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Obesity is one of the most important health problems, which many people suffer from it. As a chronic disease, it is a precipitating
factor for many medical conditions like hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, sleep apnea
syndrome and some malignancies (breast, uterus, prostate and colon carcinoma). With attention to this fact that obesity is
an independent risk factor associated with significant increase in morbidity and mortality, treatment of overweight individuals
is very important. One of the medications for short-term weight loss is fluoxetin. In this clinical trial study, fluoxetin
effect on weight loss induction during 8 weeks was investigated. 201 cases with BMI between 25–42 were selected randomly (113
female and 88 male) and all received fluoxetine (40 mg daily) for 8 weeks. Measurement was carried out after the 4th and 8th week of administration and 4 weeks after end of treatment. Management of 9 cases (4 due to weight gain and 5 due to headache)
were discontinued after 4 weeks of treatment. Data assessments were performed using t-test and SPSS program. Mean body weight
at first visit was 89.32±13.30kg. At the 4th, 8th week of treatment and 4 weeks after study, the mean body weight of cases reached 86.09±13.27 (p=0.00), 82.69±11.31 (p=0.00)
and 81.97±13.26 (p=0.00) respectively. Mean BMI at first visit was 34.90±5.20kg/m2. At 4th, 8th weeks of treatment it was 33.72±5.20kg/m2 and 32.40±5.18kg/m2 respectively. Mean weight loss at 4th and 8th weeks of treatment was 3.24kg and 6.67kg respectively without any weight gain at the end of the 4th week after discontinuation of the drug. Fluoxetine is an effective, well-tolerated and relatively safe drug for short-term
treatment of obesity. 相似文献
73.
佘涛 《广州体育学院学报》2015,35(3):35-38
以城市流动儿童为研究对象,分析流动儿童超重及肥胖的影响因素.运用文献资料法、测试法和数理统计法等对四川省8所公立学校7~ 12岁共2431名学生从身高、体重、BMI,并调查相应的社会经济因素等指标进行动态观察、对比和分析,结果表明:父母不同的职业对儿童的超重及肥胖情况有影响,父母职业为公务员、商业服务业人员的儿童超重及肥胖情况更严重,父母职业为农民的儿童超重及肥胖的情况较轻;父母不同的教育程度对儿童的超重及肥胖情况有影响,母亲教育程度较低的儿童超重及肥胖情况更严重;不同的家庭收入对儿童的超重及肥胖情况有影响,家庭收入较低的儿童超重及肥胖情况更严重. 相似文献
74.
Das M Ghose M Borah NC Choudhury N 《Indian journal of clinical biochemistry : IJCB》2010,25(3):295-301
Till date no community based data on plasma homocysteine is available in North Eastern Region. Hence, the present study was
conducted to analyze and correlate the plasma homocysteine level with some life style factors like diet, alcohol intake, smoking
habit and body weight, in a cross-section of population. 12 h fasting samples of 970 apparently healthy, Assamese population
of both genders in the age group of 35–86 years, mostly from the urban area of Assam were tested for plasma total homocysteine
level over a period of 3 years. Out of 970 volunteers, hyperhomocysteinemia was detected in 533 (55%) individuals with a mean
value of 18.41 μmol/l. Of that hyperhomocysteinemia, 89.1% were in the range of moderately high and rest 10.9% were intermediate
high. Another finding was that males had a tendency towards greater value (mean = 20.36 μmol/l) than females (mean = 16.37 μmol/l).
It was observed that the relationship of homocysteine levels to gender and some of the life style factors were also significant. 相似文献