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A pre-treatment methodology for clenbuterol hydrochloride (CLEN) isolation and enrichment in a complex matrix environment was developed through exploiting molecularly imprinted polymers (MIPs). CLEN-imprinted polymers were synthesized by the combined use of ally-β-cyclodextrin (ally-β-CD) and methacrylic acid (MAA), allyl-β-CD and acrylonitrile (AN), and allyl-β-CD and methyl methacrylate (MMA) as the binary functional monomers. MAA-linked allyl-β-CD MIPs (M-MAA) were characterized by Fourier transform-infrared (FT-IR) spectroscopy and a scanning electron microscope (SEM). Based upon the results, M-MAA polymers generally proved to be an excellent selective extraction compared to its references: AN-linked allyl-β-CD MIPs (M-AN) and MMA-linked allyl-β-CD MIPs (M-MMA). M-MAA polymers were eventually chosen to run through a molecularly imprinted solid-phase extraction (MISPE) micro-column to enrich CLEN residues spiked in pig livers. A high recovery was achieved, ranging from 91.03% to 96.76% with relative standard deviation (RSD) ≤4.45%.  相似文献   
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Outcome-focused career goals are concerned about studying for tangible career benefits. To what extent do these goals motivate distance learners to learn? Using a mixed-method design, Study 1 found that career-focused learners, when compared with noncareer-focused counterparts, had a propensity to endorse outcome-focused career goals, use surface strategies, value their learning, and achieve better course results. Interview findings showed that career-focused learners used a strategic approach to ensure the timely completion of tasks and examination preparation. Study 2 located two groups of career-focused learners (autonomous and controlled) who endorsed outcome-focused career goals, alongside a noncareer-focused group. MANOVA analyses found that autonomous and noncareer-focused learners had engaged learning patterns. Although controlled learners were less engaged in learning, they achieved better results. It was concluded that outcome-focused career goals are significant sources of motivation for distance learners, despite being extrinsic to learning.  相似文献   
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Research Findings: This study examined how child negative emotionality interacted with mothers’ self-reported parenting in predicting different aspects of social functioning among very young Chinese children. A total of 109 Chinese nursery children in Hong Kong participated with their parents. Maternal supportive and aversive parenting practices were reported by mothers, and child negative emotionality and social functioning were reported by both mothers and fathers. The results revealed interaction effects between child negative emotionality and mothers’ self-reported parenting on children’s internalizing problems, externalizing problems, and social-emotional skill deficiency. Specifically, children with high negative emotionality were more susceptible to the negative effects of aversive parenting (i.e., showing more internalizing and externalizing problems when exposed to aversive parenting) than their peers with low negative emotionality. Negative emotionality also placed young children at risk for social-emotional skill deficiency, especially when they received less support from their mothers compared to their peers. Practice or Policy: Special attention should be paid to the social functioning of Chinese children with higher levels of negative emotionality, because these children are more vulnerable to poor-quality parenting at a very young age.  相似文献   
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Promoting in-service teachers’ continuous professional learning is indispensable to educational reforms that demand knowledge acquisition and practice innovation. Addressing this issue, this mixed-method study examined the relationship between teachers’ professional selves and continuous professional learning. Two hundred and nighty-one practicing teachers completed a questionnaire that assessed their current and future professional selves, learning motives, strategy use, self-efficacy, control beliefs, learning interests and intentions. Cluster analyses found that strongly-committed teachers who held strong professional selves had the most engaged patterns of learning followed by teachers who had moderate and weak levels of professional selves. Study two was a follow-up interview study with eight selected teachers who held contrasting professional selves. Strongly-committed teachers discussed their hoped-for selves while weakly-committed teachers expressed concerns about heavy workload and the selves that they feared. These two groups of interviewees differed in the strategies they employed to complete course assignments.  相似文献   
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Schools in Singapore are now tasked to develop the spirit of innovation and enterprise in their students. This is in line with the national vision of ‘Thinking Schools, Learning Nation’. This policy initiative, which began in 2004, is set to change the fundamental nature of education in Singapore. This article discusses the innovation and enterprise (I&E) initiative, its major implications for schools in Singapore and the areas still to be addressed in the implementation of the policy. In particular, the article discusses the issues of teachers and school leaders as role models of I&E, I&E as an organic part of school business, the influence of the wider societal culture and values system, and the measurement of success of I&E. The challenge for schools is to go beyond the form of the initiative to bring real substantial and sustainable change through this movement.  相似文献   
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Although the importance of language in science learning has been widely recognized by researchers, there is limited research on how science teachers perceive the roles that language plays in science classrooms. As part of an intervention design project that aimed to enhance teachers’ capacity to address the language demands of science, interview data (N = 9) were collected to understand teachers’ perceptions and experiences with a wide range of issues related to language use in science classrooms. Adopting an interpretive approach to qualitative data, the analysis revealed that the teachers perceive a wide range of student difficulties related to language use in science classrooms, especially to the use of specialized terms and writing. Although the teachers are keenly aware of how language can be a barrier to learning science, they are less certain as to what students need to know about the language of science in order to master it. The findings suggested professional support that highlights the distinctive language demands of science and how these demands differ from other subject areas could be useful to these elementary school teachers.  相似文献   
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面授和网上教学有机结合的整合式教学越来越成为高校教育和培训的主要模式。本文旨在介绍和分析香港理工大学教学发展中心(简称EDC)如何通过网上教学平台的功能,与面授教学结合起来,发挥面授教学和网上教学的各自优势,使教师培训更加有效。EDC的实践表明,在大学教师培训课程中,发挥网上教学的优势,能帮助学员弥补由于有限的面授教学产生的师生之间、学员和学员之间互动的不足。在网上学习中,通过互相的学习观摩和观念碰撞,能激发学员的学习兴趣,有效地促进学员之间进行探究性学习,同时,这种集体学习的方法,能促进在职教师之间的友好交往和学术交流。  相似文献   
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Relatively little work has focused on inclusive education in Singapore. This study examines the experiences and perceptions of parents whose children with disabilities are attending mainstream secondary schools in Singapore. Data was drawn from interviews with 13 parents of children with mild disabilities. Our findings reveal that parental perspective on inclusive education in Singapore is not only about classroom support but also reflects a deeper concern about whether their children with disabilities will emerge from school as contributing individuals in society. While parents strive to effectively include their children with disabilities in mainstream classrooms, there were dichotomies in their (1) understanding of disabilities, (2) expectations of school support, and (3) expectations for their child with disabilities. Given that academic and social prowess is a critical prerequisite to have a shot at entering the meritocratic Singapore society, the tension parents experience is to gauge a reasonable amount of pressure to exert on their children, the school and themselves as they assert their children's educational entitlements within an imperfect but evolving state of inclusion.  相似文献   
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