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1.
Although angiogenetic therapy using recombinant growth factors holds much hope for the treatment of ischaemic diseases, there are still many unanswered questions, including the method of administration, the correct dose of these factors, and the duration of the therapeutic approach. Exercise has also been suggested to induce neovascularizaiton in muscles. We evaluated the angiogenetic effects of the intramuscular administration of basic-fibroblast growth factor (b-FGF) and acidic-fibroblast growth factor (a-FGF) in rat heart, compared with rats who exercised daily. In conclusion, both the intramuscular administration of b-FGF and exercise increased significantly angiogenesis in the heart in contrast to the intramuscular administration of a-FGF, which was ineffective.  相似文献   
2.
A structured questionnaire was administered to assess Greek pre-service primary teachers' knowledge, attitudes, and self-reported behavior toward marine pollution issues. Exploratory factor analysis revealed several factors, all demonstrating adequate internal consistency, and showed that pre-service teachers demonstrated a moderate level of knowledge about marine pollution issues, although they also held misconceptions. They scored high or relatively high on all attitude factors, and scored moderately high on individual action and low on collective action. These findings can contribute to the design and implementation of teacher education programs focused on the marine environment and its conservation.  相似文献   
3.
Despite the importance of body donation for medical education and the advancement of medical science, cadaveric donation remains suboptimal worldwide. The purpose of this study was to evaluate the willingness of body donation in Greece and determine the characteristics of donors. This cross‐sectional questionnaire survey was conducted from January to June 2011. A specially designed questionnaire was distributed to 1,700 individuals who were randomly selected from five major Greek cities. It was found that higher educational levels (P = 0.002), annual family income below 30,000 Euros (P = 0.001), guaranteed employment status (P = 0.02), and the presence of comorbid conditions (P = 0.004) seemed to affect potential donors' willingness for cadaveric donation. Those with strong religious beliefs were found to be unwilling to donate their bodies to medical science. Interestingly, the majority of participants who believed that hospitalized patients are deceived or are used for harmful experiments were willing to become whole body donors (P = 0.043). In Greece, the rate of body donation to medical science remains low, and most Greek citizens are not willing to become body donors. Efforts to encourage discussions about whole body donation should be implemented in order to improve current low levels of donation. Anat Sci Educ. © 2012 American Association of Anatomists.  相似文献   
4.
Abstract

Although angiogenetic therapy using recombinant growth factors holds much hope for the treatment of ischaemic diseases, there are still many unanswered questions, including the method of administration, the correct dose of these factors, and the duration of the therapeutic approach. Exercise has also been suggested to induce neovascularizaiton in muscles. We evaluated the angiogenetic effects of the intramuscular administration of basic-fibroblast growth factor (b-FGF) and acidic-fibroblast growth factor (a-FGF) in rat heart, compared with rats who exercised daily. In conclusion, both the intramuscular administration of b-FGF and exercise increased significantly angiogenesis in the heart in contrast to the intramuscular administration of a-FGF, which was ineffective.  相似文献   
5.
The purpose of this study was dual: First, to develop and validate assessment schemes for assessing 11th grade students’ meaningful understanding of organic chemistry concepts, as well as their systems thinking skills in the domain. Second, to explore the relationship between the two constructs of interest based on students’ performance on the applied assessment framework. For this purpose, (a) various types of objective assessment questions were developed and evaluated for assessing meaningful understanding, (b) a specific type of systemic assessment questions (SAQs) was developed and evaluated for assessing systems thinking skills, and (c) the association between students’ responses on the applied assessment schemes was explored. The results indicated that properly designed objective questions can effectively capture aspects of students’ meaningful understanding. It was also found that the SAQs can elicit systems thinking skills in the context of a formalistic systems thinking theoretical approach. Moreover, a significant relationship was observed between students’ responses on the two assessment strategies. This research provides evidence that students’ systems thinking level within a science domain is significantly related to their meaningful understanding of relative science concepts.  相似文献   
6.
Melt and fluid inclusions were studied in the minerals of Cenozoic olivine melanephelinites from the Chukehi Peninsula, Russia. The rock contain several generations of olivine phenocrysts varying in composition at mg=0.88 - 0.77. The phenocrysts bear fluid and melt inclusions recording various stages of melt crystallization in volcanic conduits and shallow magma chambers. Primary fluid inclusions are CO2-dominated with a density of up to 0.93 g/cm^3. All fluid inclusions are partially leaked, which is indicated by haloes of tiny fluid bubbles around large fluid inclusions in minerals. Melt inclusions contain various daughter crystals, which were completely resorbed in thermometric experiments at about 1230~C. Assuming that this temperature corresponds to the entrapment conditions of the CO2 fluid inclusions, the minimum pressure of the beginning of magma degassing is estimated as 800MPa. Variations in the compositions of homogenized silicate melt inclusions indicate that olivine was the earliest crystalline phase followed by clinopyroxene, nepheline and orthoclase. This sequence is in agreement with the mineralogy of the rocks. The melts are strongly enriched in incompatible trace elements and volatiles （in addition to CO2 , high C1, F, and S contents were detected）. There are some differences between the compositions of melts trapped in minerals from different samples. Variations in SiO2 , FeO, and incompatible element contents are probably related to melt generations at various levels in a homogeneous mantle reservoir.  相似文献   
7.
The purpose of this study was to assess the effectiveness of a short intervention program designed to enhance the educators' ability to identify children with developmental coordination disorder (DCD). Twenty early childhood and 20 physical education teachers (n = 40) participated in the study. Participants were randomly assigned into an experimental group (n = 20) and a control group (n = 20). A 3-week intervention program implemented, which comprised of four 2-hour lectures and two practice sections of the same duration and focused on the issue of DCD within the educational setting. After the completion of the program, each educator evaluated four children's motor performance using the Movement Assessment Battery for Children Checklist (Sugden & Sugden, 1991 Sugden, D. A. and Sugden, L. 1991. The assessment of movement skill problems in 7- and 9-year-old children. British Journal of Educational Psychology, 61: 329–345. [Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). Subsequently, another assessment took place using the Movement Assessment Battery for Children. The total number of evaluated children was 160. Results showed that the educators who attended the educational program showed higher identification ability. No significant differences were found between physical education and early childhood teachers of the experimental group. On the contrary, in the control group, early childhood teachers exhibited higher identification ability than the physical education teachers. The intervention program significantly enhanced the educators' ability to identify children with DCD. The implication of this study is that the education of school professionals should be a continuous process.  相似文献   
8.
The present study is concerned with an exploration of counselling needs of students at two Greek universities as well as their attitudes to utilizing a university counselling centre. The sample consisted of 312 students who completed a Greek version of the Rutgers Needs Assessment Questionnaire as well as a subscale on Attitudes towards the Counselling Centre. The analysis of the data indicated that issues about relationships, goal setting and problem-solving were the main concerns of the participants. It was also found that students, especially those who faced some kind of psychological difficulties, held a negative attitude towards visiting a university counselling centre.  相似文献   
9.
Demographic and performance data from 197,825 athletes competing in “Engadin Ski Marathon” between 1998 and 2016 were analysed. When all finishers per age group were considered, there was no gender difference in time (2:59:00 in women versus 2:59:09 h:min:s in men; P = 0.914, η2 < 0.001) and the main effect of age group on time was trivial (P < 0.001, η2 = 0.007). When the top 10 finishers per age group were considered, men were faster than women (1:27:32 versus 1:34:19 h:min:s, respectively; P < 0.001, η2 = 0.373), there was a large effect of age group on time (P < 0.001, η2 = 0.590) and the gender difference was larger in the older than in the younger age groups (P < 0.001, η2 = 0.534). The age of peak performance for all finishers by 1-year interval age group was 40.3 and 39.6 years in all women and men, respectively. The top 10 finishers by 1-year interval age group achieved their peak performance in the age of 38.4 and 42.2 years in women and men, respectively. The age of peak performance was older and the age-related performance decline occurred earlier in marathon cross-country skiing, compared to road-based marathon running.  相似文献   
10.
The aim of the present study was to respond to the increasing demand for comprehensive tools for the measurement of ocean literacy, by investigating the psychometric characteristics of a Greek version of the Survey of Ocean Literacy and Experience (SOLE), an instrument that assesses conceptual understanding of general ocean sciences content, focusing on the knowledge component. Four hundred twenty-one pre-service primary school teachers participated in a cross-sectional study. The dichotomous Rasch model was used to examine the measurement properties of the SOLE, namely, person-item targeting and separation, reliability, dimensionality and differential item functioning (DIF). Steps were taken to improve the instrument, where any of these attributes were outside acceptable ranges. Results suggested that a modified SOLE showed an adequate fit to the Rasch model, is unidimensional, free of DIF, and is particularly well-suited to the population under study. Our findings suggest that the SOLE constitutes a valuable tool which can be applied to a different cultural context and population. The proposed use of the instrument could contribute to the assessment of the quality of marine education in school-based and non-formal education contexts and to the cross-cultural comparison of ocean literacy, which are prerequisites for the improvement of ocean literacy.  相似文献   
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