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Measuring academic growth, or change in aptitude, relies on longitudinal data collected across multiple measurements. The National Educational Longitudinal Study (NELS:88) is among the earliest, large-scale, educational surveys tracking students’ performance on cognitive batteries over 3 years. Notable features of the NELS:88 data set, and of almost all repeated measures educational assessments, are (a) the outcome variables are binary or at least categorical in nature; and (b) a set of different items is given at each measurement occasion with a few anchor items to fix the measurement scale. This study focuses on the challenges related to specifying and fitting a second-order longitudinal model for binary outcomes, within both the item response theory and structural equation modeling frameworks. The distinctions between and commonalities shared between these two frameworks are discussed. A real data analysis using the NELS:88 data set is presented for illustration purposes. 相似文献
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Nidhi Gupta Ramesh Kandimalla Kumari Priyanka Gagandip Singh Kiran Dip Gill Surjit Singh 《Indian journal of clinical biochemistry : IJCB》2014,29(1):69-73
Dietary and lifestyle factors have been shown to have a profound effect on paraoxonase-1 (PON1) activity. Cigarette smoke has been shown to inhibit its mass and activity where as resveratrol has been shown to enhance it. We exposed hepatoma derived cell line (HepG2) to resveratrol and nicotine in varying doses and measured PON1 enzymatic activity and PON1 gene expression. In addition, total protein content of HepG2 cells was also measured. Resveratrol in a dose of 15 μmol/l or above significantly increased the PON1 enzyme activity (p > 0.001) where as nicotine in a dose of 1 μmol/l or higher significantly reduced it (p < 0.05). The resveratrol in this dose also enhanced the PON1 gene expression whereas nicotine decreased it as compared to controls. However, the protein conent of cells was not changed suggesting that they were not cytotoxic in the doses used. Till date the antioxidant vitamins have shown disappointing results against LDL oxidation and cardiovascular protection. However, the effect of resveratrol on PON1 gene expression and activity was significant, suggesting increase in PON1 activity and enhanced gene expression may be its alternative mechanism for offering protection against cardiovascular disease and may be an potential pharmacological agent which can be used for this. 相似文献
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Nidhi Singal 《International Journal of Inclusive Education》2019,23(7-8):827-840
ABSTRACTAcross the globe, the Salamanca Statement has provided the strongest impetus for drawing attention to the education of some of the most marginalised groups. In India, it has had a significant and specific impact on the provision of schooling opportunities for children with disabilities. This paper provides a critical analysis of key developments in national policies and programmes and how these have shaped provision at the classroom level. Drawing on Nancy Fraser’s conception of justice as an analytical tool, efforts towards inclusive education in India are explored through the interlinked ideas of redistribution, recognition and representation. Over the last two decades, there has been a significant increase in the numbers of children with disabilities being enrolled in schools, driven by factors including, positive legislation and the increased provision of aids and appliances, etc. However, little attention has been paid to the quality of teaching and learning, experienced by children with disabilities. Instead, efforts remain focused on assimilation into a mainstream system fraught with different challenges. Despite these issues, India is a powerful example of how the vision of inclusive education, as outlined in the Salamanca Statement, is feasible, especially if efforts build on contextual realities. 相似文献
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This article explores developments towards inclusive education being undertaken in some schools in India. Drawing on data collected through interviews with key professionals working in schools and classroom observations, the study focused on the practices and experiences of professionals involved in these efforts. Findings suggest that these schools had provided access to children who would otherwise have been denied admission to the mainstream due to their disabilities. However, these children remained the ‘included’ children and did not necessarily become a part of the classroom. Thus, evident in these schools were a range of exclusionary practices that continued to exist alongside efforts towards inclusion. I therefore argue that there is not only a need to provide stakeholders with the knowledge and skills for developing inclusive teaching practices, but also a need to challenge existing values, beliefs and attitudes to ensure the full participation of all children in the curriculum and culture of their school setting. 相似文献
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Nidhi Singal 《International Journal of Disability, Development & Education》2006,53(3):351-369
This article examines education of children belonging to marginalised groups, with particular reference to children with disabilities, within the Indian context. Based on an analysis of post‐independence Government documents, various educational provisions made available for children with disabilities are discussed. It explores the Indian Government’s focus on the development of special schools, its efforts towards integration, and the more recent emphasis on inclusive education. Furthermore, it attempts to elucidate “inclusive education” as understood in various official documents. The article concludes by arguing for a need to develop a contextual understanding of inclusive education that is reflective of current educational concerns in India. 相似文献
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A Second-Order Conditionally Linear Mixed Effects Model With Observed and Latent Variable Covariates
A conditionally linear mixed effects model is an appropriate framework for investigating nonlinear change in a continuous latent variable that is repeatedly measured over time. The efficacy of the model is that it allows parameters that enter the specified nonlinear time-response function to be stochastic, whereas those parameters that enter in a nonlinear manner are common to all subjects. In this article we describe how a variant of the Michaelis-Menten (M-M) function can be fit within this modeling framework using Mplus 6.0. We demonstrate how observed and latent covariates can be incorporated to help explain individual differences in growth characteristics. Features of the model including an explication of key analytic decision points are illustrated using longitudinal reading data. To aid in making this class of models accessible, annotated Mplus code is provided. 相似文献
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V. Nagarjuna Maturu Nidhi Gupta Gagandip Singh Kirandip Gill Yash Paul Sharma Surjit Singh 《Indian journal of clinical biochemistry : IJCB》2013,28(3):248-254
Human serum paraoxonase-1 (PON1), an enzyme on HDL prevents oxidation of LDL thereby preventing the development of atherosclerosis. Studies done so far have lead to conflicting results. As studies are lacking in North-West Indian Punjabi’s, a distinct ethnic group with high incidence of coronary artery disease, we determined PONase activity in this population. It has been postulated that sudden lowering of serum PONase may lead to precipitation of acute myocardial infarction. We determined serum PONase activity and lipids in 100 patients each of AMI (within 24 h of onset), stable CAD and 100 age and sex matched healthy controls. These were again determined after 6 weeks in AMI patients. The mean serum PONase activity was lowest in AMI patients (23.26 U/ml) followed by stable CAD patients (102.0 U/ml) where as in controls was highest (179.8 U/ml). In patients with AMI, activity was significantly higher at 6 weeks as compared to that after acute event (49.39 %; p < 0.05). Sudden lowering of serum PONase activity in a population which already has lower activity may be one of the risk factors for development of AMI. 相似文献
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John F. Pane Daniel F. McCaffrey Nidhi Kalra Annie J. Zhou 《Journal of Education for Students Placed at Risk》2013,18(2-3):168-211
The combined impact of Hurricanes Katrina and Rita in 2005 left the education system in the Gulf Coast region of the United States with tremendous challenges to rebuild infrastructure, reestablish services, and accommodate the movements of students that occurred as result of the storms. This article focuses on Louisiana's public school students, of whom 1/4 were displaced as a result of the storms. It explores the experiences of students and the effects of student movements on student achievement and on the state's public education system during the first academic year following the hurricanes. Results suggest that, overall, the education system handled the disruptions of the disaster relatively well. However, more detailed examinations show that some displaced students had problems such as nonenrollment or poor attendance, mental health or behavioral problems, and academic setbacks. Negative achievement effects, which were small overall, were most pronounced among students who remained displaced for the duration of the academic year, and appeared to be mitigated by students' tendency to enroll in schools with higher student performance than their original schools. Additional results show that the negative effects were associated with both the number of schools attended and the amount of school time lost. However, these analyses do not include the displaced students who did not reenroll in a Louisiana public school. These students constitute more than a 1/4 of displaced students and tended to be those who are most at risk for poor academic outcomes. 相似文献