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Brian Merrick 《Children‘s Literature in Education》1991,22(1):25-34
Brian Merrick bas made a major contribution to the development of poetry teaching for younger children in the United Kingdom during the 1980s. CLE invited bim to look back over the decade and to select a personal list of favorite collections.ForCLE he has written on Poetry in Performance (issue 35) and Charles Causley (issue 70). The latter article was expanded intoTalking with Charles Causley for the National Association for the Teaching of English (1989). NATE has also published his influentialExploring Poetry: 5–8 (1987) andExploring Poetry: 8–13 (1990). 相似文献
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Christopher R. Phaneuf Nikita Pak D. Curtis Saunders Gregory L. Holst Joav Birjiniuk Nikita Nagpal Stephen Culpepper Emily Popler Andi L. Shane Robert Jerris Craig R. Forest 《Biomicrofluidics》2015,9(4)
Amplification of multiple unique genetic targets using the polymerase chain reaction (PCR) is commonly required in molecular biology laboratories. Such reactions are typically performed either serially or by multiplex PCR. Serial reactions are time consuming, and multiplex PCR, while powerful and widely used, can be prone to amplification bias, PCR drift, and primer-primer interactions. We present a new thermocycling method, termed thermal multiplexing, in which a single heat source is uniformly distributed and selectively modulated for independent temperature control of an array of PCR reactions. Thermal multiplexing allows amplification of multiple targets simultaneously—each reaction segregated and performed at optimal conditions. We demonstrate the method using a microfluidic system consisting of an infrared laser thermocycler, a polymer microchip featuring 1 μl, oil-encapsulated reactions, and closed-loop pulse-width modulation control. Heat transfer modeling is used to characterize thermal performance limitations of the system. We validate the model and perform two reactions simultaneously with widely varying annealing temperatures (48 °C and 68 °C), demonstrating excellent amplification. In addition, to demonstrate microfluidic infrared PCR using clinical specimens, we successfully amplified and detected both influenza A and B from human nasopharyngeal swabs. Thermal multiplexing is scalable and applicable to challenges such as pathogen detection where patients presenting non-specific symptoms need to be efficiently screened across a viral or bacterial panel. 相似文献
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Rosalind Merrick 《Support for Learning》2020,35(1):101-118
There are legal, moral and practical reasons to involve pupils in planning provision for their special educational needs. We do not yet know how principles are implemented in practice. This study explored the views and experiences of 64 teachers with an interest in special educational needs through an online survey. Participants reported greater pupil involvement in everyday matters, less in conceptual aspects of planning. Effective strategies were based on good teacher-pupil relationships and school-wide systems for sharing pupil views. Participants gave examples of the impact of pupil participation on teacher insight, pupil motivation and material provision. 84 per cent indicated that they would like pupils to be more involved in decisions about their provision than they currently are. Barriers included the nature of children’s difficulties and practitioner attitudes. Listening to children is intrinsic to good teaching, yet pupils also benefit from a more formal role in provision planning. 相似文献
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Performance-Verbal IQ discrepancy scores are compared for 27 depressed and 15 nondepressed children all of whom experienced learning difficulties. Brumbach (1985) reported a significant association between depression and Performance IQ deficits for children with learning difficulties. In contrast to Brumbach's finding, no difference was observed in Performance IQ deficit between depressed and nondepressed children in the current study. Moreover, only 10% of depressed children showed such a deficit. This result differed significantly from Brumbach's findings (34%). Implications of these results are discussed within the context of nascent interest in the relationship between depression and learning disabilities. 相似文献