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This article reports on a study of which the main aim was to provide insight into whether increasing the enrolment of large classes influences student academic achievement at the University of KwaZulu-Natal (UKZN), City, South Africa. The massification of higher education has led to greater numbers of students being enrolled in contact programmes. there is a widely accepted inverse relationship between class size and academic achievement for small class sizes and it would be speculative to extend the same understanding to larger class sizes. It is within this context that a cross-sectional study was conducted during which student achievement was analysed against increasing the enrolment of already large classes, in selected undergraduate modules at UKZN over a period of four years. convenience sampling and judgemental sampling were used to select modules in the discipline of Supply Chain Management (SCM). The findings revealed that while the average class size increased significantly, the pass rates remained constant. Based on the study findings, it was concluded that an increase in the enrolment of already large classes does not influence student academic achievement. It is recommended that the study be replicated in other schools and faculties where disciplines have experienced similar increases in the enrolment of large classes, thereby presenting an opportunity to either validate or dispute the study results. It is further recommended that the role of peer effects be subjected to further study to establish whether they have any influence on academic achievement. These results are expected to encourage future debate on how faculties manage increasing student enrolments at higher education institutions.  相似文献   
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Psoriasis is chronic autoimmune hyperproliferative skin disease with a population prevalence of 1.5–3%. The cause of psoriasis is still not fully understood. It has been hypothesized to be an immune-mediated disorder in which the excessive reproduction of keratinocytes is due to cytokines such as interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha, secreted by infiltrating CD4+ and CD8+ T cells and natural killer cells. The aim of our study was to determine the serum levels of TNF-α, IL-4, IL-6 & IL-10 in psoriasis patients and compare it with healthy controls. 30 clinically diagnosed psoriasis patients and 30 age and sex matched healthy controls were included in the study. The serum cytokine levels were measured by solid phase sandwich ELISA (DIACLONE Research, France). TNF-α and IL-6 levels were significantly raised in patients and the results were statistically significant (P < 0.001). IL-4 levels were higher in patients than in controls (1.91 ± 4.7 pg/ml in cases & 0.9 ± 0.3 pg/ml in controls) but were not statistically significant. Interestingly, IL-10 levels were found to be higher in controls than in patients but again, it was not statistically significant. Pro-inflammatory cytokines play a pivotal role in the pathogenesis of psoriasis and it is the type 1(TH1) cytokine pattern, i.e., IL-6 & TNF-α, which predominate in the psoriatic T cell response. Further studies on IL-10 levels in psoriasis are recommended to establish their exact role in the pathogenesis of the disease.  相似文献   
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Student absenteeism at higher education institutions (HEIs) is a cause for concern as it has implications for students’ academic performance and therefore graduation rates. Graduation rates to some extent influence funding to which universities are entitled. This study aimed to establish the contextual factors that influenced student absenteeism at the Durban University of Technology (DUT), South Africa. A cross-sectional, quantitative study was conducted amongst 140 students in a single discipline in the management cluster. First-year students were found to have a greater tendency to be late for the first period (08:00) than second-year or third-year students. Furthermore, the students chose to absent themselves from class to study for tests; complete assignments; or engage in group work. The majority of the students absented themselves from classes on the day before a test as well as on the day of the test. The recommendations that emanated include the need to dedicate time for testing, during which no lectures are scheduled and to plan the timetable so that first-year lectures start in the second period (09:00).  相似文献   
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