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1.
Munjed Al Muderis Horst Heinrich Aschoff Belinda Bosley Guy Raz Ludger Gerdesmeyer Brendan Burkett 《Sports Engineering》2016,19(3):141-145
Lower limb amputees often experience complications with the use of conventional socket-type prostheses, which further reduce their already compromised ability to perform the activities of daily living, or to participate in sporting activities. During the last two decades, a new technology of direct skeletal attachment (osseointegration) of prosthesis to the femoral residuum has been developed. The aim of this research was to assess the implant design, surgery protocols, and functional testing of this new technology on the first 100 patients using the Integral Leg Prosthesis procedure. This new knowledge can guide future engineering developments of osseointegration within the sporting arena. Between 1999 and 2013, direct skeletal implantation was performed on 112 amputees, from two centres in Germany and Australia. From the experience of the surgical team, modifications were made to the implant design. This re-engineering of the implant has reduced the surgical revisions due to infection from 29 % with the early implant design down to 7 %. The functional testing of the 34 Australian cases were assessed pre- and 12 months post-implant with significant improvements of one complete K-scale; the Q-TFA measures increased (50.9–86.7), whilst the Timed Up and Go decreased significantly (12.43 s ± 3.89 to 8.03 s ± 2.80), and the 6 min walk increased (304.0–383.9 m). From these findings, osseointegration technology is realistically the way of the future for amputee athletes. Further refinement of the implant design and sports-specific functional testing are required to define the potential of this technology. 相似文献
2.
Nonverbal communication skills in Down syndrome children 总被引：4，自引：0，他引：4
The goal of this research was to examine the nonverbal communication competence of 18-48-month-old Down syndrome children. The results indicated that Downs children displayed strengths and weaknesses in nonverbal communication skills. Relative to MA matched normal children, they displayed a significant strength in nonverbal social interaction skills. However, they also displayed a significant deficit in nonverbal requests for objects or assistance with objects compared to normals. This pattern of strength and weakness in nonverbal skills appeared to be specific to Down syndrome since this pattern was not displayed by a comparison sample of non-Downs mentally retarded children. Nonverbal object-requesting skill was also significantly associated with a measure of expressive language in the Downs sample. This relation was notable because the Downs children also displayed a deficit in expressive language. Thus, the results of this study suggest that a deficit in expressive language is associated with a deficit in earlier-developing nonverbal requesting skill among Down syndrome children. 相似文献
3.
Thirsty Sprague-Dawley rats drank flavored water in a wind tunnel prior to lithium-induced toxicosis. Flavors were presented for 5 min; 30 min later a toxin, lithium chloride, was injected. After the rats had recovered, subsequent aversions to the taste and the odor were assessed separately. In Experiment 1, extensive preexposure to the taste component of the flavor attenuated neophobia to the flavor and the subsequent taste aversion. However, the subsequent odor aversion was unaffected. Experiment 2 partially replicated the results of Experiment 1 and showed that, in a situation in which only taste-potentiated odor aversions are usually found, nonpotentiated aversions were evident. Experiment 3 found that, in addition to attenuating taste aversions, taste preexposure enhances the capacity of rats to learn nonpotentiated odor aversions. The results are interpreted with a neural-based model of conditioned flavor aversions. 相似文献
4.
CE:Teens曾在2009年7月号的娱乐直播室提及3D风逐渐兴起的电影趋势。经过近两年的发展,而今电影院里似乎随便一部电影都可以带上特制眼镜享受身临其境的快感——听力小提示:这篇访谈语速稍快,但风格幽默搞笑,可以作为泛听材料进行练习。先脱离文字听一遍声音,看看你能否归纳出这段对话中提出了几个方面的问题,被访者对此又是如何作答的呢? 相似文献
5.
Melanie Killen Amanda R. Burkholder Alexander P. D'Esterre Riley N. Sims Jacquelyn Glidden Kathryn M. Yee Katherine V. Luken Raz Laura Elenbaas Michael T. Rizzo Bonnie Woodward Arvid Samuelson Tracy M. Sweet Laura M. Stapleton 《Child development》2022,93(3):732-750
The Developing Inclusive Youth program is a classroom-based, individually administered video tool that depicts peer-based social and racial exclusion, combined with teacher-led discussions. A multisite randomized control trial was implemented with 983 participants (502 females; 58.5% White, 41.5% Ethnic/racial minority; Mage = 9.64 years) in 48 third-, fourth-, and fifth-grade classrooms across six schools. Children in the program were more likely to view interracial and same-race peer exclusion as wrong, associate positive traits with peers of different racial, ethnic, and gender backgrounds, and report play with peers from diverse backgrounds than were children in the control group. Many approaches are necessary to achieve antiracism in schools. This intervention is one component of this goal for developmental science. 相似文献
6.
Seriation, conservation, and theory of mind abilities were examined in individuals with autism ( N = 16), mental retardation ( N = 16), and in normally developing children ( N = 16). Seriation tasks included seriation of tubes, blocks, and flat squares. Conservation tasks included conservation of area, number, substance, quantity, and weight. Theory of mind tasks involved predicting false belief and understanding value and fact beliefs. Participants with autism performed better than participants with mental retardation on seriation, while no differences emerged between these groups on conservation and false belief. Individuals with autism performed less well than individuals with mental retardation on the value and fact belief tasks; however, when verbal ability was held as a covariant, the difference was no longer significant. Normally developing children performed better than the other two groups on all tasks. These results suggest that autism does not involve a specific impairment in theory of mind and that theory of mind deficits are not unique to autism. 相似文献
7.
In the current study (a) maternal insightfulness into the experience of the child and (b) resolution with respect to the child's diagnosis and their associations with children's security of attachment were examined in a sample of 45 preschoolers (mean age = 49 months) with autism spectrum disorders (ASD). It was hypothesized that mothers who were insightful and resolved would be more likely to have securely attached children than mothers who were neither insightful nor resolved. The findings supported this hypothesis. The implications of insightfulness and resolution for child attachment in the context of ASD are discussed. 相似文献
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9.
A content analysis of 584 prime-time programs examines messages about sex on Israeli television, comparing local and foreign shows. A 2-week composite sample from 7 commercial broadcast, cable, and satellite channels is analyzed. Results show that sexual content is highly prevalent, with a significantly higher frequency in foreign than local shows. Less than 20% of programs with sexual content address sexual health and risks; foreign shows again exceed local ones. Few differences emerge between local and foreign content in the contextual presentation of sex. Findings are discussed in light of theory, research, and implications for audience effects, policy, and education. 相似文献
10.
Uwe Tangen Gabriel Antonio S. Minero Abhishek Sharma Patrick F. Wagler Rafael Cohen Ofir Raz Tzipy Marx Tuval Ben-Yehezkel John S. McCaskill 《Biomicrofluidics》2015,9(4)
Nanoscale synthetic biology can benefit from programmable nanoliter-scale processing of DNA in microfluidic chips if they are interfaced effectively to biochemical arrays such as microwell plates. Whereas active microvalve chips require complex fabrication and operation, we show here how a passive and readily fabricated microchip can be employed for customizable nanoliter scale pipetting and reaction control involving DNA. This recently developed passive microfluidic device, supporting nanoliter scale combinatorial droplet generation and mixing, is here used to generate a DNA test library with one member per droplet exported to addressed locations on microwell plates. Standard DNA assembly techniques, such as Gibson assembly, compatible with isothermal on-chip operation, are employed and checked using off-chip PCR and assembly PCR. The control of output droplet sequences and mixing performance was verified using dyes and fluorescently labeled DNA solutions, both on-chip and in external capillary channels. Gel electrophoresis of products and DNA sequencing were employed to further verify controlled combination and functional enzymatic assembly. The scalability of the results to larger DNA libraries is also addressed by combinatorial input expansion using sequential injection plugs from a multiwell plate. Hence, the paper establishes a proof of principle of the production of functional combinatorial mixtures at the nanoliter scale for one sequence per well DNA libraries. 相似文献