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We recruited 59 individuals of known HIV serostatus after informed consent however, 44 were serodiscordant heterosexual partners
[serodiscordant seronegative (SSN group) and serodiscordant seropositive (SSP group)] while 15 were seronegative healthy individuals
(SNH). In the case–control study we choose to determine Malondialdehyde (MDA) concentration as a marker of lipid peroxidation
index (oxidative stress) spectrophotometrically and quantify HIV mRNA by Real Time-nucleic acid sequence based amplification
assay (RT-NASBA). Here our result show for the first time a high concentration of lipid peroxidation product (MDA, 116.6%)
with a significant (P < 0.05) increase in HIV serodiscordant seropositive subjects over their seronegative partners. However, Spearman rank correlation
statistics of SSP group showed a positive correlation value (P < 0.01, r = 0.89) between MDA and mRNA and a negative correlation between MDA and T-cell ratio (P < 0.01, r = 0.96).The study may strongly indicate a possible lipid peroxidation product threshold for predicting HIV infection and
progression in serodiscordant heterosexual partners. 相似文献
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Okeke Chinedu Ifedi Onochie 《美中教育评论》2010,7(6):16-30,44
The females＇ relatively low participation in higher education is discussed within the Nigerian society in a way that such issues are discursively placed in often contradictory, as well as extremely complicated contexts. Dominant discussions draw on the interplay between gender and students＇ performance across subjects, as well as on the influences of the often patriarchal school environment on students＇ overall performance, which with little or no attention given to parental and domestic agencies. This paper is an account of the stories of the experiences of schooling about some Nigerian school girls from the perspective of their families. The larger study from which this paper derives, examined the gendered perception of schooling amongst some senior secondary school students in a Nigerian suburb. A number of discussions among the 25 girls （and 25 boys） who participated in the study were analyzed to understand how gender played in their perceptions of schooling influences upon their lives. As this project was grounded in the interpretivist qualitative research paradigm, discursive interpretivist approach was employed to interrogate how parental and domestic agencies, can play upon the aspirations of young girls for higher education in both complex and subtle ways. Recommendations for changes in policy and practice are made. 相似文献
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