刚  刘海斌 《天津体育学院学报》2006,21(5):420-422

目的：探讨核糖对大强度耐力训练大鼠血清生化指标影响的机理．为核糖作为运动补剂提供试验依据。方法：选取24只大鼠．随机分为安静组、训练组和核糖加药组，训练组与训练加药组参照洪平等的训练模型进行3周的训练，最后一次训练进行一次性力竭运动，力竭后取血并进行样本处理。内容：利用ACE全自动生化分析仪，通过测定与运动训练相关的血清酶，血清尿素（BU）、血糖（Glu）浓度和肌肝糖原含量，研究了核糖对重要脏器的保护作用以及对糖、蛋白质代谢、大鼠跑台至力竭时间的影响。结论：核糖可保护重要器官免受运动的损伤；可促进运动中糖异生作用．有利于维持运动过程中血糖水平的稳定：可明显延缓大鼠运动疲劳的发生，使大鼠运动能力明显提高。  相似文献   

Dose requirements of continuous infusion of rocuronium and atracurium throughout orthotopic liver transplantation in humans     

Weng Xiao-chuan  Zhou Liang  Fu Yin-yan  Zhu Sheng-mei  He Hui-liang  Wu Jian 《浙江大学学报(A卷英文版)》2005,6(9):869-872

Objective: To compare the dose requirements of continuous infusion of rocuronium and atracurium throughout orthotopic liver transplantation (OLT) in humans. Methods: Twenty male patients undergoing liver transplantation were randomly assigned to two comparable groups of 10 patients each to receive a continuous infusion of rocuronium or atracurium under intravenous balanced anesthesia. The response of adductor pollicis to train-of-four (TOF) stimulation of unlar nerve was monitored. The infusion rates of rocuronium and atracurium were adjusted to maintain T1/Tc ratio of 2%–10%. The total dose of each drug given during each of the three phases of OLT was recorded. Results: Rocuronium requirement, which were (0.468±0.167) mg/(kg·h) during the paleohepatic phase, decreased significantly during the anhepatic phase to (0.303±0.134) mg/(kg·h) and returned to the initial values at the neohepatic period ((0.429±0.130) mg/(kg·h)); whereas atracuruim requirements remained unchanged during orthotopic liver transplantation. Conclusions: This study showed that the exclusion of the liver from the circulation results in the significantly reduced requirement of rocuronium while the requirement of atracurium was not changed, which suggests that the liver is of major importance in the clearance of rocuronium. A continuous infusion of atracurium with constant rate can provide stable neuromuscular blockade during the three stages of OLT.  相似文献   

血清总胆汁酸测定应列入常规肝功     

王锡军  李越等 《鸡西大学学报》2002,2(2):76-77

目的：探讨血清总胆汁酸测定在肝病各组中的阳性率，提示总胆汁酸测定应列为肝功能检查项目。方法：东瓯公司总胆汁酸试剂盒，用奥林巴斯AU640自动生化分析仪，双酶双波长测定。结果：总胆汁酸在下列各组肝病：急性肝炎、慢性活动性肝炎、慢性迁延性肝炎、肝硬化和肝癌的阳性率依次为100％、92％、15％、100％和100％，与同时测定ALT对比，其阳性率依次为100％、64％、27％、21％和36％。结论：总胆汁酸（TBA）是一项高敏感性肝功试验项目，应列为常规开展。  相似文献   

Effect of streptozotocin-induced diabetes on oxidative energy metabolism in rat liver mitochondria—A comparative study of early and late effects     

Jagannath G. Satav  Surendra S. Katyare 《Indian journal of clinical biochemistry : IJCB》2004,19(2):23-31

The reports in the literature on effects of diabetes on mitochondrial energy-linked functions are conflicting. Hence we carried out systematic studies to evaluate the effects at the early and the late stages of the disease using STZ-diabetic rat as a model. At the end of one week, after induction of diabetes, respiration rates with glutamate and succinate as the substrates increased; respiration rates with other substrates e.g. β-hydroxybutyrate, pyruvate + malate and ascorbate + TMPD were not affected despite substantial decrease in the β-hydroxybutyrate dehydrogenase activity and cytochrome b and c+c₁ contents. Insulin treatment brought about increase in the cytochrome contents beyond control values. The ATPase activity was generally low in the diabetic animals and was not restored by insulin treatment. At the end of one month, the respiratory activities with all the substrates were generally low. Insulin treatment either restored or stimulated the respiration rates beyond control values. The content of cytochromes was differentially affected in the diabetic animals, but insulin treatment caused significant increase beyond control levels. The pattern for ATPase activity was similar to the early effects. At both the stages i.e. early and late stages of diabetes the mitochondria were tightly coupled. The ADP/O ratios were in normal expected ranges and the respiratory control ratios were comparable with the control groups. Insulin treatment resulted in apparent restoration of respiratory activity. However, the effects on the cytochromes and dehydrogenases activities were differential. Taken together the two observations would suggest that the mitochondria were not re-instated to normality despite apparent restoration of respiratory function.  相似文献   

白饭树水提物对实验性肝损伤的保护作用     

许实波  王正濂  赵金华 《中山大学学报论丛》1994,(6)

白饭树(Flugea virose(Roxb ex willd) Baill [F, mierocarna Bl.])水提物对CCl_4造成的小鼠、大鼠急性肝损伤具有明显的保护作用,可使中毒鼠血清中GPT,GOT,ALP,LDH等酶的含量显著下降或趋于正常;对CCl_4所致肝脏脂质过氧化作用具明显的缓解作用,并提高CCl_4损伤肝的解毒能力.  相似文献   

斑节对虾和日本对虾肝胰腺脂肪成份和含量及其与斑节对虾杆状病毒的关系     

何建国  余南  翁少萍  江静波 《中山大学学报论丛》1996,(Z1)

体长10～12cm养殖健康斑节对虾肝胰腺含水量71．06％，干重样品脂肪含量34．28％，湿重样品脂肪含量9．60％；班节对虾杆状病毒（MBV）感染严重的班节对虾肝胰腺含水量较健康班节对虾少，干重样品脂肪含量和湿重样品脂肪含量明显高，二者比较，3项指标均具显著位差异；MBV轻度感染斑书对虾肝胰腺含水量和脂肪含量与健康斑节对虾相近，无显著性差异，养殖健康斑节对虾肝胰腺饱和脂肪酸以棕榈酸为主，不饱和脂肪酸以十八碳和二十二碳脂肪酸为主；必需脂肪酸亚油酸达21．72％，体长16～18cm日本对虾肝胰腺饱和脂肪酸以棕榈酸为主，不饱和脂肪酸中油酸、花生烯酸和二十二碳烯酸（C22：1）含量较高，亚油酸和亚麻酸含量较少，二十二碳六烯酸含量达9．91％．  相似文献   

人工肝血浆置换术中配合及护理     

田兔红  朱春梅  冯月英 《泰州职业技术学院学报》2005,5(6):47-49

目的探索重型肝炎病人血浆置换过程中的护理配合及其临床意义.方法用日本生产的Plasauto iQ系统对114例重型肝炎患者共进行182次血浆置换,每次置换血浆3-4升.通过护理方面的术前准备、术中配合,确保了人工肝血浆置换术的顺利进行.  相似文献   

白芥子中脂肪酸成分的分析   总被引：3，自引：0，他引：3  

史丽颖  吴海歌  姚子昂  冯宝民  王永奇 《大连大学学报》2003,24(4):98-99,101

[目的]确定白芥子中脂肪酸成分及含量。[方法]采用气相色谱-质谱联用法分析白芥子中脂肪酸的组成及含量。[结果]检测出7个化合物,6种脂肪酸和1种烷烃。[结论]确定了白芥子中脂肪酸的组成及相对百分含量。  相似文献   

肝移植后肝功能异常的诊断及内科处理     

窦晓光  丁阳 《大连大学学报》2006,27(4):16-18,26

已度过围手术期的肝移植患者,肝功能再次异常的原因主要包括原发病的复发,特别是乙型和丙型肝炎的复发、新病毒感染,特别是巨细胞病毒的感染、慢性排斥反应、排斥药物中毒所致肝损害等.临床诊断除常规检测肝功能外,主要依靠病毒学检测及病理诊断.内科治疗方法包括手术前的抗病毒治疗、预防呼吸道病毒感染、定期检测抗排斥药物的浓度、及时更换抗排斥药物等.  相似文献