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Clark A. Chinn Susan A. Yoon Huma Hussain-Abidi Kyle Hunkar Noora F. Noushad Amanda M. Cottone Thomas Richman 《European Journal of Education》2023,58(3):407-421
An important goal of science education is promoting scientific literacy—the competence to interact with science as laypeople to solve problems and make decisions in their personal and community lives. This is made more challenging in an age of increasing science denialism. In this article, we discuss how to design learning environments for science education that can help students attain scientific literacy. We argue that science curricula should encompass lessons with two distinguishable foci. One focus engages students in understanding the reliability of science. The second focus engages students as laypeople interacting with science in the public sphere. We discuss these two curricular foci, presenting examples from our own work on designing and implementing instruction with the first focus. 相似文献
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Huma Nasrat Surajeet K. Patra Binita Goswami Anju Jain Chitra Raghunandan 《Indian journal of clinical biochemistry : IJCB》2016,31(1):104-107
Polycystic ovary syndrome (PCOS) is a common endocrinological disorder among women of the reproductive age group with long term sequelae which include diabetes mellitus, hypertension and CAD. The present study was conducted to evaluate the association of leptin—an adipokine playing an important role in carbohydrate metabolism and markers of insulin resistance among women with PCOS. Sixty diagnosed cases of PCOS as per Rotterdam criteria were enrolled in this study after informed written consent. Insulin resistance was estimated using the homeostatic model assessment-insulin resistance (HOMA-IR). HOMA-IR was calculated as the product of the fasting plasma insulin value (mU/ml) and the fasting plasma glucose value (mg/dl), divided by 405 and HOMA β was calculated as 360 × [insulin]/([glucose] − 63) % (glucose in mg/dl). Estimation of serum leptin levels was done by ELISA using leptin ELISA kit from (DRG). A positive correlation of serum leptin levels was observed with markers of insulin resistance. Multiple regression analysis with HOMA-IR as dependent variable demonstrated a statistically significant contribution of fasting insulin levels. This study highlights the role of leptin in alterations in carbohydrate metabolism in patients with PCOS. 相似文献
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研究急性低氧及力竭运动对大鼠骨骼肌肌球蛋白重链(MHC)亚型基因表达的影响。取健康SD雌性大鼠80只，随机分成4大组：常氧对照组(C)，常氧力竭组(NE)，低氧对照组(HC)和低氧力竭组(HE)。采用半定量反转录聚合酶链式反应(RT—PCR)法，测定各组骨骼肌MHCⅠ、Ⅱa、Ⅱx、Ⅱb4种亚型的mRNA基因表达。结果表明，MHC各亚型mRNA所占百分比分析显示，单纯低氧能刺激MHC亚型mRNA表达出现“由慢到快”的趋势；力竭运动则能刺激MHC mRNA表达出现“由快到慢”的趋势。关于MHC亚型转变在功能上的意义还有待进一步研究。 相似文献
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