基于二模复杂网络的隐性知识发现方法研究——以潜在药物靶点挖掘为例     

李东巧  陈芳  韩涛  杨艳萍  王学昭  王燕鹏  Cynthia Liu  Yingzhu Li 《图书情报工作》2020,64(21):120-129

[目的/意义] 通过构建二模复杂网络模型，揭示隐藏在海量文献中的隐性知识。[方法/过程] 通过NetworkX复杂网络工具包，依据任意两个节点的共现关系构建二模复杂网络模型；对网络模型中节点的共现关系进行加权，计算网络的拓扑信息并进行AP聚类，提取节点间的直接关系；采用AUC方法对AA、JC、加权改进的wAA和wJC等4种链路预测算法进行评价，遴选出最合适的预测算法，并对复杂网络的隐性关系进行预测分析。[结果/结论] 以潜在药物靶点挖掘为例进行的实证研究结果表明，wAA链路预测算法为最优的链路预测算法；二模复杂网络模型、指标和方法体系在美国化学文摘社数据库中的药物靶点挖掘中具有一定的有效性。下一步计划在其他数据库中或其他研究领域中进行尝试，以进一步验证该模型的通用性和有效性。  相似文献   

Erratum to: Measuring the concerns of adolescents: Developing a concise classificatory system     

Erica Frydenberg  Ramon Lewis 《The Australian Educational Researcher》1996,23(3):vi-vi

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Effects of Manipulative Instruction on Solving Area and Perimeter Problems by Students with Learning Disabilities     

Mike Cass  Dennis Cates  Michelle Smith  Cynthia Jackson 《Learning disabilities research & practice》2003,18(2):112-120

Abstract. A multiple baseline design was employed to test the effect of manipulative instruction on the perimeter and area problem‐solving performance of middle and high school students who had been diagnosed with LD in the area of mathematics. Modeling, prompting/guided practice, and independent practice in conjunction with manipulative training were employed to teach both perimeter and area problem‐solving skills. Analysis of data revealed that the students rapidly acquired the problem‐solving‐skills, maintained these skills over a two‐month period, and transferred these skills to a paper and pencil problem‐solving format. This research extends previous findings by revealing that use of concrete manipulatives promotes the long‐term maintenance of skills.  相似文献   

Good High Schools for Students with Disabilities     

Catherine Cobb Morocco  Cynthia Mata Aguilar  Karen Clay  Nancy Brigham  Naomi Zigmond 《Learning disabilities research & practice》2006,21(3):135-145

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Research,Teaching and Scholarship in an Expanding Higher Education System 1     

Lewis Elton 《Higher Education Quarterly》1992,46(3):252-268

It is argued that, basically, academics engage in three activities: teaching, research and scholarship, and that the activity of scholarship must be recognised and separately funded. The concept of scholarship is derived from its historical roots, according to which it supports both teaching and research, but is extended to support all activities in which academics engage. This makes it possible to develop an expanding system of higher education in which all academic activities are appropriately recognised and rewarded and which can operate with significantly lower unit costs than has been the case in the past. However, the need to provide funding for scholarship puts a lower bound to acceptable unit costs.  相似文献   

Non-finite loss and challenges to communication between parents and professionals     

Elizabeth Bruce  & Cynthia Schultz 《British Journal of Special Education》2002,29(1):9-13

Elizabeth Bruce PhD, a psychologist in private practice, and Cynthia Schultz PhD, honorary associate at LaTrobe University, both live and work in Australia. Their work on supporting parents who have children with special needs, however, has been published around the world. In this article Bruce and Schultz explore the notion of 'non-finite loss', defined as the ongoing sense of grief experienced by parents caring for children with severe disabilities. The authors discuss the issues that professionals need to consider when working with parents in these circumstances. The article closes with a set of recommendations for promoting more effective partnerships between parents and professionals.  相似文献   

So many filters, so little time: the development of a search filter appraisal checklist          下载免费PDF全文

Julie Glanville  Sue Bayliss  Andrew Booth  Yenal Dundar  Hasina Fernandes  Nigel David Fleeman  Louise Foster  Cynthia Fraser  Anne Fry-Smith  Su Golder  Carol Lefebvre  Caroline Miller  Suzy Paisley  Liz Payne  Alison Price    Karen Welch 《Medical Library and Historical Journal》2008,96(4):356-361

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Television, Public Opinion and the War in Iraq: The Case of Britain     

Lewis  Justin 《Int. Journal of Public Opinion Research》2004,16(3):295-310

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概说虚拟存储     

Mark Lewis 《中国传媒科技》2005,(10)

虚拟是今天存储业界的热门话题,对数据的管理就是对存储的管理。大小客户如何利用虚拟存储解决方案并通过存储软件和存储硬件自身内部的分区来最大程度地利用自身的存储基础架构呢?与此同时,客户们仍在问究竟什么是虚拟存储呢?如何实现这些技术呢?企业自身的基础架构是否适合实现存储虚拟化呢?  相似文献   

How U.S. and Chinese journalists think about plagiarism     

Norman P. Lewis  Fan Yang  Yong Zhou 《亚洲交流杂志》2018,28(5):490-507

A comparison of 1,096 professional journalists in China and the United States on attitudes toward attribution and plagiarism reveals Chinese journalists were more likely to see attribution as a practice to be embraced regardless of career longevity and culture, suggesting journalistic norms are more important than a collectivist orientation. Attribution was more likely to be embraced by those who see principles as more important than expediency, affirming research that plagiarism is hardly a monolithic concept. Overall, journalists in the two nations did not vary significantly in their attitudes toward plagiarism, despite vast differences in culture and politics as well as evidence that in some other fields China is more accepting of reusing material without attribution. The data show that among journalists, attitudes toward plagiarism are shared across national boundaries, reinforcing related research showing that a journalism culture exists and is shared at least in part across national boundaries.  相似文献