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Changes in erythrocyte membrane glycoproteins during, leukaemia were investigated in one hundred patients. Control group contained normal ones. The total protein and protein bound total carbohydrates (neutral sugars) in the glycoproteins extracted from the erythrocyte membrane showed significant reduction in total protein and protein bound total carbohydrates before radiotherapy. However, after the radiotherapy there was further reduction in total protein by 10.41% whereas there was increase in total carbohydrates by 9.98%. Qualitative analysis reveals that with the help of lectins one can pin point the sugars which appear or disappear due to leukaemia. The test could be of a diagnostic value.  相似文献   
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With the growth of social media, document sentiment classification has become an active area of research in this decade. It can be viewed as a special case of topical classification applied only to subjective portions of a document (sources of sentiment). Hence, the key task in document sentiment classification is extracting subjectivity. Existing approaches to extract subjectivity rely heavily on linguistic resources such as sentiment lexicons and complex supervised patterns based on part-of-speech (POS) information. This makes the task of subjective feature extraction complex and resource dependent. In this work, we try to minimize the dependency on linguistic resources in sentiment classification. We propose a simple and statistical methodology called review summary (RSUMM) and use it in combination with well-known feature selection methods to extract subjectivity. Our experimental results on a movie review dataset prove the effectiveness of the proposed methodology.  相似文献   
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Information use is defined as the application of acquired and transmitted information in the decision making of an organization at the strategic and tactical levels. The purpose of the research is to investigate how information use architecture impacts information load and usability at the operational level of manufacturing where machines, humans and the production processes are information users. A new approach to information load is introduced which takes all the characteristics of information use (tacit, mechanical, paper and digitized) and possibilities of users (machine, operator and process) into consideration. Information use nodes are conceptualized building blocks for information use architecture which impact information load and usability. The results suggest that information use load is sensitive to information encoding/decoding. A combination of the federated and integrated information use architectures tends to result in a low information use load and can become a strategic tool for waste reduction. How information usability relates to load varies depending on the usability characteristic in view. The major conclusion is that a holistic approach to information systems includes the consideration of information use architecture which is an important factor in the management of information load and usability at the operational level.  相似文献   
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Mentoring programmes have gained increasing popularity in institutions of higher education to support undergraduates in community service or outreach efforts. Many of these programmes partner mentors with inner‐city youth, providing assistance in underserved communities while mentors gain experiences that connect theory and practice. Here we report on two years of fieldwork in a Community Technology Centre that created mentoring partnerships in which 36 liberal arts undergraduates engaged with local youth to design, create, and build technology projects involving graphics, video, music, and animation. We analysed over 200 field notes, which described their mentoring interactions over eight weeks and conducted exit interviews about their mentoring experiences. Our results indicate that mentors participated not just as more knowledgeable peers but also as facilitators, advisors, observers and, most importantly, as learners in this process. In the interviews, nearly all mentors reviewed assumptions about their own learning and mentoring, in addition to reflections about social issues. We discuss the importance of these findings for conceptualising mentoring as a partnership by creating more equitable interactions in service learning initiatives. We also address the role of constructionist activities in facilitating learning opportunities for both mentors and mentees.  相似文献   
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ABSTRACT

This article reports on issues of diversity in the context of widening participation in global higher education (HE). Mature students represent a third of the HE student population in Australia, Canada, UK and the USA. More research is needed to understand factors that can facilitate or hinder access to HE for this group. The aim of this study was to examine factors that a small group of mature students perceived influenced them as they made the decision to take up HE. Six undergraduate students at a British university who were on track to finish their studies took part in semi-structured interviews. All participants were white and from families with no previous experience of HE. Mean age was 42.7 years (range 35–51), and 50% were female. The interviews were analysed using Interpretative Phenomenological Analysis. Through using phenomenological analysis to analyse perceptions of changing motivation and goals during the decision-making process to take up HE, a detailed understanding of the complexity of these change processes was obtained. The analysis offers evidence that mature students experience far-reaching personal and social changes related to their decision to enter HE and adds a novel understanding of these identity-changes. This new insight is of fundamental importance to the field because the novel understanding of mature students’ meaning-making could be used to tailor interventions to facilitate access to HE for mature students.  相似文献   
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Education and Information Technologies - This paper proposes an integrated research framework that takes advantage of the similarities of design science research (DSR) and Design-based research...  相似文献   
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