Reimagining Obesity     

Jaime Schultz 《Quest (Human Kinetics)》2017,69(2):236-255

This article draws on Mills’ sociological imagination (from the 1959 publication The Sociological Imagination) to consider the connections between personal trouble and social issues when it comes to the causes and consequences of obesity. These connections may be important for assuaging the “obesity bias” that pervades our discipline, particularly as it manifests in our undergraduate students and influences the ways they will act as future professionals.  相似文献   

277例高血压患者代谢特征研究   总被引：1，自引：0，他引：1  

郝彦会 《石家庄学院学报》2010,12(3):127-128

分析新诊断的肥胖高血压患者的代谢特征,为早期防治提供相关研究数据.观察了277例患者的相关生化指标及代谢异常发生状况,结果发现无代谢异常者仅占45.1%.54.9%的患者存在着脂代谢和（或）糖代谢、尿酸代谢异常.在新诊断的肥胖高血压患者中代谢紊乱十分常见.在日常医疗工作中,对于中年肥胖患者不要忽略高血压、血脂、血糖等指标的监测,以免漏诊,延误早期治疗.  相似文献   

Association between 11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms and metabolic syndrome in Bosnian population   总被引：1，自引：0，他引：1  

Dujic T  Bego T  Mlinar B  Semiz S  Malenica M  Prnjavorac B  Ostanek B  Marc J  Causevic A 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(1):76-85

Introduction:

The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of the hormonally inactive cortisone to active cortisol, thus facilitating glucocorticoid receptor activation in target tissues. Increased expression of 11β-HSD1 in adipose tissue has been associated with obesity and insulin resistance. In this study, we investigated the association of two 11β-HSD1 gene (HSD11B1) polymorphisms with the metabolic syndrome (MetS) and its characteristics in the Bosnian population.

Materials and methods:

The study included 86 participants: 43 patients diagnosed with MetS and 43 healthy controls. Subjects were genotyped for two HSD11B1 gene polymorphisms: rs846910: G>A and rs45487298: insA, by the high resolution melting curve analysis. Genotype distribution and an influence of genotypes on clinical and biochemical parameters were assessed.

Results:

There was no significant difference in the mutated allele frequencies for the two HSD11B1 gene polymorphisms between MetS patients and controls. In MetS patients, no significant associations between disease-associated traits and rs45487298: insA were found. Regarding rs846910: G>A variant, heterozygous patients (G/A) had significantly lower systolic (P = 0.017) and diastolic blood pressure (P = 0.015), lower HOMA-IR index (P = 0.011) and higher LDL-cholesterol levels (P = 0.049), compared to the wild-type homozygotes. In the control group, rs45487298: insA polymorphism was associated with lower fasting plasma insulin levels (P = 0.041), lower homeostasis model assessment insulin resistance (HOMA-IR) index (P = 0.041) and lower diastolic blood pressure (P = 0.048). Significant differences between rs846910: G>A genotypes in controls were not detected. Haplotype analysis confirmed the association of rs45487298: insA with markers of insulin resistance in the control subjects.

Conclusions:

Our results indicate that a common rs45487298: insA polymorphism in HSD11B1 gene may have a protective effect against insulin resistance.  相似文献   

Bowels control brain: gut hormones and obesity     

Gavin A. Bewick 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(3):283-297

Peptide hormones are released from the gastrointestinal tract in response to nutrients and communicate information regarding the current state of energy balance to the brain. These hormones regulate appetite, energy expenditure and glucose homeostasis. They can act either via the circulation at target peripheral tissues, by activation of the vagus nerve or by acting on key brain regions implicated in energy homeostasis such as the hypothalamus and brainstem. This review gives an overview of the main gut hormones implicated in the regulation of food intake and how some of these are being targeted to develop anti obesity treatments.  相似文献   

武汉市成年人超重、肥胖人群心肺功能特征分析     

王雅欣 《湖北体育科技》2012,31(5):566-568

了解武汉市成年人超重、肥胖人群心肺功能特征。以2010年武汉市国民体质监测数据为基础,通过计算BMI进行分组,分析20-59岁成年人超重、肥胖人群血压、肺活量及台阶指数特征。结论：1）超重或肥胖组人群的平均血压水平明显高于体重正常组人群,体重与血压具有明显的相关性,超重和肥胖人群高血压检出率明显高于体重正常人群。2）超重或肥胖组人群肺活量/体重指数明显低于体重正常组人群,肺活量/体重指数与体重呈显著性相关,但肺活量与体重无明显的相关性。3）台阶指数与体重并无明显的相关性,与年龄具有一定的相关性。  相似文献   

运动后收缩压恢复与单纯性肥胖(超重)的关系     

陈磊  施曼莉 《体育学刊》2012,(4):134-139

分析运动后收缩压恢复(PSBPR)与单纯性肥胖(超重)的关系,探索PSBPR延迟作为肥胖(超重)患者新的调控标志物的可行性。将169名志愿者按照身体质量指数(BMI)分为肥胖(超重)组(BMI≥24 kg/m2,n=91名)和正常体重组(18 kg/m2≤BMI<24 kg/m2,n=78名)。所有受试者均进行一次递增负荷功率车实验,分别测定运动前安静时、运动中以及运动后恢复期的收缩压,以运动后第3分钟的收缩压与运动后第1分钟收缩压的比值(第3分钟收缩压恢复比,rSBPR)超过1.0作为PSBPR延迟的指标。比较两组rSBPR和PSBPR延迟发生率的差别并分析肥胖指数(体脂百分比、身体质量指数(BMI)、腰围(WC)、腰臀比(WHR)、腰围身高比(WSR))与rSBPR的相关性。结果:肥胖(超重)组rSBPR(男:0.97±0.03;女:0.95±0.05)高于正常体重组(男:0.79±0.02;女:0.80±0.04)(均为P<0.01);肥胖(超重)组PSBPR延迟发生率(男:16.0%;女:23.4%)显著高于正常体重组(男:2.7%;女:4.3%)(均为P<0.01);肥胖(超重)的男性和女性发生PSBPR延迟的危险性分别是正常体重者的8.0倍和4.6倍。相关分析显示,肥胖(超重)组男性体脂百分数、BMI与rSBPR相关系数分别为0.381(P<0.01)和0.316(P<0.01),肥胖(超重)组女性WSR与rSBPR相关系数为0.402(P<0.01),正常体重组男性体脂百分数、BMI与rSBPR相关系数分别为0.436(P<0.01)和0.310(P<0.01)。结果表明:PSBPR延迟可能是肥胖(超重)患者可调控的心血管危险因素  相似文献   

肌肉因子Irisin与运动     

林文弢  鞠丽丽  吴菊花  翁锡全 《广州体育学院学报》2016,(1):87-90

Irisin是新近在骨骼肌中发现的肌肉因子,可促进白色脂肪细胞棕色化,增加能量消耗、降低体重.运动通过影响Irisin、UCP1的表达来调控脂代谢进而改善肥胖、糖尿病等代谢性疾病,但不同运动方式和运动强度对Irisin表达的影响规律并不相同.将深入探讨运动调控lrisin表达变化的作用机制,旨为防治肥胖等代谢性疾病提供新视角.  相似文献   

儿童减肥运动处方的实践研究     

张丽蓉  高庆琦 《体育成人教育学刊》2007,23(6):32-34

根据运动处方的原理对33名肥胖儿童开具减肥运动处方并进行实验研究,研究结果表明通过针对肥胖儿个体开具减肥运动处方,按照处方进行锻炼对控制肥胖儿童的体重有显著性效果,并可以显著地提高肥胖儿童的身体素质。  相似文献   

体育锻炼对肥胖儿童减肥机理的影响   总被引：2，自引：0，他引：2  

王云  张舒  藏威 《体育科技文献通报》2009,17(3):97-97,106

采用文献法对儿童肥胖产生的机理、危害及体育锻炼对肥胖儿童减肥的生理机理进行总结、论述、分析。从而找出一种因人而异的减肥方法，在身体保持健康的基础上达到减肥效果，提高身体素质。  相似文献   

运动对腹部脂肪积累及肥胖基因表达的影响   总被引：31，自引：4，他引：27  

何玉秀  白文忠  姚玉霞  丛斌 《体育科学》1998,18(4):69-72

复制了系统游泳运动减少腹部脂肪积累的大鼠模型;用Northern印记杂交测定了训练大鼠及对照大鼠ob mRNA表达量;并对运动减肥的分子生物学机制进行初步探讨。研究结果表明系统游泳运动减少腹部脂肪积累与运动所致的ob mRNA表达水平增高密切相关。  相似文献