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The Alfred Taubman Medical Library at the University of Michigan has offered instruction in online literature searching to third-year pharmacy students as a component of the course "Drug Information and Scientific Literature Evaluation" since 1983. In the spring of 1989, a follow-up study was conducted to assess the impact of instruction on four classes of graduates. Of a pool of 151 graduates, 90 (60%) responded to a mailed questionnaire on their use of information and computerized literature searching. The respondents were divided into four subgroups: end-user searchers, users of intermediaries, end users who used intermediaries, and those who did not use computerized literature search systems. Seventy-two percent of the respondents used some type of computerized literature searching, and 42% performed their own searches. The four subgroups differed in general computer use, familiarity with MEDLINE search terminology, information use, reasons for using or not using literature searching, and characteristics of searches (i.e., type, time frame, amount, and frequency). Training in end-user search systems appears to have had an impact on the continued use of computerized literature searching several years after the formal educational program.  相似文献   
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Abstract

The 1980s was a period when the academic current for leisure studies led to the birth of the study of sports history. Japan was not a latecomer in this scholarly stream. More significantly, cultural issues were thought not the part of various phenomena in a society, but the key issues for class integration and class strife. After writing my PhD thesis on Pierce Egan, one of the earliest sport journalists influenced by the idea of early radicals in the nineteenth-century Britain, my attention turned over to the question of why the study of sport history was necessary. There was the academic impact inherited from the New Left’s belief that ‘without understanding the state of people’s culture, class issues are unable to be truly comprehended’. The Initiation of sport journalism had a similar destiny. This consequence appears to be a synchroflash between the early radicals’ concern in popular culture in the nineteenth century and the New Left’s interest in cultural studies in the twentieth century. There was an obvious reason why the radical essayists and contemporary academics had to pay attention to the ‘cultural turn’ with critical thinking in a society.  相似文献   
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We proposed and fabricated multiscale transparent arteriole and capillary vessel models with circular cross sections of 10-500 μm using photolithography. The circularities of the fabricated 10, 50, and 500 μm diameter microchannels were 84.0%, 61.5%, and 82.3%, respectively. Next, we connected these different models to realize a circulation type blood vessel model simulating arteriole networks. We proposed a novel connection method using an intermediate connector made of wax, which we used to connect these models to make a circulation model. In flow experiments, the fabricated models showed no leakage and circulation models with seamless connections were achieved.  相似文献   
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Abstract

The aim of this cross-sectional study was to compare body composition and risk factors of lifestyle-related diseases between young and older male rowers and sedentary controls. Healthy males aged 19–73 years participated in the study, and were divided into four groups: 26 young rowers, 24 senior rowers, 23 young sedentary controls, and 22 senior sedentary controls. Total and regional lean soft tissue, fat mass, and bone mineral density were measured using dual-energy X-ray absorptiometry. The HDL-cholesterol of senior rowers (67.4 ± 13.4 mg · dl?1) was significantly (P < 0.05) higher than that of senior sedentary controls (59.2 ± 11.9 mg · dl?1), while HDL-cholesterol was similar in senior rowers and young rowers (66.1 ± 10.8 mg · dl?1). Arm, leg, and trunk lean soft tissue mass were significantly higher in senior rowers (5.6 ± 0.6 kg, 18.2 ± 1.8 kg, and 27.3 ± 3.2 kg respectively) than in senior sedentary controls (5.1 ± 0.4 kg, 16.3 ± 1.4 kg, and 24.6 ± 1.7 kg respectively; P < 0.05). Bone mineral density was also significantly higher in senior rowers than in senior sedentary controls (ribs, lumbar spine, and pelvic segments; P < 0.05). We conclude that age-related increases in the risk of lifestyle-related diseases, such as osteoporosis and sarcopenia, are attenuated in male rowers. These results suggest that regular rowing exercise may have a positive influence in the prevention of lifestyle-related diseases in older Japanese people.  相似文献   
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The reciprocal effects among cognitive-behavioral, environmental, and biological influences on clinic-referred children's ( N = 64; 34 boys; M age 12.71 years) short-term psychological and psychiatric adjustment were studied. At clinic intake and 6 months later, standardized measures of adjustment and control-related beliefs were assessed. Before and after conflict-oriented parent-child interaction tasks the children's saliva was sampled. Adrenocortical responses (i.e., increases in salivary cortisol) to the social conflict task predicted children's internalizing problem behaviors and anxiety disorders at follow-up. Consistently high adrenocortical reactivity at intake and follow-up was associated with deflated social competence over the 6-month period. Also, specific patterns of discontinuity in children's internalizing behavior problems predicted individual differences in their subsequent adrenocortical responsiveness. Specifically, rising behavior problem levels across time predicted higher and declining behavior problem levels predicted lower adrenocortical reactivity at follow-up. Findings are among the first to suggest links among internalizing behavior problems, adrenocortical responsiveness to social challenge, and clinic-referred children's short-term cognitive-behavioral and emotional adjustment.  相似文献   
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ABSTRACT

Ankle flexibility is critical to obtain a high swimming velocity in undulatory underwater swimming (UUS). The present study investigated the Froude (propelling) efficiency and three-dimensional (3D) kinematics of human UUS following the extrinsic restriction of the ankle by tape application. In Experiment 1, swimmers (9 male and 8 female college swimmers) performed UUS trials involving normal swimming (Normal) and swimming with tape application at the ankle (Tape). Kicking frequency was controlled in both settings. UUS kinematics were obtained with a two-dimensional motion analysis. Swimming velocity significantly decreased during swimming with tape application compared with that during normal swimming (Normal, 1.33 m·s?1; Tape, 1.26 m·s?1, p < 0.05). The Froude efficiency was not affected (Normal, 0.77; Tape, 0.76), and ankle plantar angle did not decrease during swimming (Normal, 159.02°; Tape, 160.38°). In Experiment 2, lower limb rotations of a male swimmer were analysed using 3D motion analysis under the same conditions as Experiment 1. An insufficient forefoot rotation was observed during downstroke kicks (the phase of the highest acceleration to forward direction). These findings suggest that UUS velocity is affected by the mobility of end effector.  相似文献   
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