Early Childhood Parenting Predicts Late Childhood Brain Functional Connectivity During Emotion Perception and Reward Processing     

Daniel C. Kopala-Sibley  Marilyn Cyr  Megan C. Finsaas  Jonathan Orawe  Anna Huang  Nim Tottenham  Daniel N. Klein 《Child development》2020,91(1):110-128

Seventy-nine 3-year olds and their mothers participated in a laboratory-based task to assess maternal hostility. Mothers also reported their behavioral regulation of their child. Seven years later, functional magnetic resonance imaging data were acquired while viewing emotional faces and completing a reward processing task. Maternal hostility predicted more negative amygdala connectivity during exposure to sad relative to neutral faces with frontal and parietal regions as well as more negative left ventral striatal connectivity during monetary gain relative to loss feedback with the right posterior orbital frontal cortex and right inferior frontal gyrus. In contrast, maternal regulation predicted enhanced cingulo-frontal connectivity during monetary gain relative to loss feedback. Results suggest parenting is associated with alterations in emotion and reward processing circuitry 7–8 years later.  相似文献   

Investigations regarding the behaviour of historic glass and its surface layers towards different wavelengths applied for laser cleaning     

Farideh Fekrsanati  Stefan Klein  Jens Hildenhagen  Klaus Dickmann  Yiorgos Marakis  Aleka Manousaki  Vassilis Zafiropulos   《Journal of Cultural Heritage》2001,2(4):187

The application of lasers for the removal of superficial deposits from historic stained glass is a comparatively new field of scientific interest. Experimental studies concerning the behaviour of glass substrates and the corresponding superficial deposits towards different laser wavelengths were carried out. The experiments were performed using wavelengths of λ = 193 nm (ArF-Excimer), 308 nm (XeCl-Excimer), 355 nm (Nd:YAG third harmonic) and 1 064 nm (Nd:YAG fundamental) in comparison to λ = 248 nm (KrF-Excimer). This comparison is due to the fact that the present knowledge is based on the 248 nm wavelength. Specially prepared model glass samples representing the original fragments and samples of organic polymers (formerly used as a protective material for historic stained glasses) were used to study the effects of laser radiation and were subsequently characterised by optical microscopy.  相似文献   

Chicago medical library journal club     

Klein RS  Slowinski R 《Bulletin of the Medical Library Association》1976,64(3):320

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Metropolis redux: the unique importance of library skills in informatics.     

Samuel Bishop King  Kate MacDonald 《Journal of the Medical Library Association》2004,92(2):209-217

OBJECTIVES: The objective is to highlight the important role that librarians have in teaching within a successful medical informatics program. Librarians regularly utilize skills that, although not technology dependent, are essential to conducting computer-based research. The Metropolis analogy is used to introduce the part librarians play as informatics partners. Science fiction is a modern mythology that, beyond a technical exterior, has lasting value in its ability to reflect the human condition. The teaching of medical informatics, an intersection of technology and knowledge, is also most relevant when it transcends the operation of databases and systems. Librarians can teach students to understand, research, and utilize information beyond specific technologies. METHODS: A survey of twenty-six informatics programs was conducted during 2002, with specific emphasis on the role of the library service. RESULTS: The survey demonstrated that librarians currently do have a central role in informatics instruction, and that library-focused skills form a significant part of the curriculum in many of those programs. In addition, librarians have creative opportunities to enhance their involvement in informatics training. As a sample program in the study, the development of the informatics course at the Massachusetts College of Pharmacy and Health Sciences is included. CONCLUSIONS: Medical informatics training is a wonderful opportunity for librarians to collaborate with professionals from the sciences and other information disciplines. Librarians' unique combination of human research and technology skills provides a valuable contribution to any program.  相似文献   

‘It's The Catcher in the Rye… He said it was the kind of book you made your own': Finding Holden in Contemporary YA Literature     

Steven T. Bickmore  Kate Youngblood 《English in Education》2014,48(3):250-263

Published in 1951,The Catcher in the Rye encapsulated teenage angst. Some time ago David Belbin mused about the influence of Catcher on the proliferation and popularity of YA literature. Salinger's recent death has sparked a renewed interest in his work and more attention on Holden and his inheritors. This article discusses how five recent adolescent novels, with male protagonists, mirror Holden's adolescent paralysis. They exist in a liminal state between childhood and adulthood, attempting to understand the phonies around them. These protagonists help define the nature of the ‘lost’ adolescent in the current golden age of YA literature.  相似文献   

Academe’s House Divided     

Daniel B. Klein 《Academic Questions》2011,24(3):365-370

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Unconscious and unnoticed professional practice within an outstanding school for children and young people with complex learning difficulties and disabilities     

Richard Crombie  Lesley Sullivan  Kate Walker  Rebecca Warnock 《Support for Learning》2014,29(1):7-23

This article describes a three‐year project undertaken at Pear Tree School for children and young people with severe and multiple and profound learning difficulties. Lesley Sullivan, the school's head teacher, believed that much of the value within the work of this outstanding school went unidentified by existing approaches to planning, monitoring and evaluation. Richard Crombie, educational psychologist, was engaged to work on the project. Also involved were Kate Walker and Rebecca Warnock, deputy head teachers, as well as the whole staff, children and some parents. The project takes as its starting point that essential, but very often unnoticed and unconscious, professional practice is rooted in implicit processes learnt experientially. We set ourselves the task of finding meaningful frameworks for identifying and developing that practice. This meant close observation within and outside school coupled with feeding back to staff, and their subsequent engagement with and use of explanatory frameworks.  相似文献   

Strength,Weakness, Opportunity,Threat (SWOT) Analysis of the Adaptations to Anatomical Education in the United Kingdom and Republic of Ireland in Response to the Covid-19 Pandemic     

Georga J. Longhurst  Danya M. Stone  Kate Dulohery  Deirdre Scully  Thomas Campbell  Claire F. Smith 《Anatomical sciences education》2020,13(3):301-311

The Covid-19 pandemic has driven the fastest changes to higher education across the globe, necessitated by social distancing measures preventing face-to-face teaching. This has led to an almost immediate switch to distance learning by higher education institutions. Anatomy faces some unique challenges. Intrinsically, anatomy is a three-dimensional subject that requires a sound understanding of the relationships between structures, often achieved by the study of human cadaveric material, models, and virtual resources. This study sought to identify the approaches taken in the United Kingdom and Republic of Ireland to deliver anatomical education through online means. Data were collected from 14 different universities in the United Kingdom and Republic of Ireland and compared adopting a thematic analysis approach. Once themes were generated, they were collectively brought together using a strength, weakness, opportunity, threat (SWOT) analysis. Key themes included the opportunity to develop new online resources and the chance to engage in new academic collaborations. Academics frequently mentioned the challenge that time constrains could place on the quality and effectiveness of these resources; especially as in many cases the aim of these resources was to compensate for a lack of exposure to cadaveric exposure. Comparisons of the actions taken by multiple higher education institutions reveal the ways that academics have tried to balance this demand. Discussions will facilitate decisions being made by higher education institutions regarding adapting the curriculum and assessment methods in anatomy.  相似文献   

Perceived and experienced stigma among people living with HIV: Examining the role of prior stigmatization on reasons for and against future disclosures     

Danielle Catona  Kathryn Greene  Kate Magsamen-Conrad  Amanda Carpenter 《Journal of Applied Communication Research》2016,44(2):136-155

HIV remains a significant health concern entering the fourth decade of the epidemic [Centers for Disease Control and Prevention. 2014. HIV basics. Retrieved from http://www.cdc.gov/hiv/basics/index.html], and people living with HIV continue to grapple with stigma. This study uses Leary and Schreindorfer's [1998 Leary, M. R., &; Schreindorfer, L. S. (1998). The stigmatization of HIV and AIDS: Rubbing salt in the wound. In V. J. Derlega &; A. P. Barbee (Eds.), HIV and social interaction (pp. 12–29). Thousand Oaks, CA: Sage. [Google Scholar]. The stigmatization of HIV and AIDS: Rubbing salt in the wound. In V. J. Derlega &; A. P. Barbee (Eds.), HIV and social interaction (pp. 12 Lekas, H. M., Siegel, K., &; Schrimshaw, E. W. (2006). Continuities and discontinuities in the experiences of felt and enacted stigma among women with HIV/AIDS. Qualitative Health Research, 16, 1165–1190. doi:10.1177/1049732306292284[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]–29 Lekas, H. M., Siegel, K., &; Schrimshaw, E. W. (2006). Continuities and discontinuities in the experiences of felt and enacted stigma among women with HIV/AIDS. Qualitative Health Research, 16, 1165–1190. doi:10.1177/1049732306292284[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). Thousand Oaks, CA: Sage] conceptualization of stigma to explore prior stigmatization on reasons for and against future disclosures. We interviewed HIV+ individuals (N?=?59) and used a combination of deductive and inductive coding to analyze participants’ responses. Deductive codes consisted of four stigma characteristics (pose a threat to others’ health and safety, deviate from group standards, create negative emotional reactions in others, and failure to contribute), experiences of feeling stigmatized due to HIV status (yes or no), and the degree to which HIV stigma was a concern (major, minor, or no concern). Inductive coding identified examples of perceived and experienced stigma and stigma concerns on future disclosure decision-making. Practical implications discuss individual, institutional, and societal stigma-reduction interventions and programs.  相似文献   

Observations on the temporal correlates of reading failure     

Raymond M. Klein 《Reading and writing》2002,15(1-2):207-231

The definitions of developmental dyslexia andtemporal processing are discussed and severalconstruals of what a temporal processingdeficit might entail are illustrated. Then,using a framework developed by Farmer & Klein(1995), the proposal that a temporal processingdeficit (in vision, audition, or both) might bethe root cause of some proportion of cases ofdevelopmental dyslexia is introduced andvarious research strategies for testing thisproposal are identified. The symposium paperswhich address this general question using arange of these strategies are then criticallyreviewed. It is noted that whereas reading isa recent artifact not yet subject to any directselection pressure, its normal performancerequires the use of, and connections between,the highly evolved modules for visual patternrecognition and language. Within vision andlanguage redundant coding, which permitsperformance in the face of injuries anddegraded input, also makes it difficult todetect subtle deficits (whether temporal, ornot) unless precise tests are used. Yet suchdeficits may degrade performance on tasks (suchas reading) which require the non-copiousconnections between vision and language. Theefficacy of this pathway, I suggest, ismeasured by performance on the rapidautomatized naming (RAN) test.  相似文献