Factors for consideration to achieve a contextually appropriate physical environment in Malaysian preschools     

Pearly Pei Li Lim  Azizi Bahauddin 《International Journal of Early Years Education》2019,27(4):391-408

ABSTRACT

With studies on the physical environment of preschools concentrating mostly on settings in the Western world, before establishing minimum standards of quality, developing contextually appropriate physical environment factors become pertinent in Malaysia as a universal and possibly unaffordable high-quality standard may lead to ill-informed policy decision and allocation of funds (UNESCO 2006. EFA Global Monitoring Report 2007. Strong Foundations?: Early Childhood Care and Education). As a preliminary study, this conceptual paper sets out to uncover factors for consideration to achieve a contextually appropriate physical environment. In this article, ‘preschool’ denotes establishments for children aged four to six years in diverse educational settings. This article draws from two major fields: preschool education and physical environment of preschools. After secondary analysis of data, preliminary findings critically analysed from reviews of literature through a cross-disciplinary approach indicated that factors for consideration to achieve contextual appropriate physical environment include understanding the curriculum content; learning belief and culture of learning; physical environment factors (including allowable premise for establishing preschools, spatial planning, environmental condition and interior fit out) and statutory requirements (including health and safety factors and existing guidelines). Recommendations for future direction are discussed.  相似文献   

Coinheritance of Sicilian (δβ)<Superscript>0</Superscript>-Thalassemia and Two Rare Hemoglobin Variants: A Complex Case of Hemoglobinopathy     

Hajar Eftekhari  Maryam Pilehchian Langroudi  Ali Banihashemi  Mandana Azizi  Reza Youssefi Kamangar  Haleh Akhavan-Niaki 《Indian journal of clinical biochemistry : IJCB》2018,33(2):231-234

α-Thalassemia (α-thal) is considered as the most common inherited hemoglobin disorder worldwide. The present study describes the first observation of a combination of rare α-chain variants, and β-globin gene cluster deletion. A 21-year-old woman with thalassemia trait, marked microcytosis, mild anemia, and normal range of Hb F was referred to Amirkola genetic center in the North of Iran for routine molecular test of thalassemia in the context of carrier detection and prevention of thalassemia major birth. Nucleotide sequencing revealed a novel compound heterozygosity status for two non-deletional mutations on HBA2, Hb O Indonesia (α116(GH4)Glu → Lys), and Hb Matsue–Oki (α75 (EF4) Asp → Asn), together with heterozygosity for the sicilian (δβ)⁰-thal mutation. This finding highlights the necessity of deep molecular investigation of thalassemia in regions where thalassemia is abundant, and present highly heterogeneous population.  相似文献   

A fuzzy inference system with application to player selection and team formation in multi-player sports     

Madjid Tavana  Farshad Azizi  Farzad Azizi  Majid Behzadian 《Sport Management Review》2013,16(1):97-110

The success or failure of any team lies in the skills and abilities of the players that comprise the team. The process of player selection and team formation in multi-player sports is a complex multi-criteria problem where the ultimate success is determined by how the collection of individual players forms an effective team. In general, the selection of soccer players and formation of a team are judgments made by the coaches on the basis of the best available information. Very few structured and analytical models have been developed to support coaches in this effort. We propose a two-phase framework for player selection and team formation in soccer. The first phase evaluates the alternative players with a fuzzy ranking method and selects the top performers for inclusion in the team. The second phase evaluates the alternative combinations of the selected players with a Fuzzy Inference System (FIS) and selects the best combinations for team formation. A case study is used to illustrate the performance of the proposed approach.  相似文献   

Electromagnetic field exposure as a plausible approach to enhance the proliferation and differentiation of mesenchymal stem cells in clinically relevant scenarios     

Haslinda Abdul HAMID  Vahid Hosseinpour SARMADI  Vivek PRASAD  Rajesh RAMASAMY  Azizi MISKON 《Journal of Zhejiang University. Science. B》2022,23(1):42-57

Mesenchymal stem/stromal cell(MSC)-based therapy has been regarded as one of the most revolutionary breakthroughs in the history of modern medicine owing to its myriad of immunoregulatory and regenerative properties.With the rapid progress in the fields of osteo-and musculoskeletal therapies,the demand for MSC-based treatment modalities is becoming increasingly prominent.In this endeavor,researchers around the world have devised new and innovative techniques to support the proliferation of MSCs while minimizing the loss of hallmark features of stem cells.One such example is electromagnetic field(EMF)exposure,which is an alternative approach with promising potential.In this review,we present a critical discourse on the efficiency,practicability,and limitations of some of the relevant methods,with insurmountable evidence backing the implementation of EMF as a feasible strategy for the clinically relevant expansion of MSCs.  相似文献