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Seema Bhargava Meghaa Shanta Bhargava Eishaan Kamta Bhargava LM Srivastava 《Indian journal of clinical biochemistry : IJCB》2016,31(2):148-151
Hyperhomocysteinemia (HHCY) has been demonstrated to affect cochlear microvasculature as well as cochlear epithelial cells directly, with a resultant alteration of the expression of matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitors of metalloproteinases (TIMPs). Hence, ascertaining the optimum concentration of MMPs and TIMPs in the cochlea could help to inhibit hearing loss due to HHCY by the administration of appropriate MMP inhibitors, Since infections/inflammations as well as ototoxic antibiotics have a similar mechanism of otic pathology, the cochlear damage they cause could also be similarly prevented. 相似文献
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Susan P. Bowers 《Journal of Early Childhood Teacher Education》2013,34(3):227-233
The purpose of this study was to investigate the usefulness of standardized tests (ACT, Preprofessional Skills Test) as predictors of student success in early childhood studies. Success was measured as grade point average at the time of graduation. The sample consisted of students enrolled at a four‐year public institution in the United States (N = 129). Data analysis indicated the standardized measures, including ACT and the Preprofessional Skills Test, were significantly related to success in early childhood studies. In addition, both tests, along with high school rank and student age, were useful in the prediction of grade point average at graduation, but did little to predict success during the student teaching experience. 相似文献
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This article integrates the findings in the special issue with a comprehensive review of the evidence for seven central questions about the role of naming-speed deficits in developmental reading disabilities. Cross-sectional, longitudinal, and cross-linguistic research on naming-speed processes, timing processes, and reading is presented. An evolving model of visual naming illustrates areas of difference and areas of overlap between naming speed and phonology in their underlying requirements. Work in the cognitive neurosciences is used to explore two nonexclusive hypotheses about the putative links between naming speed and reading processes and about the sources of disruption that may cause subtypes of reading disabilities predicted by the double-deficit hypothesis. Finally, the implications of the work in this special issue for diagnosis and intervention are elaborated. 相似文献
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Lisa Jane Bowers 《Open Learning》2019,34(1):6-18
ABSTRACTMachine haptics has been shown to assist and enhance human–computer interactions. Research from previous studies in the field of haptics has focused on developing a user’s sense of realism of touch when using a haptic device. This paper examines the use of haptics for education, specifically for creative online education. The paper is presented in two parts. First, a review of literature was conducted and used to aid the rationale and underpin the design of a pilot test. Second, a pilot test was designed using a single-point kinaesthetic haptic device with a haptic rendered interface, to support the assembly of a virtual design prototype. The pilot test proved to be extremely valuable in creating and developing a rich virtual environment for non-sighted and sighted participants to use. The results from the initial pilot test showed that although users were positive about their experience of using the haptic device, there were improvements to be made to the interface to enhance the user experience in the next phase of testing. 相似文献
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