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A mutual information-based non-rigid medical image registration algorithm is presented. An approximate function of Hanning windowed sinc is used as kernel function of partial volume (PV) interpolation to estimate the joint histogram, which is the key to calculating the mutual information. And a new method is proposed to compute the gradient of mutual information with respect to the model parameters. The transformation of object is modeled by a free-form deformation (FFD) based on B-splines. The experiments on 3D synthetic and real image data show that the algorithm can converge at the global optimum and restrain the emergency of local extreme.  相似文献   
2.
Probability density function (PDF) method is proposed for analysing the structure of the reconstructed attractor in computing the correlation dimensions of RR intervals of ten normal old men. PDF contains important information about the spatial distribution of the phase points in the reconstructed attractor. To the best of our knowledge, it is the first time that the PDF method is put forward for the analysis of the reconstructed attractor structure. Numerical simulations demonstrate that the cardiac systems of healthy old men are about 6 - 6.5 dimensional complex dynamical systems. It is found that PDF is not symmetrically distributed when time delay is small, while PDF satisfies Gaussian distribution when time delay is big enough. A cluster effect mechanism is presented to explain this phenomenon. By studying the shape of PDFs, that the roles played by time delay are more important than embedding dimension in the reconstruction is clearly indicated. Results have demonstrated that the PDF method represents a promising numerical approach for the observation of the reconstructed attractor structure and may provide more information and new diagnostic potential of the analyzed cardiac system.  相似文献   
3.
结合几位专家多年从事科学研究和培养人才的经历,探讨了教育部新近推出的“2011计划”(高等学校创新能力提升计划)的深刻内涵.认为,协同创新,需要有健全的科学研究队伍体系;协同创新,需要有广阔的国际合作视野;协同创新,需要有人才、学科、科研三位一体的团队和人才梯队.  相似文献   
4.
基于两步几何主动轮廓的快速图像分割   总被引:2,自引:0,他引:2  
A fast two-stage geometric active contour algorithm for image segmentation is developed. First, the Eikonal equation problem is quickly solved using an improved fast sweeping method, and a criterion of local minimum of area gradient (LMAG) is presented to extract the optimal arrival time. Then, the final time function is passed as an initial state to an area and length minimizing flow model, which adjusts the interface more accurately and prevents it from leaking. For object with complete and salient edge, using the first stage only is able to obtain an ideal result, and this results in a time complexity of O(M), where M is the number of points in each coordinate direction. Both stages are needed for convoluted shapes, but the computation cost can be drastically reduced. Efficiency of the algorithm is verified in segmentation experiments of real images with different feature.  相似文献   
5.
Volume rendering of 3D data sets composed of sequential 2D medical images has become an important branch in image processing and computer graphics.To help physicians fully understand deep-seated human organs and focuses(e.g.a tumour)as 3D structures.in this paper,we present a modified volume rendering algorithm to render volumetric data,Using this method.the projection images of structures of interest from different viewing directions can be obtained satisfactorily.By rotating the light source and the observer eyepoint,this method avoids rotates the whole volumetric data in main memory and thus reduces computational complexity and rendering time.Experiments on CT images suggest that the proposed method is useful and efficient for rendering 3D data sets.  相似文献   
6.
The growth patterns of mammary fat pads and glandular tissues inside the fat pads may be related with the risk factors of breast cancer.Quantitative measurements of this relationship are available after segmentation of mammary pads and glandular tissues.Rat fat pads may lose continuity along image sequences or adjoin similar intensity areas like epidermis and subcutaneous regions.A new approach for automatic tracing and segmentation of fat pads in magnetic resonance imaging (MRI) image sequences is presented,which does not require that the number of pads be constant or the spatial location of pads be adjacent among image slices.First,each image is decomposed into cartoon image and texture image based on cartoon-texture model.They will be used as smooth image and feature image for segmentation and for targeting pad seeds,respectively.Then,two-phase direct energy segmentation based on Chan-Vese active contour model is applied to partitioning the cartoon image into a set of regions,from which the pad boundary is traced iteratively from the pad seed.A tracing algorithm based on scanning order is proposed to accurately trace the pad boundary,which effectively removes the epidermis attached to the pad without any post processing as well as solves the problem of over-segmentation of some small holes inside the pad.The experimental results demonstrate the utility of this approach in accurate delineation of various numbers of mammary pads from several sets of MRI images.  相似文献   
7.
Probability density function (PDF) method is proposed for analysing the structure of the reconstructed attractor in computing the correlation dimensions of RR intervals of ten normal old men.PDF contains important information about the spatial distribution of the phase points in the reconstructed attractor.To the best of our knowledge, it is the first time that the PDF method is put forward for the analysis of the reconstructed attractor structure.Numerical simulations demonstrate that the cardiac systems of healthy old men are about 6-6.5 dimensional complex dynamical systems.It is found that PDF is not symmetrically distributed when time delay is small, while PDF satisfies Gaussian distribution when time delay is big enough.A cluster effect mechanism is presented to explain this phenomenon.By studying the shape of PDFs, that the roles played by time delay are more important than embedding dimension in the reconstruction is clearly indicated.Results have demonstrated that the PDF method represents a promising numerical approach for the observation of the reconstructed attractor structure and may provide more information and new diagnostic potential of the analyzed cardiac system.  相似文献   
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