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Jeonghun Nam Justin Kok Soon Tan Bee Luan Khoo Bumseok Namgung Hwa Liang Leo Chwee Teck Lim Sangho Kim 《Biomicrofluidics》2015,9(6)
A novel microfluidic device which consists of two stages for particle focusing and separation using a viscoelastic fluid has been developed. A circular capillary tube was used for three-dimensional particle pre-alignment before the separation process, which was inserted in a polydimethylsiloxane microchannel. Particles with diameters of 5 and 10 μm were focused at the centerline in the capillary tube, and the location of particles was initialized at the first bifurcation. Then, 5 and 10 μm particles were successfully separated in the expansion region based on size-dependent lateral migration, with ∼99% separation efficiency. The proposed device was further applied to separation of MCF-7 cells from leukocytes. Based on the cell size distribution, an approximate size cutoff for separation was determined to be 16 μm. At 200 μl/min, 94% of MCF-7 cells were separated with the purity of ∼97%. According to the trypan blue exclusion assay, high viability (∼90%) could be achieved for the separated MCF-7 cells. The use of a commercially available capillary tube enables the device to be highly versatile in dealing with particles in a wide size range by using capillary tubes with different inner diameters. 相似文献
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In this paper, the quadratic minimax optimal control of linear system with input-dependent uncertainty is studied. We show that it admits a unique solution and can be approximated by a sequence of finite-dimensional minimax optimal parameter selection problems. These finite-dimensional minimax optimal parameter selection problems are further reduced to scalar optimization problems which also admit unique solutions. Thus, the original minimax optimal control problem is solved via solving a sequence of simple scalar optimization problems. Numerical experiments are presented to illustrate the developed method. 相似文献
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Melissa Ng Lee Yen Abdullah See Ching Mey Tan Kok Eng Rosly Othman Ahmad Fairuz Omar 《Journal of Research in Special Educational Needs》2013,13(4):259-271
Transition services are required by law for students with disabilities in many developed countries. In Malaysia, however, there is still no specific legislation mandating that school‐to‐work transition planning and services be provided to students with disabilities. This study investigated the state of the transition services provided by educational organisations to students with disabilities in Malaysia. A mixed method research design, which utilises both quantitative and qualitative research techniques, was employed to obtain information from 23 government organisations and NGOs involved in the education and training of students with disabilities. This study found that the organisations surveyed were aware of the lack of transition support and call attention to the importance of instituting a national policy on school‐to‐work transition services and supported employment systems for students with disabilities. The legislative and educational implications for Malaysia are discussed. 相似文献
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Science Teachers’ Perceptions: Similarities and Differences in the U.S., England,Singapore and Japan
The prospect of using internationally generated comparative data, augmented with practice patterns, to provide useful information from which countries can learn from each other, is gaining acceptance from the increasing popularity of such an approach (Stigler and Hiebert, 1999). Using the survey data from TIMSS we examine the beliefs of teachers in the U.S., England, Singapore and Japan, and find little national variation in many teachers’ perceptions of core practices in science teaching, indicating that science teachers the world over share the same common core practices. However, there is one key difference among their practices, which signals a departure in the way teachers in Japan and Singapore operate vis‐à‐vis those in the U.S. and England. This key difference is attributed to cultural differences in the U.S. and England, when compared to Japan and Singapore. 相似文献
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Toh Kok Aun Joseph P. Riley II Lourdusamy Atputhasamy R. Subramaniam 《Educational Research for Policy and Practice》2006,5(1):1-13
This paper compares and contrasts school science achievement between two top scoring nations, Japan and Singapore, on the
Third International Mathematics and Science Study (TIMSS) assessments. The first part of the study is devoted to examining
cross-national comparisons on selected background questions administered in the TIMSS survey, while the second part examines
selected educational attributes and practices that might help explain their consistently high achievement in science. Attention
to TIMSS data has chiefly focused on the achievement gap between US and other nations. This report moves beyond US deficit
comparisons to examine results and programs of high achieving nations to better inform efforts to close the gaps. 相似文献
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This paper seeks to bridge the gap between socio-material and complex adaptive systems approaches in conceptualizing the politics of transformation. Our contribution in particular is a further clarification of the relational nature of power, and the role of non-humans in transitional dynamics of complex adaptive systems. We explore and operationalize the role of non-humans and relationality in (1) agency and (2) power, and the implications thereof for processes of (3) powering, through which power relations shape resource distributions and associated macro-scale dynamics. We consider agency as an embedded and temporal capacity for reorientation. This also entails attributing agency to entangled networks of humans and non-humans. Such a capacitive conception of agency follows from our understanding that agents and structures consist of comparable ontological building blocks, both being (networks of) components in complex adaptive systems. Power we understand as a productive and relational phenomenon that emerges from interactions between components and that structures their agency. We argue that such a ‘force-field’ understanding of power enables the observation of different types of power relations. Finally, we consider six different mechanisms through which power relations can result in a (re)distribution of resources and with that, contribute to self-reproducing or transformative systemic dynamics. With this conceptualization, we hope to advance the debate on the different facets of the politics of transformation, and to help further urgently needed transitions towards a more sustainable future. 相似文献
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After introducing a differentiation model for the benefit of gifted pupils in regular schools, this article discusses some important findings of the research project “High giftedness in education”, carried out at the ISOR, the Educational Research Department at the University of Utrecht. Data from survey research indicate what special provision has been made for gifted pupils in secondary schools in the Netherlands. Further data summarize experiences with the differentiation model at two different types of secondary school. Finally, some adaptations of the differentiation model are outlined. 相似文献
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The literacy practices of many communities today show new ways of meaning making in the contemporary, technological and digital culture. A number of Malaysian adolescents belong to this culture. This pilot study reports the preliminary findings of a larger study aimed at describing the online activities of Malaysian adolescents. Fifty‐four participants from an urban secondary school in Penang took part in this study. One finding showed that the percentages of language use on the Internet were: 80.6 per cent in English, 10.6 per cent in Bahasa Malaysia and 8.8 per cent in Chinese. In addition, the study also revealed some common websites that these adolescents frequented. The findings point to the need to investigate the extent of these online literacy practices beyond school among the adolescent population in Malaysia and to look into the implications for ESL education. 相似文献