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71.
详细介绍了自适应α-β滤波算法的基本原理和其在雷达数据处理中的应用情况,并从原理上与其他两种比较常用的滤波算法的性能优劣对比;最后通过Matlab仿真对比和量化分析,进一步分析验证了自适应α-β滤波算法的适用性和实用性。 相似文献
72.
张军 《成都体育学院学报》2016,(5):107-112
目的：探讨在减量训练过程中，不同亚型的 PI3K 影响心肌的机制。方法：72只雄性 SD大鼠随机分为：3周安静对照组（C3）和3周大运动量训练组（E3）；3天对照组（C4）和3天减量训练组（E4）；6天对照组（C5）和6天减量训练组（E5）；2周对照组（C6）和2周减量训练组（ E6）。3周大运动量训练和2周的减量训练后取左心室肌组织，测定 PI3K p85、PI3K p110α和PI3K p110γ蛋白采用 Western blotting 方法。心肌组织形态学采用 HE 染色在光镜下观察。结果：3周大运动量训练和2周减量训练后，心肌组织形态没有显著变化，未发现心肌组织损伤。6天减量训练后，心肌 PI3K p110α蛋白表达显著增加（P ＜0.05）。2周减量训练后，心肌 PI3K p110α／ PI3K p85显著增加（P ＜0.05）。3周大运动量训练和减量训练后，心肌 PI3K p110γ蛋白表达没有显著变化（P ＞0.05）。结论：本研究制定的运动训练和减量训练方案未造成心肌损伤。减量训练通过不同亚型的PI3K影响心肌。 相似文献
73.
目的:研究低氧和低氧训练对AMPKα2转基因小鼠骨骼肌CPT-1的mRNA和蛋白表达水平的影响,进而探讨低氧和低氧训练中AMPKα2调节脂肪酸氧化过程的可能机制。方法:健康两月龄C57BL/6J品系的野生小鼠和AMPKα2转基因小鼠,分别分为常氧安静组、低氧安静组和低氧训练组,共六组,每组10只。低氧组小鼠持续暴露于低氧房中(模拟海拔4000m高度,氧浓度12.3%),其中低氧训练组小鼠还要在此低氧房中进行跑台运动,12m/min,每天1h,持续2周。测定股四头肌AMPKα2蛋白水平以及CPT-1的mRNA和蛋白表达情况。结果:2周的低氧和低氧训练对AMPKα2的蛋白表达没有显著的影响;低氧和低氧训练均显著提高了CPT-1的mRNA表达(P<0.05);低氧对野生和AMPKα2转基因小鼠CPT-1的作用无差异;低氧训练组中,AMPKα2转基因小鼠的CPT-1 mRNA表达显著高于野生小鼠(P<0.05),与低氧安静组相比,低氧训练使转基因小鼠的CPT-1蛋白表达产生了显著增加(P<0.05),但是野生小鼠并无显著变化。结论:AMPKα2参与调节了低氧训练中骨骼肌CPT-1的表达水平,促进脂肪酸的氧化过程。 相似文献
74.
张挺 《广东轻工职业技术学院学报》2014,13(3):1-4
建立热加工食品中α-乳球蛋白的双抗夹心酶联免疫检测检测方法。以热处理的α-乳白蛋白为抗原,制备抗α-乳白蛋白的高特异性单克隆抗体,并将以此蛋白作为包被抗体,构建双抗夹心ELISA方法。本方法标准曲线的IC50为360 ng/mL,方法的灵敏度为10 ng/mL。以尿素作为提取液可以大大提高热加工食品中α-乳白蛋白的提取率,添加回收率在76%~89%之间,相对标准偏差小于15%。该方法能准确地识别热加工的奶制品,避免了传统免疫方法在热加工奶制品检测上的假阴性。 相似文献
75.
在复Cn空间的单位球Bn上已经有了星形映照、螺形映照的3个扩充子类：α次殆β型螺形映射、α次β型螺形映射、α次强β型螺形映射,但这3个子类存在支持不够充足。以复分析和泛函分析为工具,在Reinhardt域Ωp1…pn上给出了这3种子类的一种构造方法,该结论对单位球Bn同样成立。 相似文献
76.
赵俊丽 《南京晓庄学院学报》2011,(6):69-72
该实验主要研究球毛壳菌素F对聚肌苷酸胞苷酸Poly（I：C）诱导的小鼠巨噬细胞系RAW264．7 TNF-α表达水平的影响．采用不同浓度的Poly（I：C）（50μg·mL-1、100μg·mL-1和200μg·mL-1）和球毛壳菌素F（2μg·mL-1）对RAW264．7进行处理,运用流式细胞术检测细胞内TNF-α的表达水平．结果表明,各浓度的Poly（I：C）与对照组相比均能极显著提高RAW264．7的TNF-α水平（P〈0．001）,并且具有浓度依赖性;球毛壳菌素F能够极显著地降低Poly（I：C）诱导的细胞TNF．O／水平（P〈0．01）．结论,球毛壳菌素F可能是通过降低炎症因子TNF-α的分泌而达到抗炎作用的． 相似文献
77.
Xuya Shang Zongyu Li Xuecheng Cao Chen Xie Mingyong Gu Pei Chen 《Journal of sports sciences》2015,33(17):1775-1779
Ankle sprains are one of the most severe musculoskeletal soft tissue injuries during physical activity. Although many risk factors have been offered, it is unclear why some individuals develop noncontact ankle sprains when participating in comparable levels of physical exertion under identical environmental conditions and others do not. The ACTN3 gene that encodes the α-actinin-3 protein, which is, only expressed in the Z line of fast glycolytic muscle fibres was found to associate with power/strength performance. The aim of this study was therefore to investigate whether the ACTN3 gene polymorphism is associated with noncontact acute ankle sprains. One hundred and forty-two participants with clinically diagnosed noncontact acute ankle sprains as well as 280 physically active controls participants without any history of ankle sprains were included in this case–control genetic association study. The RR genotype (odds ratio (OR) = 0.56; 95% confidence interval (CI), 0.32–0.65, P = 0.011) and R allele (OR = 0.64; 95% CI, 0.37–0.68, P = 0.002) of the ACTN3 were significantly low-represented in the acute ankle sprains group compared with the control group. The ACTN3 R577X is associated with acute ankle sprains in Chinese participants in this study. This is the first study to suggest that an individual with a RR genotype is at a decreased risk of acute ankle sprains. 相似文献
78.
AbstractInterest in Vitamin D has risen considerably recently with many athletes now advised to take daily vitamin D supplements. The reason for this interest is partly not only attributed to the resurgence of the Vitamin D-deficient disease rickets but also due to the discovery of a Vitamin D receptor in many tissues suggesting a more global role for Vitamin D than previously considered. Unlike the other vitamins that are obtained through the diet, Vitamin D is unique since endogenous synthesis following ultraviolet B (UVB) exposure is the predominant route of entry into systemic circulation. Moreover, Vitamin D could be better classed as a seco-steroid, given that its structure is similar to that of a steroid, and its production is derived from a cholesterol precursor (7-dehydrocholesteol) in the skin. The classification of Vitamin D status is currently subject to considerable debate with many authors opposing governing body recommendations. Regardless of the suggested optimal concentration, there is now growing evidence to suggest that many athletes are in fact Vitamin D deficient, especially in the winter months largely as a consequence of inadequate sun exposure, combined with poor dietary practices, although the consequences of such deficiencies are still unclear in athletic populations. Impaired muscle function and reduced regenerative capacity, impaired immune function, poor bone health and even impaired cardiovascular function have all been associated with low Vitamin D in athletes, however, to date, the majority of studies on Vitamin D have described associations and much more research is now needed examining causation. 相似文献
79.
目的:研究耐力性跑台运动对AMPKα2 3种不同基因型鼠骨骼肌p38、pp38和P-MEF2A蛋白表达的影响,以探讨运动激活MEF2的具体机制。方法:AMPKα2 3种不同基因型鼠各20只,分别分成安静对照组和耐力训练组,每组10只。安静组小鼠不施加任何运动负荷,耐力训练组小鼠进行速度为12m/min,每天1h,每周6天,持续4周的跑台运动。Western blot法测定骨骼肌p38、pp38和核内P-MEF2A蛋白表达。结果:1)4周耐力训练后,AMPKα2 3种基因型鼠pp38蛋白表达均显著提高,并且AMPKα2转基因鼠与野生鼠相比,p38和pp38蛋白表达明显增加,而AMPKα2敲除鼠pp38表达虽然低于野生鼠,但没有显著性差异;2)耐力训练组与安静组相比,AMPKα2 3种基因型鼠骨骼肌核内P-MEF2A蛋白表达均显著增加,并且AMPKα2转基因鼠与野生鼠相比,核内P-MEF2A表达显著增加,而AMPKα2敲除鼠P-MEF2A与野生鼠相比没有显著性差异;3)42只小鼠骨骼肌内pp38与核内P-MEF2A表达量呈显著正相关(R=0.69,P<0.05)。结论:4周耐力训练对AMPKα2 3种不同基因型鼠骨骼肌内p38蛋白表达影响不大,但可以显著促进p38和MEF2A的激活。AMPKα2可能不是惟一激活p38和MEF2A的途径,耐力训练可能通过pp38激活MEF2A。 相似文献
80.
AMPKα2基因多态性作为中国北方汉族人群心脏耐力训练敏感性分子标记的可行性研究 总被引：1，自引：0，他引：1
目的:研究腺苷酸激活的蛋激酶α2亚基(AMPKα2)基因区的7个标签单核苷酸多态性位点(SNP)及其组成的单体型与有氧耐力训练前后心脏结构和功能敏感性指标变化之间的相关性,探讨其作为有氧耐力训练敏感性分子标记的可行性。方法:对102名中国北方汉族青年进行为期18周的有氧耐力训练,测定训练前后安静时、不同负荷状态下(50 W、100 W、150 W)以及恢复期的心脏结构和功能相关指标。采用MALDI-TOF MS方法解析受试者基因组DNA多态位点基因型,分析训练前后相关指标的变化与基因型之间的关联性。结果:1)rs1418442、rs11206889以及部分单体型与心脏结构指标室间隔舒张末厚度(IVSD)和左心室质量指数(LVMI)的训练敏感性相关联;2)部分单体型与心脏功能指标150 W负荷下每搏输出量指数(SVI)的训练敏感性相关联。结论:AMPKα2基因的部分基因型或单体型可以作为中国北方汉族人群心脏对耐力训练敏感的分子标记。 相似文献