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ABSTRACT

The length of telomeres is an objective measure of biologic ageing. This study evaluated the extent minutes of walking per week are associated with leukocyte telomere length (LTL) in a random sample of 5,823 U.S. adults. The investigation was cross-sectional and data were obtained from the National Health and Nutrition Examination Survey (NHANES). LTL was measured by the quantitative polymerase chain reaction method. Walking minutes was calculated from walking frequency and duration measures. Results showed that for each year of chronological age, telomeres were 15.6 base pairs shorter (P < 0.0001). With walking minutes and LTL treated as continuous variables, the relationship was quadratic, not linear (F = 11.2, P = 0.0023). With walking time divided into three categories, adults who performed ≥ 150 minutes of walking per week had longer telomeres than those who did no regular walking, and those who did some, but less than the recommendation (F = 5.0, P = 0.0137). Regular walkers were estimated to have a biologic ageing advantage associated with 6.5–7.6 years less biologic ageing compared to non-walkers, after adjusting for covariates. Additional investigations designed to study causality and the mechanisms associated with the walking and LTL relationship are needed.  相似文献   
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The aim of this study was to determine whether gait cycle characteristics are associated with running economy in elite Kenyan runners. Fifteen elite Kenyan male runners completed two constant-speed running sets on a treadmill (12 km ·h?1 and 20 km ·h?1). VO2 and respiratory exchange ratio values were measured to calculate steady-state oxygen and energy cost of running. Gait cycle characteristics and ground contact forces were measured at each speed. Oxygen cost of running at different velocities was 192.2 ± 14.7 ml· kg?1· km?1 at 12 km· h?1 and 184.8 ± 9.9 ml· kg?1· km?1 at 20 km· h?1, which corresponded to a caloric cost of running of 0.94 ± 0.07 kcal ·kg?1·km?1 and 0.93 ± 0.07 kcal· kg?1· km?1. We found no significant correlations between oxygen and energy cost of running and biomechanical variables and ground reaction forces at either 12 or 20 km· h?1. However, ground contact times were ~10.0% shorter (very large effect) than in previously published literature in elite runners at similar speeds, alongside an 8.9% lower oxygen cost (very large effect). These results provide evidence to hypothesise that the short ground contact times may contribute to the exceptional running economy of Kenyan runners.  相似文献   
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Polyvocal approaches allow researchers and informants to interact on a more equal footing and informants’ voices to be heard in the final text. But research methods intended to empower informants also can be a source of unanticipated authorial power ‐ the power to confront informants with unsolicited self‐reflections and to textualize people's lives and words. The authors reflect on those ethical dilemmas in this article.  相似文献   
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The current study tests the influence of threatening-mediated intergroup contact on intergroup relations. A 2 (Immigration: Threat, No-threat) × 2 (Ingroup Group Exemplar: Present, Absent)?+?1 (Control Condition) experimental design was used to examine both the direct and indirect influence of news exposure on attitudes toward immigration. The moderating role of previous local news consumption was also investigated. Results indicate that exposure to a threatening news story about immigration directly affected attitudes toward immigrants’ human rights, but not attitudes toward immigration policy. News exposure also indirectly influenced both types of immigration attitudes through feelings of intergroup anxiety, particularly for heavy news consumers. The discussion highlights the implications for both intergroup threat theory and cultivation research.  相似文献   
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Mooses and colleagues suggest that running economy alone does not explain superior distance running performance in elite Kenyan runners. Whilst we agree with the multi-factorial hypothesis for Kenyan running success, we do not believe that running economy can be overlooked to the extent that it was based on this particular study. Based on the methods used and the range of athletes tested, in this response letter we question whether this study provides any basis for downplaying the influence of running economy or suggesting that other factors compensate for it to enable superior performance.  相似文献   
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